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Paediatrics and Child Health: Recent submissions

  • Lung function decline is accelerated in South Africans with cystic fibrosis 
    Masekela, Refiloe; Olorunju, S.; Green, Robin J.; Magidimisa, N.T. (MedPharm Publications, 2016)
    BACKGROUND : Poor nutritional status has been shown to be associated with a significant decline in lung function in patients with cystic fibrosis. There are few data published on the lung function decline and the effects ...
  • South African food allergy consensus document 2014 
    Levin, M.E.; Gray, C.L.; Goddard, E.; Karabus, S.; Kriel, M.; Lang, A.C.; Manjra, A.I.; Risenga, Samuel Malamulele; Terblanche, Alta J.; Van der Spuy, D.A. (Health and Medical Publishing Group, 2015-01)
    The prevalence of food allergy is increasing worldwide and is an important cause of anaphylaxis. There are no local South African food allergy guidelines. This document was devised by the Allergy Society of South Africa ...
  • Food allergy presenting as a surgical abdomen in a neonate 
    Parris, Denise; Green, Robin J. (Allergy Society of South Africa, 2015-12)
    Food allergies, especially of the non-IgE mediated variety, can masquerade as a number of other conditions in the young child. The following case report illustrate how neonate with cow's milk induced enteropathy was ...
  • Heterotaxy syndrome : this is the left, right? 
    Huang, Lili; Mitchell, Belinda J.; Andronikou, Savvas; Lockhat, Zarina I.; Suleman, Farhana Ebrahim (Health and Medical Publishing Group, 2015-12-09)
    Heterotaxy syndrome is a rare and complex disorder of the chest and abdominal organ arrangements, and presents a diagnostic challenge to the radiologist. This article describes the morphological characteristics of ...
  • A diagnostic approach to recurrent respiratory tract infections in childhood : could it be primary immunodeficiency? 
    Van Niekerk, Andre; Esser, M. (Allergy Society of South Africa, 2015-12)
    The recurrence of respiratory tract infections is a common problem in paediatric practice. Parental concerns around recurrent respiratory infections (RRTI) contribute significally towards doctor visits. This a a surprising ...
  • Adherence to case management guidelines of integrated management of childhood illness (IMCI) by healthcare workers in Tshwane, South Africa 
    Mulaudzi, M.C. (Mphelekedzeni) (Health and Medical Publishing Group, 2015-08)
    BACKGROUND. Integrated Management of Childhood Illness (IMCI) is an essential strategy known to deliver childhood interventions that reduce the under-five mortality rate. Objective. To evaluate the adherence to the IMCI ...
  • How ready are our health systems to implement prevention of mother to child transmission Option B+? 
    Nkomo, Palesa; Davies, Natasha; Sherman, Gayle; Bhardwaj, Sanjana; Ramokolo, Vundli; Ngandu, Nobubelo Kwanele; Noveve, Nobuntu; Ramraj, Trisha; Magasana, Vuyolwethu; Singh, Yages; Nsibande, Duduzile Faith; Goga, Ameena Ebrahim (2015-10-07)
    In January 2015, the South African National Department of Health released new consolidated guidelines for the prevention of mother to child transmission (PMTCT) of HIV, in line with the World Health Organization’s (WHO) ...
  • Acute kidney injury in children – not just for the nephrologist 
    Choopa, M.S.; Van Biljon, Gertruida (Medpharm Publications, 2015)
    Acute kidney injury (AKI) is a condition that is characterised by an abrupt reduction in kidney function, and is not limited to acute renal failure. However, it is potentially treatable. Failure to do so may result in ...
  • The 5 x 5 plan for asthma control : the green route to asthma control 
    Green, Robin J. (Medpharm Publications, 2015)
    Apart from medication to control asthmatic inflammation, the education of patients and parents is the most important therapeutic step in achieving asthma control and normal life. This is a critical, but sadly often ...
  • Understanding the implications of mitochondrial DNA variation in the health of black Southern African populations : the 2014 workshop 
    Van der Westhuizen, Francois; Sinxadi, Phumla Z.; Dandara, Collett; Smuts, Izelle; Riordan, Gillian; Meldau, Surita; Malik, Afshan N.; Sweeney, Mary G.; Tsai, Yuchia; Towers, Gordon W.; Louw, Roan; Gorman, Grainne S.; Payne, Brendan; Soodyall, Himla; Pepper, Michael Sean; Elson, Joanna L. (Wiley, 2015-05)
    Knowledge concerning the prevalence and severity of disease related to/associated with variations in mitochondrial DNA (mtDNA) in Black African populations lags behind that of other groups from a global perspective. ...
  • Untargeted urine metabolomics reveals a biosignature for muscle respiratory chain deficiencies 
    Venter, Leonie; Lindeque, Zander; Jansen van Rensburg, Peet; Van der Westhuizen, Francois; Smuts, Izelle; Louw, Roan (Springer, 2015-02)
    Mitochondrial diseases are a heterogeneous group of disorders characterised by impaired mitochondrial oxidative phosphorylation system. Most often for mitochondrial disease, where no metabolic diagnostic biomarkers exist, ...
  • Effects of early feeding on growth velocity and overweight/obesity in a cohort of HIV unexposed South African infants and children 
    Ramokolo, Vundli; Lombard, Carl; Chhagan, Meera; Engebretsen, Ingunn M.S.; Doherty, Tanya; Goga, Ameena Ebrahim; Fadnes, Lars Thore; Zembe, Wanga; Jackson, Debra J.; Van den Broeck, Jan (BioMed Central, 2015-04)
    BACKGROUND : South Africa has the highest prevalence of overweight/obesity in Sub-Saharan Africa. Assessing the effect of modifiable factors such as early infant feeding on growth velocity and overweight/obesity is ...
  • The interaction between respiratory allergies and infection 
    Green, Robin J. (Allergy Society of South Africa, 2015-09)
    The link between allergy and infection, or the microbial world, is receiving world-wide attention. Infectious organisms may play a role in allergy prevention, but some organisms have been linked to the causation of atopic ...
  • Early diagnosis is critical to ensure good outcomes in HIV-infected children : outlining barriers to care 
    Feucht, Ute Dagmar; Meyer, Anell; Thomas, Winifred Nancy; Forsyth, Brian William Cameron; Kruger, Mariana (Routledge, 2016)
    HIV-infected children require early initiation of antiretroviral therapy (ART) to ensure good outcomes. The aim was to investigate missed opportunities in childhood HIV diagnosis leading to delayed ART initiation. Baseline ...
  • The bronchiolitis season is upon us – recommendations for the management and prevention of acute viral bronchiolitis 
    Zar, Heather J.; White, D.A.; Morrow, B.M.; Feldman, Charles; Risenga, Samuel Malamulele; Masekela, Refiloe; Lewis, Humphrey; Jeena, Prakash M.; Madhi, Shabir A. (Health and Medical Publishing Group, 2015-07)
    Despite being so common, bronchiolitis remains poorly diagnosed and managed. This article is intended as an update on issues pertaining to this condition.
  • Nutritional support of children with chronic liver disease 
    Nel, E.D.; Terblanche, Alta J. (Health and Medical Publishing Group, 2015-07)
    Anorexia, malabsorption and metabolic derangements contribute to the malnutrition that occurs in most children with chronic liver disease. Nutritional support should be started early in the management of these children ...
  • Prevalence of Blomia tropicalis allergy in two regions of South Africa 
    Jeevarathnum, A.C.; Van Niekerk, Andre; Green, Robin J.; Becker, P.; Masekela, Refiloe (Health and Medical Publishing Group, 2015-07)
    BACKGROUND. Asthma and allergic rhinitis affect 15% and 38% of South African (SA) children, respectively. The housedust mite (HDM) is the most significant indoor aeroallergen. Typical HDM species include Dermatophagoides ...
  • Vitamin D deficiency and insufficiency in Africa and the Middle East, despite year-round sunny days 
    Green, Robin J.; Samy, G.; Miqdady, M.S.; El-Hodhod, M.; Akinyinka, O.O.; Saleh, G.; Haddad, J.; Assaedi, S.A.; Mersal, A.Y.; Edris, A.; Salah, M. (Health and Medical Publishing Group, 2015-07)
    Exposure to sunlight, specifically ultraviolet B (UVB), is essential for cutaneous vitamin D synthesis. Despite significant daily sunlight availability in Africa and the Middle East, persons living in these regions are ...
  • Nutrition in toddlers 
    Green, Robin J. (Health and Medical Publishing Group, 2015-07)
    This issue of CME is dedicated to nutrition and malnutrition in young children. It is an important topic in paediatric medicine and child health, because toddlers start feeding independently and lifelong feeding patterns ...
  • The impact of highly active antiretroviral therapy on the burden of bacterial lower respiratory tract infections in children 
    De Campos, Katya; Granga, D.D.; Olorunju, Steve A.S.; Masekela, Refiloe (Health and Medical Publishing Group, 2015-07)
    BACKGROUND. Respiratory diseases are common and associated with significant morbidity and mortality in children. OBJECTIVE. To evaluate the prevalence and outcome of bacterial lower respiratory tract infections (LRTIs) ...