Recently added

Research Articles (Internal Medicine): Recent submissions

  • The mechanism of action of oral antidiabetic drugs : a review of recent literature 
    Bosenberg, Liesel H.; Van Zyl, Danie G. (Health & Medical Publishing Group, 2008-12)
    Type 2 diabetes mellitus (DM) is a disorder that is placing an increasing burden on health service delivery worldwide. Consequently, it has become increasingly important that physicians who treat such patients have a good ...
  • Autonomic response to exercise as measured by cardiovascular variability 
    Grant, C.C. (Catharina Cornelia); Ker, James A. (Health and Medical Publishing Group, 2008)
    MOTIVATION: There is growing interest in the use of cardiovascular variability indicators as measures of autonomic activity,even though reported results are not always comparable or as expected. This review aims to determine ...
  • Salmonella typhimurium meningitis in an adult patient with AIDS 
    Swe Swe-Han, K .; Nagel, G.; Van der Westhuizen, M.; Hoosen, Anwar Ahmed (BMJ, 2008-01)
    Salmonella meningitis is an unusual complication of Salmonella sepsis and occurs mainly in children. A rare case of Salmonella typhimurium meningitis occurring in an adult HIV positive man who presented with a history of ...
  • Survey on knowledge and attitudes regarding diabetic inpatient management by medical and nursing staff at Kalafong Hospital 
    Van Zyl, Danie G.; Rheeder, Paul (Health and Medical Publishing Group, 2008-12)
    ObBJECTIVE: The objective of this study was to evaluate perceptions regarding current practices in the care of diabetic inpatients as well as the knowledge and attitudes of nursing and medical caregivers at a large secondary ...
  • Knowledge of foot care in people with diabetes in a tertiary care setting 
    Rheeder, Paul; Venn, Marie; De Korte, Ewald; Van Zyl, Danie G. (Health and Medical Publishing Group, 2008-12)
    BACKGROUND: The objective of this study was to investigate levels of foot care knowledge among patients attending the diabetes clinic at Pretoria Academic Hospital by comparing the knowledge of patients with ‘at risk’ feet ...
  • Diffuse infiltrative lymphocytosis syndrome (DILS) 
    Levay, Peter Ferenc; Botes, M.E. (Medpharm Publications, 2008-03)
    Diffuse infiltrative lymphocytosis syndrome (DILS) is characterised by a persistent CD8+ lymphocytosis and lymphocytic infiltration of various organs. The reported prevalence varies between 0.85 – 3%, and appears to be ...
  • Risk factors precipitating exacerbations in adult asthma patients presenting at Kalafong Hospital, Pretoria 
    Geyser, M.M. (Mimi); Rheeder, Paul (Medpharm Publications, 2008-07)
    BACKGROUND: Research into asthma is proceeding at an unprecedented rate and yet we live with a disease that escalates in prevalence and severity, despite a greater understanding of its pathophysiology and the necessary ...
  • Decision-making using absolute cardiovascular risk reduction and incremental cost-effectiveness ratios : a case study 
    Ker, James A.; Oosthuizen, H.; Rheeder, Paul (Clinics Cardiv, 2008-03)
    BACKGROUND: Many clinical guidelines have adopted a multifactorial cardiovascular risk assessment to identify high-risk individuals for treatment. The framingham risk chart is a widely used risk engine to calculate the ...
  • Glycaemic control improves fibrin network characteristics in type 2 diabetes : a purified fibrinogen model 
    Pieters, Marlien; Covic, Namukolo; Van der Westhuizen, Francois Hendrikus; Nagaswami, Chandrasekaran; Baras, Yelena; Loots, Du Toit; Jerling, Johann C.; Elgar, Dale; Edmondson, Kathryn S.; Van Zyl, Danie G.; Rheeder, Paul; Weisel, John W. (Schattauer, 2008-04)
    Diabetic subjects have been shown to have altered fibrin network structures.One proposed mechanism for this is non-enzymatic glycation of fibrinogen due to high blood glucose.We investigated whether glycaemic control would ...
  • An African origin for the intimate association between humans and Helicobacter pylori 
    Linz, Bodo; Balloux, Francois; Moodley, Yoshan; Manica, Andrea; Liu, Hua; Roumagnac, Philippe; Falush, Daniel; Stamer, Christiana; Prugnolle, Franck; Van der Merwe, Schalk Willem; Yamaoka, Yoshio; Graham, David Y.; Perez-Trallero, Emilio; Wadstrom, Torkel; Suerbaum, Sebastian; Achtman, Mark (Nature Publishing Group, 2007-02)
    Infection of the stomach by Helicobacter pylori is ubiquitous among humans. However, although H. pylori strains from different geographic areas are associated with clear phylogeographic differentiation the age of an ...
  • The prevention of ventilator associated pneumonia in clinical practice - What can be done to lower the risk? 
    Mostert, Chris J. (Medpharm Publications, 2008-03)
    Nosocomial infections are an important and frequent cause of morbidity and mortality in hospitals. Besides these factors, there are tremendous cost implications (reducing already scarce resources in taking care of our ...
  • Off target or wrong target 
    Van Zyl, Danie G. (Clinics Cardiv, 2008-06)
    No abstract available
  • HCV genotype 5 : epidemiology and spread of an uncommon genotype 
    Verbeeck, J.; Peigue-Lafeuille, H.; Ross, R.S.; Abergel, A.; Nevens, Frederik; Van der Merwe, Schalk Willem; Van Ranst, Marc; Henquell, C. (Elsevier, 2008-02)
  • Diagnosis and treatment of diabetic ketoacidosis 
    Van Zyl, Danie G. (Medpharm Publishers, 2008-01)
    Diabetic ketoacidosis (DKA) is the most frequent hyperglycaemic acute diabetic complication. Furthermore it carries a significant risk of death, which can be prevented by early and effective management. All physicians, ...
  • Mechanical ventilation in the emergency department 
    Engelbrecht, Andreas; Tintinger, Gregory Ronald (Health and Medical Publishing Group, 2007-03)
    An increasing number of critically ill patients need to be managed in emergency departments worldwide. Numerous theories have attempted to explain the growing number of critically ill patients presenting to emergency ...
  • Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting 
    Van der Merwe, Schalk Willem; Conradie, Maria M.; Bond, Robert P.; Olivier, Brenda J.; Fritz, Elongo Lekunze; Nieuwoudt, Martin J.; Delport, Rhena; Slavik, Tomas; Engelbrecht, Gert H.C.; Kahn, Del; Shephard, Enid G.; Kotze, Maritha J.; De Villiers, Nico P.; Hough, Stephen (WJG Press, 2006-07)
    Please refer to abstract in article
  • Frequency of the metabolic syndrome in screened South African corporate executives 
    Ker, James A.; Rheeder, Paul; Van Tonder, R. (Clinics Cardiv, 2007-01)
    The aim of the study was to determine the frequency of the metabolic syndrome in a specific group of people. The ATP III criteria were used to identify the metabolic syndrome in a group of 1 410 corporate executives belonging ...
  • Absence of Helicobacter pylori within the oral cavities of members of a healthy South African community 
    Olivier, Brenda J.; Bond, Robert P.; Van Zyl, Walda B.; Delport, Maraliese; Slavik, Tomas; Ziady, Christopher; Terhaar sive Droste, Jochim S.; Lastovica, Albert; Van der Merwe, Schalk Willem (American Society for Microbiology, 2006-02)
    Our study aimed to evaluate the oral cavity as a reservoir from where Helicobacter pylori may be transmitted. Histology and PCR amplification were performed. Eighty-four percent of the stomach biopsies tested positive; ...
  • Management issues in hypertensive diabetics 
    Ker, James A. (2006-11)
    This article discusses seven issues in the management of hypertension in diabetic patients, namely the importance of blood pressure control, optimal blood pressure control levels, the importance of blocking the renin-angiotensin ...
  • Glycation of fibrinogen in uncontrolled diabetic patients and the effects of glycaemic control on fibrinogen glycation 
    Pieters, Marlien; Van Zyl, Danie G.; Rheeder, Paul; Jerling, Johann C.; Loots, Du Toit; Van der Westhuizen, Francois Hendrikus; Gottsche, Louise T.; Weisel, John W. (Elsevier, 2007)
    Evidence exists for a relationship between glycaemic control and macrovascular disease. Non-enzymatic glycation of proteins may explain this relationship in part. We investigated the effect of blood glucose control, under ...