Paediatrics and Child Health: Recent submissions

Now showing items 21-40 of 547

Safety and pharmacokinetics of subcutaneous administration of broadly neutralizing anti-HIV-1 monoclonal antibodies (bNAbs), given to HIV-1 exposed, uninfected neonates and infants : study protocol for a Phase I trial

Goga, Ameena Ebrahim; Ramraj, Trisha; Naidoo, Logashvari; Daniels, Brodie; Matlou, Masefetsane; Chetty, Terusha; Dassaye, Reshmi; Ngandu, Nobubelo; Galli, Laura; Reddy, Tarylee; Seocharan, Ishen; Ndlangamandla, Qondeni; September, Qholokazi; Ngcobo, Nokwanda; Reddy, Mayuri; Cafun‑Naidoo, Tamon; Woeber, Kubashni; Jeenarain, , Nitesha; Imamdin, Rabia; Maharajh, Keshnee; Ramjeth, Ashmintha; Bhengu, Thobile; Clarence, Emma; Van de Perre, Philippe; Tylleskar, Thorkild; Nagot, Nicolas; Moles, Jean-Pierre; Moore, Penny L.; Mkhize, Nonhlanhla N.; Gama, Lucio; Dispinseri, Stefania; Biswas, Priscilla; Scarlatti, Gabriella (BMC, 2024-07)

BACKGROUND: The ambitious goal to eliminate new pediatric HIV infections by 2030 requires accelerated prevention strategies in high-risk settings such as South Africa. One approach could be pre-exposure prophylaxis (PrEP) ...
Dr Spur’s mystery solved : COVID diagnosed in a patient with type 1 diabetes. Medicine for that will help the sugar go down

Nagel, Lizelle; Van den Berg, Sylvia; Van Niekerk, Andre (Allergy Society of South Africa, 2023)

Will a spoonful of medicine help the sugar go down?
Causation of term perinatal hypoxic-ischaemic basal ganglia and thalamus injury in the context of cerebral palsy litigation : position statement

Bhorat, Ismail; Buchmann, E.; Frank, K.; Soma-Pillay, Priya; Nicolaou, E.; Pistorius, L.; Smuts, Izelle (Health and Medical Publishing Group, 2023-09)

Basal ganglia and thalamus (BGT) hypoxic-ischaemic brain injury is currently the most contentious issue in cerebral palsy (CP) litigation in South Africa (SA), and merits a consensus response based on the current available ...
SACCSG HL-2018. Barriers and enablers of a harmonized treatment protocol for childhood and adolescent Hodgkin lymphoma in South Africa

Geel, Jennifer; Hendricks, Marc; Goga, Yasmin; Neethling, Beverley; Netshituni, Vutshilo; Mathew, Rema; Vermeulen, Johani; Van Zyl, Anel; Omar, Fareed E.; Du Plessis, Jan; Du Plessis, Liezl; Madzhia, Elelwani; Ngcana, Thandeka; Naidoo, Thanushree; Louw, Lizette; Ballot, Daynia E.; Metzger, Monika L. (Taylor and Francis, 2024)

INTRODUCTION : Collaborative studies have contributed to improved survival of pediatric Hodgkin lymphoma in well-resourced settings, but few are documented in resource-constrained countries. The South Africa Children’s ...
The prevalence and spectrum of thyroid dysfunction among children with Down syndrome attending the paediatric services at two tertiary hospitals in Pretoria, South Africa

Maphumulo, S.F.; Honey, E.M. (Engela); Abdelatif, Nada; Karsas, Maria (South African Medical Association, 2023-12)

BACKGROUND : Down syndrome (DS) is the most common chromosomal abnormality in the paediatric setting, and thyroid dysfunction is more commonly encountered in this population than among the general population. The literature ...
The impact of hypothermia in a tertiary hospital neonatal unit

Tshehla, Rosine Marie; Coetzee, Melantha; Becker, Piet J. (South African Medical Association, 2023-12)

BACKGROUND : Neonatal hypothermia, defined as a body temperature <36.5°C, is a known contributor to neonatal morbidity and mortality. The admission temperature is an important predictor of neonatal outcomes, and a measure ...
Response to 'Commentary on the published position statement regarding the pathogenesis of fetal basal ganglia- thalamic hypoxic-ischaemic injury' (Anthony et al.)

Bhorat, I.; Buchmann, E.; Frank, K.; Soma-Pillay, Priya; Nicolaou, E.; Pistorius, L.; Smuts, Izelle (Health and Medical Publishing Group, 2024-01)

No abstract available.
Novel approaches to postnatal prophylaxis to eliminate vertical transmission of HIV

Ruel, Theodore; Penazzato, Martina; Zech, Jennifer M.; Archary, Moherndran; Cressey, Tim R.; Goga, Ameena Ebrahim; Harwell, Joseph; Landovitz, Raphael J.; Lain, Maria Grazia; Lallemant, Marc; Namusoke-Magongo, Eleanor; Mukui, Irene; Permar, Sallie R.; Prendergast, Andrew J.; Shapiro, Roger; Abrams, Elaine J. (Johns Hopkins University Press, 2023-04-03)

No abstract available.
Healthcare-associated infections drive antimicrobial prescribing in pediatric departments at three academic hospitals in South Africa

Chetty, Terusha; Pillay, Ashendri; Balakrishna, Yusentha; Reddy, Tarylee; Goga, Ameena Ebrahim; Moore, David P.; Karsas, Maria; Cloete, Jeane; Archary, Moherndran; Van Kwawegen, Alison; Thomas, Reenu; Nakwa, Firdose Lambey; Waggie, Zainab; Magrath, Stephanie; Jeena, Prakash Mohan (Lippincott Williams and Wilkins, 2023-08)

BACKGROUND : The prevalence of antimicrobial prescriptions for healthcare-associated infections (HAI) in South Africa is largely unknown. This study aimed to estimate the point prevalence of pediatric antibiotic and ...
The pre-surgical factors that determine the decision to proceed to resection in children diagnosed with high-risk neuroblastoma in a resource limited setting

Van Heerden, Jaques; Kruger, Mariana M.; Esterhuizen, Tonya Marianne; Van Zyl, Anel; Hendricks, Marc; Cox, Sharon; Mangray, Hansraj; Poole, Janet; Naidu, Gita; Buchner, Ane; De Villiers, Mariza; Du Plessis, Jan; Van Emmenes, Barry; Matthews, Elmarie; Manickchund, Yashoda; Harrison, Derek Stanley (Taylor and Francis, 2023)

Surgical control has prognostic value in neuroblastoma (NB). Advanced NB is common at diagnosis in South Africa. We investigated the pre-surgery factors that influenced decisions to perform surgical resections. We included ...
Preventing breast milk HIV transmission using broadly neutralizing monoclonal antibodies : one size does not fit all

Van de Perre, Philippe; Scarlatti, Gabriella; Moore, Penny L.; Moles, Jean-Pierre; Nagot, Nicolas; Tylleskar, Thorkild; Gray, Glenda E.; Goga, Ameena Ebrahim (Wiley, 2024-03)

Passive immunoprophylaxis with broadly neutralizing monoclonal antibodies (bNAbs) could be a game changer in the prevention of human immunodeficiency virus (HIV) acquisition. The prevailing view is that available ...
Antibiotic and antifungal use in paediatric departments at three academic hospitals in South Africa

Moore, David P.; Chetty, Terusha; Pillay, Ashendri; Karsas, Maria; Cloete, Jeane; Balakrishna, Yusentha; Reddy, Tarylee; Archary, Moherndran; Van Kwawegen, Alison; Thomas, Reenu; Nakwa, Firdose L.; Waggie, Zainab; Magrath, Stephanie; Goga, Ameena Ebrahim; Jeena, Prakash (Elsevier, 2024-03)

OBJECTIVES : South Africa implemented a National Strategic Framework to optimise antimicrobial stewardship in 2014; however, there is limited data on how this has affected prescribing, especially to children treated in ...
Dr Spur’s mystery case : the pain of the grain

Swanepoel, Petri; Van den Berg, Sylvia; Van Niekerk, Andre (Allergy Society of South Africa, 2023-03)

No abstract available.
Dr Spur's mystery case. Allergy, atopic dermatitis, abnormal FBC and elevated IgE : what do you see?

Teixeira, Miguel Jose; Van den Berg, Sylvia; Van Niekerk, Andre (Allergy Society of South Africa, 2023-12)

No abstract available.
Diagnosing and managing childhood asthma effectively with limited resources

Van Niekerk, Andre; Weinberg, Eugene G. (Allergy Society of South Africa, 2023-03)

Childhood asthma must be diagnosed and managed correctly. It is the most common and potentially fatal chronic noncommunicable disease in children. The prevalence of asthma is increasing in both resource-limited and ...
Mystery case solved : knowing the sentinel organisms associated with IEI can help you with early diagnosis and management

Van den Berg, Sylvia; Swanepoel, Petri; Nagel, Lizelle; Van Niekerk, Andre (Allergy Society of South Africa, 2023-06)

No abstract available.
Metabolic alterations in mothers living with HIV and their HIV-exposed, uninfected infants

Du Toit, Louise de Villiers; Mason, Shayne; Van Reenen, Mari; Rossouw, Theresa; Louw, Roan (MDPI, 2024-02)

HIV-exposed, uninfected (HEU) children present with suboptimal growth and a greater susceptibility to infection in early life when compared to HIV-unexposed, uninfected (HUU) children. The reasons for these findings are ...
Changes in prevalence and seasonality of pathogens identified in acute respiratory tract infections in hospitalised individuals in rural and urban settings in South Africa; 2018–2022

Davids, Michaela; Johnstone, Siobhan; Mendes, Adriano; Brecht, Gadean; Avenant, Theunis Johannes; Du Plessis, Nicolette Marie; De Villiers, Maryke; Page, N.A. (Nicola); Venter, Marietjie (MDPI, 2024-03)

Severe acute respiratory tract infections (SARIs) has been well described in South Africa with seasonal patterns described for influenza and respiratory syncytial virus (RSV), while others occur year-round (rhinovirus and ...
West Nile virus, an underdiagnosed cause of acute fever of unknown origin and neurological disease among hospitalized patients in South Africa

MacIntyre, Caitlin; Lourens, Carla; Mendes, Adriano; De Villiers, Maryke; Avenant, Theunis Johannes; Du Plessis, Nicolette Marie; Leendertz, Fabian; Venter, Marietjie (MDPI, 2023-11-02)

West Nile virus (WNV), a mosquito-borne flavivirus, is endemic to South Africa. However, its contribution to acute febrile and neurological disease in hospitalized patients in South Africa is unknown. This study examined ...
Vascular thrombosis after single dose Ad26.COV2.S vaccine in healthcare workers in South Africa : open label, single arm, phase 3B study (Sisonke study)

Jacobson, Barry Frank; Schapkaitz, Elise; Takalani, Azwi; Rowji, Pradeep; Louw, Vernon Johan; Opie, Jessica; Bekker, Linda‑Gail; Garrett, N.; Goga, Ameena Ebrahim; Reddy, Tarylee; Yende-Zuma, Nonhlanhla; Sanne, Ian; Seocharan, Ishen; Robinson, Michelle; Collie, Shirley; Khan, Amber; Takuva, S.; Gray, Glenda (BMJ Publishing, 2023-03)

OBJECTIVE : To assess the rates of vascular thrombotic adverse events in the first 35 days after one dose of the Ad26.COV2.S vaccine (Janssen/ Johnson & Johnson) in healthcare workers in South Africa and to compare ...

Now showing items 21-40 of 547

Search UPSpace

Browse

All of UPSpace
This Community
- Issue Date
- Authors
- Titles
- Subjects
- Supervisor
- UP Author
- UP Postgraduate
- Type

Recently added

Paediatrics and Child Health: Recent submissions

Search UPSpace

Browse

All of UPSpace

This Community

My Account

UPSpace Workspace