General medicine discipline for specialist physicians.
Subdisciplines exist e.g. Gastroenterology, Pulmonology,
Nephrology, Rheumatology and Endocrinology.
BACKGROUND : The framing of teenage pregnancy in social discourse influences the way in which adolescent girls and young women (AGYW) are treated, the extent to which they are supported, and to which they are able to engage ...
Mmakola, Khomotso Madimetsa Shelboy; Balmith, Marissa [; Steel, Helen C.; Said, Mohamed; Potjo, Moliehi; Van der Mescht, Mieke Adri; Hlatshwayo, Nomsa; Meyer, Pieter Willem Adriaan; Tintinger, Gregory Ronald; Anderson, Ronald; Cholo, Moloko C.(MDPI, 2024-12-04)
Multidrug-resistant tuberculosis (MDR-TB) patients are treated with a standardised, short
World Health Organization (WHO) regimen which includes clofazimine (CFZ) and bedaquiline
(BDQ) antibiotics. These two antibiotics ...
Van der Mescht, Mieke Adri; Steel, Helen C.; De Beer, Zelda; Masenge, Andries; Abdullah, Fareed; Ueckermann, Veronica; Anderson, Ronald; Rossouw, Theresa M.(MDPI, 2024-11)
Whether SARS-CoV-2 infection leads to a higher mortality and morbidity in people living
with HIV (PLWH) in Africa remains inconclusive. In this study, we explored the differences in the
T-cell phenotypes between people ...
The first description of sudden cardiac death was made by Hippocrates in the 4‘th century BC1. Such cases of sudden collapse
and death has intrigued both the public and medical science for centuries and a practical ...
BACKGROUND: Given that South Africa has one of the highest rates of pregnancy amongst adolescent girls and
young women (AGYW) globally, the provision of contraceptives to this group has been a key focus in recent ...
Idiopathic inflammatory myositis (IIM) is an expanding field in rheumatology as more myositis-specific antibodies (MSAs) and myositis-associated antibodies (MAAs) become available for testing. Clinical signs and specific ...
Pancreatic cancer (PCa) is acknowledged as a significant contributor to global cancer- related mortality and is widely recognized as one of the most challenging malignant diseases to treat. Pancreatic ductal adenocarcinoma ...
Spontaneous pneumomediastinum is a rare complication in anti–melanoma differentiation associated gene 5 (MDA 5) dermatomyositis (DM). In this case, it occurred relatively early in the course of this patient's illness before ...
INTRODUCTION : Esophageal cancer (EC) is the ninth most common cancer and the sixth leading cause of cancer deaths worldwide. More than 80% of cases and deaths from EC occur within developing countries. In Kenya, cancer ...
BACKGROUND : As mortality declined significantly during the fourth and fifth waves compared to previous waves, the question of the future role of COVID-19 vaccination arose among both experts and the public in South Africa. ...
BACKGROUND : Studies have focused on smoking and alcohol as risk factors for colorectal cancer
(CRC). Caucasians and other populations have been studied worldwide, and both smoking
and alcohol have been validated as ...
Cannabis use is legalised in many countries. We present a patient in their 40s who complained of recurrent abdominal pain and associated nausea and vomiting. The patient was previously seen in various hospitals, treated ...
Johnstone, Siobhan; Erasmus, Linda; Thomas, Juno; Groome, Michelle J.; Du Plessis, Nicolette Marie; Avenant, Theunis Johannes; De Villiers, Maryke; Page, N.A. (Nicola)(Public Library of Science, 2023-09-08)
Diarrhoea is a recognised complication of HIV-infection, yet there are limited local aetiological
data in this high-risk group. These data are important for informing public health interventions
and updating diagnostic ...
Muchiri, Jane Wanjiku; Gericke, Gerda J.; Rheeder, Paul(NISC (Pty) Ltd and Informa UK Limited (trading as the Taylor & Francis Group), 2024)
AIM :
The purpose of this study was to investigate how a randomised controlled trial (RCT) of an adapted diabetes nutrition education programme (NEP) was received by adults with sub-optimally controlled (HbA1c of ≥ 8%) ...
Richardson, Simone I.; Mzindle, Nonkululeko; Motlou, Thopisang; Manamela, Nelia; Van der Mescht, Mieke Adri; Lambson, Bronwen E.; Everatt, Josie; Amoako, Daniel Gyamfi; Balla, Sashkia; Von Gottberg, Anne; Wolter, Nicole; De Beer, Zelda; De Villiers, Talita Roma; Bodenstein, Annie; Van den Berg, Gretha; Abdullah, Fareed; Rossouw, Theresa M.; Boswell, M.T.; Ueckermann, Veronica; Bhiman, Jinal N.; Moore, Penny L.(American Society for Microbiology, 2024-07)
SARS-CoV-2 variants of concern (VOCs) differentially trigger neutralizing and antibody-dependent cellular cytotoxic (ADCC) antibodies with variable cross-reactivity. Omicron BA.4/5 was approved for inclusion in bivalent ...
Ngassa Piotie, Patrick; Webb, Elizabeth M.; Rheeder, Paul(NISC (Pty) Ltd, Medpharm Publications, and Informa UK Limited, 2024)
BACKGROUND :
The management of people living with type 2 diabetes (T2D) in primary care in a South African district was audited, focusing on glycaemic, cholesterol, and blood pressure (BP) control to identify gaps in ...
Ally, Raihaan M.; Van Zyl, Danie G.(NISC (Pty) Ltd, Medpharm Publications, and Informa UK Limited, 2024)
BACKGROUND : Diabetes mellitus (DM) affects millions of people worldwide, with associated morbidity and premature mortality exacerbated by all forms of smoking. The effects of smokeless tobacco, such as snuff and chewing ...
Van der Mescht, Mieke Adri; De Beer, Zelda; Steel, Helen C.; Anderson, Ronald; Masenge, Andries; Moore, Penny L.; Bastard, Paul; Casanova, Jean-Laurent; Abdullah, Fareed; Ueckermann, Veronica; Rossouw, Theresa M.(Elsevier, 2024-09)
The African continent reported the least number of COVID-19 cases and deaths of all the continents, although the exact reasons for this are still unclear. In addition, little is known about the immunological profiles ...
BACKGROUND :
Self-monitoring of glucose is an essential component of type 1 diabetes (T1D) management. In recent years, continuous glucose monitoring (CGM) has provided an alternative to daily fingerstick testing for ...