General medicine discipline for specialist physicians.
Subdisciplines exist e.g. Gastroenterology, Pulmonology,
Nephrology, Rheumatology and Endocrinology.
Spontaneous pneumomediastinum is a rare complication in anti–melanoma differentiation associated gene 5 (MDA 5) dermatomyositis (DM). In this case, it occurred relatively early in the course of this patient's illness before ...
INTRODUCTION : Esophageal cancer (EC) is the ninth most common cancer and the sixth leading cause of cancer deaths worldwide. More than 80% of cases and deaths from EC occur within developing countries. In Kenya, cancer ...
BACKGROUND : As mortality declined significantly during the fourth and fifth waves compared to previous waves, the question of the future role of COVID-19 vaccination arose among both experts and the public in South Africa. ...
BACKGROUND : Studies have focused on smoking and alcohol as risk factors for colorectal cancer
(CRC). Caucasians and other populations have been studied worldwide, and both smoking
and alcohol have been validated as ...
Cannabis use is legalised in many countries. We present a patient in their 40s who complained of recurrent abdominal pain and associated nausea and vomiting. The patient was previously seen in various hospitals, treated ...
Johnstone, Siobhan; Erasmus, Linda; Thomas, Juno; Groome, Michelle J.; Du Plessis, Nicolette Marie; Avenant, Theunis Johannes; De Villiers, Maryke; Page, N.A. (Nicola)(Public Library of Science, 2023-09-08)
Diarrhoea is a recognised complication of HIV-infection, yet there are limited local aetiological
data in this high-risk group. These data are important for informing public health interventions
and updating diagnostic ...
Muchiri, Jane Wanjiku; Gericke, Gerda J.; Rheeder, Paul(NISC (Pty) Ltd and Informa UK Limited (trading as the Taylor & Francis Group), 2024)
AIM :
The purpose of this study was to investigate how a randomised controlled trial (RCT) of an adapted diabetes nutrition education programme (NEP) was received by adults with sub-optimally controlled (HbA1c of ≥ 8%) ...
Richardson, Simone I.; Mzindle, Nonkululeko; Motlou, Thopisang; Manamela, Nelia; Van der Mescht, Mieke Adri; Lambson, Bronwen E.; Everatt, Josie; Amoako, Daniel Gyamfi; Balla, Sashkia; Von Gottberg, Anne; Wolter, Nicole; De Beer, Zelda; De Villiers, Talita Roma; Bodenstein, Annie; Van den Berg, Gretha; Abdullah, Fareed; Rossouw, Theresa M.; Boswell, M.T.; Ueckermann, Veronica; Bhiman, Jinal N.; Moore, Penny L.(American Society for Microbiology, 2024-07)
SARS-CoV-2 variants of concern (VOCs) differentially trigger neutralizing and antibody-dependent cellular cytotoxic (ADCC) antibodies with variable cross-reactivity. Omicron BA.4/5 was approved for inclusion in bivalent ...
Ngassa Piotie, Patrick; Webb, Elizabeth M.; Rheeder, Paul(NISC (Pty) Ltd, Medpharm Publications, and Informa UK Limited, 2024)
BACKGROUND :
The management of people living with type 2 diabetes (T2D) in primary care in a South African district was audited, focusing on glycaemic, cholesterol, and blood pressure (BP) control to identify gaps in ...
Ally, Raihaan M.; Van Zyl, Danie G.(NISC (Pty) Ltd, Medpharm Publications, and Informa UK Limited, 2024)
BACKGROUND : Diabetes mellitus (DM) affects millions of people worldwide, with associated morbidity and premature mortality exacerbated by all forms of smoking. The effects of smokeless tobacco, such as snuff and chewing ...
Van der Mescht, Mieke Adri; De Beer, Zelda; Steel, Helen C.; Anderson, Ronald; Masenge, Andries; Moore, Penny L.; Bastard, Paul; Casanova, Jean-Laurent; Abdullah, Fareed; Ueckermann, Veronica; Rossouw, Theresa M.(Elsevier, 2024-09)
The African continent reported the least number of COVID-19 cases and deaths of all the continents, although the exact reasons for this are still unclear. In addition, little is known about the immunological profiles ...
BACKGROUND :
Self-monitoring of glucose is an essential component of type 1 diabetes (T1D) management. In recent years, continuous glucose monitoring (CGM) has provided an alternative to daily fingerstick testing for ...
INTRODUCTION: Maternally inherited diabetes and deafness (MIDD) is caused by the m.3243A>G pathogenic variant in maternally inherited mitochondrial DNA. Diabetes is prevalent in our setting; however, MIDD is rarely diagnosed. ...
Ker, James A.; Outhoff, Kim(Medpharm Publications, 2023)
This article outlines the principles of blood pressure, including normal and dysfunctional physiology, mathematical equations of pressure,
definitions of hypertension and diagnosis, and hence the rationale for and mechanisms ...
Van Hougenhouck-Tulleken, W.G. (Wesley)(Medpharm Publications, 2023)
Anaemia, occurring in over 50% of patients with stages 3 to 5 chronic kidney disease (CKD), often causes fatigue, shortness of breath, cardiac
dysfunction and cognitive impairment. The major causes include disorders of ...
Ahmed, Marwan Awad; Bailey, Helen D.; Pereira, Gavin; White, Scott W.; Wong, Kingsley; McNamara, Bridgette J.; Rheeder, Paul; Marriott, Rhonda; Shepherd, Carrington C.J.(Oxford University Press, 2023-10)
BACKGROUND :
Aboriginal and Torres Strait Islander (hereafter Aboriginal) women have a high prevalence of diabetes in pregnancy (DIP), which includes pre-gestational diabetes mellitus (PGDM) and gestational diabetes ...
Van der Mescht, Mieke Adri; Steel, Helen C.; De Beer, Zelda; Abdullah, Fareed; Ueckermann, Veronica; Anderson, Ronald; Rossouw, Theresa(Frontiers Media, 2023-08-14)
INTRODUCTION : SARS-CoV-2 elicits a hyper-inflammatory response that
contributes to increased morbidity and mortality in patients with COVID-19. In
the case of HIV infection, despite effective anti-retroviral therapy, ...
The kinetics of Fc-mediated functions following SARS-CoV-2 infection or
vaccination in people living with HIV (PLWH) are not known. We compared
SARS-CoV-2 spike-specific Fc functions, binding, and neutralization in ...
Richards, G.A.; Theron, Annette J.; Van den Bout, Jan Iman; Anderson, Ronald; Feldman, Charles; Van Zyl Smit, Richard; Chang, Ju-Wei; Tintinger, Gregory(European Respiratory Society, 2023-05)
BACKGROUND : Electronic cigarettes (ECs) are electronic aerosol delivery systems composed of nicotine and
various chemicals, which are widely used to facilitate smoking cessation. Although ECs are considered
safer than ...
A 56-year-old woman presented with a 2-year history of
chronic persistent right upper quadrant abdominal pain that
was associated with intermittent nausea, vomiting, and
unintentional weight loss. She had been on ...