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Paediatrics and Child Health: Recent submissions

  • Dr Spur’s mystery case : monthly fevers? Can you aid me with this family’s grievances? 
    Nagel, Lizelle; Teixeira, Miguel Jose; Van den Berg, Sylvia; Van Niekerk, Andre (Allergy Society of South Africa, 2024-03-01)
    No abstract available.
  • How paediatric HIV services weathered the COVID-19 storm in Tshwane District, South Africa 
    Christie, Michael; Mazanderani, Ahmad Haeri; Sherman, Gayle G.; Feucht, Ute Dagmar (AOSIS, 2024-05-20)
    BACKGROUND : The coronavirus disease 2019 (COVID-19) pandemic disrupted paediatric HIV services across South Africa. Shortly before COVID-19, updated national HIV guidelines were released. OBJECTIVES : This study describes ...
  • Chronic beryllium disease : an unexpected occupational hazard for a jeweller 
    Teixeira, Miguel Jose; Nagel, Lizelle; Plekker, Dante; Van der Merwe, Cassandre; Van den Berg, Sylvia (Allergy Society of South Africa, 2024-09-01)
    Beryllium is used widely in industry due to its favourable elemental properties. Its extraction and subsequent incorporation into alloys and composites generate hazardous fumes and dust. Chronic beryllium disease (CBD) ...
  • Neurological examination of healthy term infants at ages 6 and 10 weeks in Tshwane District 
    Nel, Marna; Feucht, Ute Dagmar; Mulol, Helen; Eksteen, Carina A. (AOSIS, 2024-08-30)
    BACKGROUND : Globally, there is a significant gap in detailed neurodevelopmental data for infants under 3 months, despite 6 weeks being identified a critical milestone for neuro-behavioural development. Normative values ...
  • A swallowing and breastfeeding intervention programme for small and sick neonates embedded in kangaroo mother care 
    Kritzinger, Alta M. (Aletta Margaretha); Van Rooyen, Elise; Bergh, Anne-Marie (AOSIS, 2024-08-09)
    Available evidence of oral sensorimotor interventions for small neonates is not strong. Evidence of interventions for sick term neonates is largely lacking. Studies are limited by risk of bias and inconsistency. Evidence ...
  • Prescribing probiotic drugs in clinical practice - are they indicated? 
    Van Niekerk, Andre; Delport, Suzanne D. (Allergy Society of South Africa, 2024-06-01)
    The past two decades will be remembered for the rapid advances in our understanding of the significant role that the human microbiome plays in health, illness and longevity, but it remains a vast concept, one that is ...
  • Clinical characteristics, pathological features and treatment outcomes of children with nephrotic syndrome at Princess Marina Hospital, Botswana 
    Mosalakatane, Thembisile Dintle; Gottlich, Errol; Mazhani, Loeto; Joel, Dipesalema; Mogotsi, Thabiso Vivien; Arscott-Mills, Tonya (Sage, 2024-07)
    OBJECTIVE : Despite the remarkable progress made in the understanding and treatment of childhood nephrotic syndrome (NS), a lot is still unknown about its epidemiology in many African countries. This study sought to determine ...
  • Outcomes of right ventricular outflow tract stenting as a palliative procedure in tetralogy of Fallot patients 
    Pickup, Victoria; Joshi, Jayneel A. (South African Heart Association, 2024-04)
    BACKGROUND : Certain groups of tetralogy of Fallot (TOF) patients require a palliative procedure until factors permit a full surgical repair. An aorto-pulmonary shunt is the gold standard palliative procedure but requires ...
  • Adolescent maternal mortality at a district health services over a five year period in South Africa : a retrospective study 
    Basu, Jayati Kusari; Stewart, Aimee; Feucht, Ute Dagmar; Wing, Jeffrey; Basu, Debashis (Wiley, 2024)
    OBJECTIVE : To determine the trend in adolescent maternal deaths and deliveries over a period of 5 years and 9 months (July 2014–March 2020) at the Ekurhuleni Health District in South Africa. METHODS : The present ...
  • Implemented nutritional intervention algorithm in pediatric oncology compared to standard nutritional supportive care outcomes 
    Schoeman, Judy; Kellerman, Ilde-Marie; Ladas, Elena J.; Ndlovu, Sandile; Rogers, Paul C.; Du Plessis, Jan; Herholdt, Mariechen; Reynders, David; Naidu, Gita; Rowe, Biance; Thomas, Karla; Vanemmenes, Barry; Mathews, Rema; Buchner, Ane; Omar, Fareed E.; Uys, Ronelle; Kruger, Mariana (Elsevier, 2024-10)
    AIM : To implement a childhood cancer-specific nutritional algorithm adapted for the South African context for interventions at time-set intervals to evaluate differences in the nutritional status of newly diagnosed ...
  • Neuromuscular disease genetics in underrepresented populations : increasing data diversity 
    Wilson, Lindsay A.; Macken, William L.; Perry, Luke D.; Record, Christopher J.; Schon, Katherine R.; Frezatti, Rodrigo S.S.; Raga, Sharika; Naidu, Kireshnee; Köken, Ozlem Yayıcı; Kapapa, Musambo M.; Dominik, Natalia; Efthymiou, Stephanie; Morsy, Heba; Nel, Melissa; Fassad, Mahmoud R.; Gao, Fei; Patel, Krutik; Schoonen, Maryke; Bisschoff, Michelle; Vorster, Armand; Jonvik, Hallgeir; Human, Ronel; Lubbe, Elsabeth (Elsa); Nonyane, Malebo; Vengalil, Seena; Nashi, Saraswati; Srivastava, Kosha; Lemmers, Richard J.L.F.; Reyaz, Alisha; Mishra, Rinkle; Topf, Ana; Trainor, Christina I.; Steyn, Elizabeth C.; Mahungu, Amokelani C.; Van der Vliet, Patrick J.; Ceylan, Ahmet Cevdet; Hiz, A. Semra; Cavdarlı, Bussranur; Gunduz, C. Nur Semerci; Ceylan, Gulay Gulec; Nagappa, Madhu; Tallapaka, Karthik B.; Govindaraj, Periyasamy; Van der Maarel, Silvere M.; Narayanappa, Gayathri; Nandeesh, Bevinahalli N.; Somwe, Wa Somwe; Bearden, David R.; Kvalsund, Michelle P.; Ramdharry, Gita M.; Oktay, Yavuz; Yis, Uluc; Topaloglu, Haluk; Sarkozy, Anna; Bugiardini, Enrico; Henning, Franclo; Wilmshurst, Jo M.; Heckmann, Jeannine M.; McFarland, Robert; Taylor, Robert W.; Smuts, Izelle; Van der Westhuizen, Francois H.; Da Rosa Sobreira, Claudia Ferreira; Tomaselli, Pedro J.; Marques Jr, Wilson; Bhatia, Rohit; Dalal, Ashwin; Srivastava, M.V. Padma; Yareeda, Sireesha; Nalini, Atchayaram; Vishnu, Venugopalan Y.; Thangaraj, Kumarasamy; Straub, Volker; Horvath, Rita; Chinnery, Patrick F.; Pitceathly, Robert D.S.; Muntoni, Francesco; Houlden, Henry; Vandrovcova, Jana; Reilly, Mary M.; Hanna, Michael G. (Oxford University Press, 2023-07)
    Neuromuscular diseases (NMDs) affect ∼15 million people globally. In high income settings DNA-based diagnosis has transformed care pathways and led to gene-specific therapies. However, most affected families are in ...
  • UNITY : a low-field magnetic resonance neuroimaging initiative to characterize neurodevelopment in low and middle-income settings 
    Abate, F.; Adu-Amankwah, A.; Ae-Ngibise, K.A.; Agbokey, F.; Agyemang, V.A.; Agyemang, C.T.; Akgun, C.; Ametepe, J.; Arichi, T.; Asante, K.P.; Balaji, S.; Baljer, L.; Basser, P.J.; Beauchemin, J.; Bennallick, C.; Berhane, Y.; Boateng-Mensah, Y.; Bourke, N.J.; Bradford, L.; Bruchhage, M.M.K.; Cano Lorente, R.; Cawley, P.; Cercignani, M.; D Sa, V.; De Canha, A.; Navarro, N.D.; Dean, D.C., III; Delarosa, J.; Donald, K.A.; Dvorak, A.; Edwards, A.D.; Field, D.; Frail, H.; Freeman, B.; George, T.; Gholam, J.; Guerrero-Gonzalez, J.; Hajnal, J.V.; Haque, R.; Hollander, W.; Hoodbhoy, Z.; Huentelman, M.; Jafri, S.K.; Jones, D.K.; Joubert, Fourie; Karaulanov, T.; Kasaro, M.P.; Knackstedt, S.; Kolind, S.; Koshy, B.; Kravitz, R.; Lafayette, S.L.; Lee, A.C.; Lena, B.; Lepore, N.; Linguraru, M.; Ljungberg, E.; Lockhat, Zarina I.; Loth, E.; Mannam, P.; Masemola, K.M.; Moran, R.; Murphy, D.; Nakwa, F.L.; Nankabirwa, V.; Nelson, C.A.; North, K.; Nyame, S.; O Halloran, R.; O'Muircheartaigh, J.; Oakley, B.F.; Odendaal, H.; Ongeti, C.M.; Onyango, D.; Oppong, S.A.; Padormo, F.; Parvez, D.; Paus, T.; Pepper, Michael Sean; Phiri, K.S.; Poorman, M.; Ringshaw, J.E.; Rogers, J.; Rutherford, M.; Sabir, H.; Sacolick, L.; Seal, M.; Sekoli, M.L.; Shama, T.; Siddiqui, K.; Sindano, N.; Spelke, M.B.; Springer, P.E.; Suleman, Farhana Ebrahim; Sundgren, P.C.; Teixeira, R.; Terekegn, W.; Traughber, M.; Tuuli, M.G.; Van Rensburg, Jeanne; Váša, F.; Velaphi, S.; Velasco, P.; Viljoen, I.M.; Vokhiwa, M.; Webb, A.; Weiant, C.; Wiley, N.; Wintermark, P.; Yibetal, K.; Deoni, S.C.L.; Williams, S.C.R. (Elsevier, 2024-10)
    Measures of physical growth, such as weight and height have long been the predominant outcomes for monitoring child health and evaluating interventional outcomes in public health studies, including those that may impact ...
  • Seroprevalence survey of anti-SARS-CoV-2 antibody and associated factors in South Africa : findings of the 2020–2021 population-based household survey 
    Moyo, Sizulu; Simbayi, Leickness C.; Zuma, Khangelani; Zungu, Nompumelelo Precious; Marinda, Edmore; Jooste, Sean; Ramlagan, Shandir; Fortuin, Mirriam; Singh, Beverley; Mabaso, Musawenkosi; Reddy, Tarylee; Parker, Whadi-ah; Naidoo, Inbarani; Manda, Samuel; Goga, Ameena Ebrahim; Ngandu, Nobubelo; Cawood, Cherie; Moore, Penny L.; Puren, Adrian (Public Library of Science, 2023-09-25)
    Population-based serological testing is important to understand the epidemiology and estimate the true cumulative incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inform public health interventions. ...
  • Epidemiology and aetiology of moderate to severe diarrhoea in hospitalised patients ≥5 years old living with HIV in South Africa, 2018- 2021 : a case-control analysis 
    Johnstone, Siobhan; Erasmus, Linda; Thomas, Juno; Groome, Michelle J.; Du Plessis, Nicolette Marie; Avenant, Theunis Johannes; De Villiers, Maryke; Page, N.A. (Nicola) (Public Library of Science, 2023-09-08)
    Diarrhoea is a recognised complication of HIV-infection, yet there are limited local aetiological data in this high-risk group. These data are important for informing public health interventions and updating diagnostic ...
  • High burden of co-infection with multiple enteric pathogens in children suffering with diarrhoea from rural and peri-urban communities in South Africa 
    Potgieter, Natasha; Heine, Lee; Ngandu, Jean Pierre Kabue; Ledwaba, Solanka Ellen; Zitha, Tinyiko; Mudau, Lutendo Sylvia; Becker, Piet J.; Traore, Afsatou Ndama; Barnard, Tobias George (MDPI, 2023-02-14)
    Infectious diarrhoea contributes to high morbidity and mortality in young children from sub-Saharan Africa. The aim of this study was to assess the prevalence of single and multiple diarrhoeal-causing pathogen combinations ...
  • Infant growth by INTERGROWTH-21st and Fenton Growth Charts : predicting 1-year anthropometry in South African preterm infants 
    Nel, Sanja; Feucht, Ute Dagmar; Botha, Tanita; Wenhold, Friedeburg Anna Maria (Wiley, 2024-10)
    Post-natal growth influences short- and long-term preterm infant outcomes. Different growth charts, such as the Fenton Growth Chart (FGC) and INTERGROWTH-21st Preterm Post-natal Growth Standards (IG-PPGS), describe different ...
  • Comparison of feeding practices and growth of urbanized African infants aged 6–12 months old by maternal HIV status in Gauteng Province, South Africa 
    Tshiambara, Phumudzo; Hoffman, Marinel; Legodi, Heather; Botha, Tanita; Mulol, Helen; Pisa, Pedro Terrence; Feucht, Ute Dagmar (MDPI, 2023-03-21)
    Appropriate feeding practices are protective against malnutrition and poor growth. We compared feeding practices and growth in HIV-exposed-uninfected (HEU) and HIV-unexposeduninfected (HUU) between 6-12 months of age in ...
  • Long-term outcomes in two adult siblings with Fucosidosis – diagnostic odyssey and clinical manifestations 
    Puente-Ruiz, Nuria; Ellis, Ian; Bregu, Marsel; Chen, Cliff; Church, Heather J.; Tylee, Karen L.; Glaston, Shalini; Hackett, Richard; Oldham, Andrew; Virk, Surinder; Hendriksz, Christian J.; Morris, Andrew A.M.; Jones, Simon A.; Stepien, Karolina M. (Elsevier, 2023-12)
    Fucosidosis (OMIN# 230000) is a rare lysosomal storage disorder (LSDs) caused by mutations in the FUCA1 gene, leading to alpha-L-fucosidase deficiency; it is inherited as an autosomal recessive trait. Fucosidosis represents a ...
  • Long-term effect of pneumococcal conjugate vaccines on invasive pneumococcal disease incidence among people of all ages from national, active, laboratory-based surveillance in South Africa, 2005–19 : a cohort observational study 
    Von Gottberg, Anne; Kleynhans, Jackie; De Gouveia, Linda; Tempia, Stefano; Meiring, Susan; Quan, Vanessa; Du Plessis, Mignon; Von Mollendorf, Claire; Crowther-Gibson, Penny; Avenant, Theunis Johannes; Du Plessis, Nicolette Marie; Kularatne, Ranmini; Chibabhai, Vindana; Madhi, Shabir A.; Klugman, Keith P.; Whitney, Cynthia G.; Cohen, Cheryl (Elsevier, 2024-09)
    BACKGROUND : In South Africa, 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in 2009 and 13-valent PCV (PCV13) was introduced in 2011, both in a two plus one schedule. We evaluated the ongoing effects of ...
  • Implementation research : a protocol for two three-arm pragmatic randomised controlled trials on continuous glucose monitoring devices in people with type 1 diabetes in South Africa and Kenya 
    Marban-Castro, Elena; Muhwava, Lorrein; Kamau, Yvonne; Safary, Elvis; Rheeder, Paul; Karsas, Maria; Kemp, Tanja; Freitas, Johane; Carrihill, Michelle; Dave, Joel; Katambo, Daniel; Kimetto, Joan; Allie, Razana; Ndungu, Joseph; Sigwebela, Ntombi; Akach, Dorcas; Girdwood, Sarah; Erkosar, Berra; Nichols, Brooke E.; Haldane, Cathy; Vetter, Beatrice; Shilton, Sonjelle (BMC, 2024-05)
    BACKGROUND : Self-monitoring of glucose is an essential component of type 1 diabetes (T1D) management. In recent years, continuous glucose monitoring (CGM) has provided an alternative to daily fingerstick testing for ...