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Paediatrics and Child Health: Recent submissions

  • Exclusion diets and challenges in the diagnosis of food allergy 
    Lang, A.C.; Manjra, Ahmed I.; Terblanche, Alta J.; Risenga, Samuel Malamulele; Gray, Claudia L.; Goddard, E.; Karabus, S.; Kriel, M.; Van der Spuy, D.A.; Levin, M.E. (Health and Medical Publishing Group, 2015-01)
    Instituting an exclusion diet for 2 - 6 weeks, and following it up with a planned and intentional re-introduction of the diet, is important for the diagnosis of a food allergy when a cause-and-effect relationship between ...
  • Elimination diets and dietary interventions for the management of food allergies 
    Lang, A.C.; Van der Spuy, D.A.; Goddard, E.; Terblanche, Alta J.; Kriel, M.; Gray, Claudia L.; Karabus, S.; Manjra, Ahmed I.; Risenga, Samuel Malamulele; Levin, M.E. (Health and Medical Publishing Group, 2015-01)
    The primary therapy for food allergy is strict avoidance of the offending food or foods. Dietary restriction should be tailored to meet the nutritional requirements of each patient. Patients should be educated on how to ...
  • Diagnosis of food allergy : history, examination and in vivo and in vitro tests 
    Van der Spuy, D.A.; Terblanche, Alta J.; Karabus, S.; Kriel, M.; Manjra, Ahmed I.; Goddard, E.; Gray, Claudia L.; Lang, A.C.; Risenga, Samuel Malamulele; Levin, M.E. (Health and Medical Publishing Group, 2015-01)
    One cannot depend on one single test to diagnose food allergy. A detailed history is an essential initial step in cases of suspected food allergy. Aspects of the history should be gathered separately for each food being ...
  • Fever in children : how to minimise risk and provide appropriate therapy 
    Green, Robin J.; Pentz, Adele (Medpharm, 2014)
    The management of fever in children is a subject that garners many different opinions and interventions. Various approaches seem to be acceptable, from the physician who never uses antipyretic medication, to the use of ...
  • Missing HIV prevention opportunities in South African children - a 7-year review 
    Feucht, Ute Dagmar; Meyer, Anell; Kruger, Mariana (BioMed Central, 2014-12)
    BACKGROUND : The prevention of mother-to-child transmission (PMTCT) program in South Africa is now successful in ensuring HIV-free survival for most HIV-exposed children, but gaps in PMTCT coverage remain. The study ...
  • Retinoblastoma outcome at a single institution in South Africa 
    Kruger, Mariana; Reynders, David; Omar, Fareed E.; Schoeman, Judy; Wedi, Opope Oyaka; Harvey, J. (South African Medical Journal, 2014-12)
    INTRODUCTION : Retinoblastoma (RB) is the most common eye cancer in children. Early detection is necessary for cure. OBJECTVE : To compare stage and outcome of children with RB treated at Kalafong Hospital, Pretoria, ...
  • Atopic dermatitis - prevention and education of patients 
    Green, Robin J.; Pentz, Adele (Allergy Society of South Africa, 2014-06)
    Why an article on prevention of atopic dermatitis and education of patients and their families? Well one might consider these two topics the two extremes of management of patients at risk from, or with, the condition. A ...
  • Allergic rhinitis in South Africa – Update 2014 
    Green, Robin J.; Hockman, Maurice; Friedman, Raymond; Davis, Martin; Hawarden, Di; Van Rooyen, Cathy; Vardas, Eftyxia; Els, Carla; Feldman, Charles; Levin, Michael; McDonald, Marinda; Bouwer, Stefaan; Tunguy-Desmarais, G. Peter; McCulloch, Alan; Lewis, Humphrey; Hunt, Ian; Wolff, Lionel; Mokgoadi, Fred; Gill, Martin; Jooma, Farouk; Manjra, Ahmed I.; Moodley, Teshni; Jeena, Prakash M.; Joyce, Gustav J.; Seedat, Riaaz; Potter, Paul; Pentz, Adele (Allergy Society of South Africa, 2014-12)
    The SAARWG met on the 8th and 9th February 2014 to discuss and review important concepts in allergic rhinitis diagnosis and management. The theme of that meeting was to lead clinicians through the ideal „Allergy Clinic‟ ...
  • Education and specialist referral of patients with atopic dermatitis 
    Green, Robin J.; Pentz, Adele; Jordaan, H.F. (Health and Medical Publishing Group, 2014-10)
    Educating patients with atopic dermatitis is an essential and necessary part of therapy and particularly important when young children are involved. Quality of life is seriously impaired if patients or their carers do not ...
  • Diagnosis of atopic dermatitis : from bedside to laboratory 
    Sinclair, Werner; Aboobaker, J.; Green, Robin J.; Levin, M.E. (Health and Medical Publishing Group, 2014-10)
    Atopic dermatitis (AD) is essentially diagnosed clinically. In babies and young children, the diagnosis is usually straightforward. Dry, very pruritic dermatitis starts on the cheeks, with the neck and trunk often involved, ...
  • General approach to and summary of the guideline for the management of atopic dermatitis 
    Green, Robin J.; Sinclair, Werner (Health and Medical Publishing Group, 2014-10)
    General approach to and summary of the guideline for the management of atopic dermatitis
  • Topical and systemic pharmacological treatment of atopic dermatitis 
    Puterman, A.; Lewis, Humphrey; Sinclair, Werner; Green, Robin J. (Health and Medical Publishing Group, 2014-10)
    Topical corticosteroids (TCSs) continue to be the mainstay of atopic dermatitis (AD) treatment. For more than four decades TCSs have provided effective flare control by means of their anti-inflammatory, antiproliferative, ...
  • Non-pharmacological treatment modalities for atopic dermatitis 
    Todd, G.; Manjra, Ahmed I.; Sinclair, Werner; Levin, Michael; Green, Robin J. (Health and Medical Publishing Group, 2014-10)
    Non-pharmacological measures to improve the management of atopic dermatitis (AD) are as important as pharmacotherapy for true healing of the skin. Skin dryness (which contributes to inflammation, loss of suppleness (leading ...
  • 3-Methylglutaconic aciduria-lessons from 50 genes and 977 patients 
    Wortmann, Saskia B.; Kluijtmans, Leo A. J.; Rodenburg, Richard J.; Sass, Jörn Oliver; Nouws, Jessica; Van Kaauwen, Edwin P.; Kleefstra, Tjitske; Tranebjaerg, Lisbeth; De Vries, Maaike C.; Isohanni, Pirjo; Walter, Katharina; Alkuraya, Fowzan S.; Smuts, Izelle; Reinecke, Carolus J.; Van der Westhuizen, Francois Hendrikus; Thorburn, David; Smeitink, Jan A.M.; Morava, Eva; Wevers, Ron A. (Springer, 2013-11)
    Elevated urinary excretion of 3-methylglutaconic acid is considered rare in patients suspected of a metabolic disorder. In 3-methylglutaconyl-CoA hydratase deficiency (mutations in AUH), it derives from leucine degradation. ...
  • Atopic dermatitis 
    Sinclair, Werner; Green, Robin J. (Health and Medical Publishing Group, 2014-10)
    The articles in this issue of CME reflect the views of a number of individuals who developed the guideline for the management of atopic dermatitis (AD) to improve the outcome of its treatment in South Africa (SA). AD has ...
  • Aetiopathogenesis of atopic dermatitis 
    Jordaan, H.F.; Todd, G.; Sinclair, Werner; Green, Robin J. (Health and Medical Publishing Group, 2014-10)
    The aetiopathogenesis of atopic dermatitis (AD) is complex and during recent years much has been learnt regarding the genetic predisposition to the development of this condition and how its interaction with the environment ...
  • Candida perforation of the intestine in an HIV exposed but uninfected infant 
    Hoffmann, Kelly S.; Green, Robin J. (Health and Medical Publishing Group, 2014-09)
    BACKGROUND. Oral and nappy Candida infections are common in neonates and infants, but candidaemia and its consequences are more often seen in children with risk factors for immunosuppression. This case presentation ...
  • Management of severe aortic valve stenosis in the neonate 
    Mitchell, Belinda J.; Brown, S.C. (South African Heart Association, 2014)
    Aortic valve stenosis (AS) causing obstruction to the left ventricular outfl ow, and hence reduction of the cardiac output, remains a therapeutic challenge for paediatric cardiologists and cardiothoracic surgeons. Infants ...
  • Biotransformation : can we apply this to allergy and immunology? 
    Els, Carla (Allergy Society of South Africa, 2014-03)
    During medical training all doctors are taught the importance of the cytochrome P450 (CYP) system and the detoxification functions of the liver. An important challenge for pharmaceutical companies is launching new pharmaceutical ...
  • Dealing with spirometry in children under six years of age : challenges and opportunities in asthmatics 
    De Campos, Katya; Masekela, Refiloe (Allergy Society of South Africa, 2014-03)
    Pulmonary function tests are essential in the diagnosis of asthma but these are seldom performed in preschool children. Although pulmonary function tests are critical to the diagnosis and follow up of asthmatics, there ...