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Paediatrics and Child Health: Recent submissions

  • Bronchiectasis in children in a high HIV and tuberculosis prevalence setting 
    Juggernath, Pearline; Mopeli, Keketso; Masekela, Refiloe; Dangor, Ziyaad; Goga, Ameena Ebrahim; Gray, Diane M.; Verwey, Charl (South African Medical Association, 2024-12)
    BACKGROUND: Bronchiectasis, a chronic suppurative lung condition, is a largely neglected disease, especially in low- to middle-income countries (LMICs), from which there is a paucity of data. Post-infectious causes are ...
  • Vaccine stock-outs : a preventable health facility obstacle contributing to missed vaccinations in South African children 
    Masemola, Natasha M.; Burnett, Rosemary J.; Makamba-Mutevedzi, Portia C.; Schonfeldt, Marione; Bamford, Lesley; Ismail, Zeenat; Madhi, Shabir A.; Meyer, Johanna C. (Elsevier, 2025-01)
    In 2019 the National Department of Health (NDoH) conducted a national immunisation coverage survey of caregivers of children aged 24–35 months in all 52 districts of South Africa, and reported a national fully immunised ...
  • Vaccine safety surveillance in South Africa through COVID-19 : a journey to systems strengthening 
    Sankar, Chenoa; Meyer, Johanna C.; Schonfeldt, Marione; Gunter, Hannah; Dawood, Halima; Sekiti, Victoria; Pickard, Naseera; Mubaiwa, Lawrence; Mawela, Dini; Dlamini, Sipho; Peter, Jonny; Spencer, David; Gray, Clive; Patel, Vinod; Bamford, Lesley; Sehloho, Tohlang; McCarthy, Kerrigan (Elsevier, 2025-02)
    BACKGROUND : Surveillance systems for monitoring and reporting adverse events following immunisation (AEFI) and adverse events of special interest (AESI) are vital in understanding safety profiles of post-marketed vaccines. ...
  • Dietary intake and growth of HIV exposed and unexposed 6-12 months old infants in South Africa 
    Tshiambara, Phumudzo; Hoffman, Marinel; Legodi, Heather; Balakrishna, Yusentha; Feucht, Ute Dagmar (Wiley, 2025-01)
    Factors affecting the growth of HIV‐exposed‐uninfected (HEU) children are multi‐factorial, with limited information available on the dietary intake from 6 months. This study compared the dietary intake, micronutrient ...
  • Inborn errors of immunity in paediatric neurology 
    Smuts, Izelle; Human, Freda P. (Allergy Society of South Africa, 2024-03)
    Inborn errors of immunity has become a rapidly evolving medical field, with nearly 500 conditions; as a result, the sheer volume of information can be overwhelming. In order to make a sound diagnosis, clinicians must adopt ...
  • One-year anthropometric follow-up of South African preterm infants in kangaroo mother care : which early-life factors predict malnutrition? 
    Nel, Sanja; Wenhold, Friedeburg Anna Maria; Botha, Tanita; Feucht, Ute Dagmar (Wiley, 2024-04)
    BACKGROUND : Preterm infants often have poor short- and long-term growth. Kangaroo mother care supports short-term growth, but longer-term outcomes are unclear. METHODS : This study analysed longitudinally collected ...
  • Neonatal encephalopathy due to suspected hypoxic ischemic encephalopathy : pathophysiology, current, and emerging treatments 
    Babbo, Carina Corte-Real; Mellet, Juanita; Van Rensburg, Jeanette; Pillay, Shakti; Horn, Alan Richard; Nakwa, Firdose Lambey; Velaphi, Sithembiso Christopher; Kali, Gugulabatembunamahlubi Tenjiwe Jabulile; Coetzee, Melantha; Masemola, Mogomane Yvonne Khomotso; Ballot, Daynia Elizabeth; Pepper, Michael Sean (Springer, 2024-11)
    BACKGROUND : Neonatal encephalopathy (NE) due to suspected hypoxic-ischemic encephalopathy (HIE), referred to as NESHIE, is a clinical diagnosis in late preterm and term newborns. It occurs as a result of impaired ...
  • Retention in care of infants diagnosed with HIV at birth : beyond the diagnostic strategy 
    Christie, Michael; Du Plessis, Nicolette Marie (AOSIS, 2024-03-30)
    BACKGROUND : Birth HIV point-of-care (POC) tests curtail analytical testing issues and expedite diagnosis, potentially allowing for earlier mother-infant pair engagement and improved outcomes. Many children are lost post ...
  • Dr Spur’s mystery case : monthly fevers? Can you aid me with this family’s grievances? 
    Nagel, Lizelle; Teixeira, Miguel Jose; Van den Berg, Sylvia; Van Niekerk, Andre (Allergy Society of South Africa, 2024-03-01)
    No abstract available.
  • How paediatric HIV services weathered the COVID-19 storm in Tshwane District, South Africa 
    Christie, Michael; Mazanderani, Ahmad Haeri; Sherman, Gayle G.; Feucht, Ute Dagmar (AOSIS, 2024-05-20)
    BACKGROUND : The coronavirus disease 2019 (COVID-19) pandemic disrupted paediatric HIV services across South Africa. Shortly before COVID-19, updated national HIV guidelines were released. OBJECTIVES : This study describes ...
  • Chronic beryllium disease : an unexpected occupational hazard for a jeweller 
    Teixeira, Miguel Jose; Nagel, Lizelle; Plekker, Dante; Van der Merwe, Cassandre; Van den Berg, Sylvia (Allergy Society of South Africa, 2024-09-01)
    Beryllium is used widely in industry due to its favourable elemental properties. Its extraction and subsequent incorporation into alloys and composites generate hazardous fumes and dust. Chronic beryllium disease (CBD) ...
  • Neurological examination of healthy term infants at ages 6 and 10 weeks in Tshwane District 
    Nel, Marna; Feucht, Ute Dagmar; Mulol, Helen; Eksteen, Carina A. (AOSIS, 2024-08-30)
    BACKGROUND : Globally, there is a significant gap in detailed neurodevelopmental data for infants under 3 months, despite 6 weeks being identified a critical milestone for neuro-behavioural development. Normative values ...
  • A swallowing and breastfeeding intervention programme for small and sick neonates embedded in kangaroo mother care 
    Kritzinger, Alta M. (Aletta Margaretha); Van Rooyen, Elise; Bergh, Anne-Marie (AOSIS, 2024-08-09)
    Available evidence of oral sensorimotor interventions for small neonates is not strong. Evidence of interventions for sick term neonates is largely lacking. Studies are limited by risk of bias and inconsistency. Evidence ...
  • Prescribing probiotic drugs in clinical practice - are they indicated? 
    Van Niekerk, Andre; Delport, Suzanne D. (Allergy Society of South Africa, 2024-06-01)
    The past two decades will be remembered for the rapid advances in our understanding of the significant role that the human microbiome plays in health, illness and longevity, but it remains a vast concept, one that is ...
  • Clinical characteristics, pathological features and treatment outcomes of children with nephrotic syndrome at Princess Marina Hospital, Botswana 
    Mosalakatane, Thembisile Dintle; Gottlich, Errol; Mazhani, Loeto; Joel, Dipesalema; Mogotsi, Thabiso Vivien; Arscott-Mills, Tonya (Sage, 2024-07)
    OBJECTIVE : Despite the remarkable progress made in the understanding and treatment of childhood nephrotic syndrome (NS), a lot is still unknown about its epidemiology in many African countries. This study sought to determine ...
  • Outcomes of right ventricular outflow tract stenting as a palliative procedure in tetralogy of Fallot patients 
    Pickup, Victoria; Joshi, Jayneel A. (South African Heart Association, 2024-04)
    BACKGROUND : Certain groups of tetralogy of Fallot (TOF) patients require a palliative procedure until factors permit a full surgical repair. An aorto-pulmonary shunt is the gold standard palliative procedure but requires ...
  • Adolescent maternal mortality at a district health services over a five year period in South Africa : a retrospective study 
    Basu, Jayati Kusari; Stewart, Aimee; Feucht, Ute Dagmar; Wing, Jeffrey; Basu, Debashis (Wiley, 2024-12)
    OBJECTIVE : To determine the trend in adolescent maternal deaths and deliveries over a period of 5 years and 9 months (July 2014–March 2020) at the Ekurhuleni Health District in South Africa. METHODS : The present ...
  • Implemented nutritional intervention algorithm in pediatric oncology compared to standard nutritional supportive care outcomes 
    Schoeman, Judy; Kellerman, Ilde-Marie; Ladas, Elena J.; Ndlovu, Sandile; Rogers, Paul C.; Du Plessis, Jan; Herholdt, Mariechen; Reynders, David; Naidu, Gita; Rowe, Biance; Thomas, Karla; Vanemmenes, Barry; Mathews, Rema; Buchner, Ane; Omar, Fareed E.; Uys, Ronelle; Kruger, Mariana (Elsevier, 2024-10)
    AIM : To implement a childhood cancer-specific nutritional algorithm adapted for the South African context for interventions at time-set intervals to evaluate differences in the nutritional status of newly diagnosed ...
  • Neuromuscular disease genetics in underrepresented populations : increasing data diversity 
    Wilson, Lindsay A.; Macken, William L.; Perry, Luke D.; Record, Christopher J.; Schon, Katherine R.; Frezatti, Rodrigo S.S.; Raga, Sharika; Naidu, Kireshnee; Köken, Ozlem Yayıcı; Kapapa, Musambo M.; Dominik, Natalia; Efthymiou, Stephanie; Morsy, Heba; Nel, Melissa; Fassad, Mahmoud R.; Gao, Fei; Patel, Krutik; Schoonen, Maryke; Bisschoff, Michelle; Vorster, Armand; Jonvik, Hallgeir; Human, Ronel; Lubbe, Elsabeth (Elsa); Nonyane, Malebo; Vengalil, Seena; Nashi, Saraswati; Srivastava, Kosha; Lemmers, Richard J.L.F.; Reyaz, Alisha; Mishra, Rinkle; Topf, Ana; Trainor, Christina I.; Steyn, Elizabeth C.; Mahungu, Amokelani C.; Van der Vliet, Patrick J.; Ceylan, Ahmet Cevdet; Hiz, A. Semra; Cavdarlı, Bussranur; Gunduz, C. Nur Semerci; Ceylan, Gulay Gulec; Nagappa, Madhu; Tallapaka, Karthik B.; Govindaraj, Periyasamy; Van der Maarel, Silvere M.; Narayanappa, Gayathri; Nandeesh, Bevinahalli N.; Somwe, Wa Somwe; Bearden, David R.; Kvalsund, Michelle P.; Ramdharry, Gita M.; Oktay, Yavuz; Yis, Uluc; Topaloglu, Haluk; Sarkozy, Anna; Bugiardini, Enrico; Henning, Franclo; Wilmshurst, Jo M.; Heckmann, Jeannine M.; McFarland, Robert; Taylor, Robert W.; Smuts, Izelle; Van der Westhuizen, Francois H.; Da Rosa Sobreira, Claudia Ferreira; Tomaselli, Pedro J.; Marques Jr, Wilson; Bhatia, Rohit; Dalal, Ashwin; Srivastava, M.V. Padma; Yareeda, Sireesha; Nalini, Atchayaram; Vishnu, Venugopalan Y.; Thangaraj, Kumarasamy; Straub, Volker; Horvath, Rita; Chinnery, Patrick F.; Pitceathly, Robert D.S.; Muntoni, Francesco; Houlden, Henry; Vandrovcova, Jana; Reilly, Mary M.; Hanna, Michael G. (Oxford University Press, 2023-07)
    Neuromuscular diseases (NMDs) affect ∼15 million people globally. In high income settings DNA-based diagnosis has transformed care pathways and led to gene-specific therapies. However, most affected families are in ...
  • UNITY : a low-field magnetic resonance neuroimaging initiative to characterize neurodevelopment in low and middle-income settings 
    Abate, F.; Adu-Amankwah, A.; Ae-Ngibise, K.A.; Agbokey, F.; Agyemang, V.A.; Agyemang, C.T.; Akgun, C.; Ametepe, J.; Arichi, T.; Asante, K.P.; Balaji, S.; Baljer, L.; Basser, P.J.; Beauchemin, J.; Bennallick, C.; Berhane, Y.; Boateng-Mensah, Y.; Bourke, N.J.; Bradford, L.; Bruchhage, M.M.K.; Cano Lorente, R.; Cawley, P.; Cercignani, M.; D Sa, V.; De Canha, A.; Navarro, N.D.; Dean, D.C., III; Delarosa, J.; Donald, K.A.; Dvorak, A.; Edwards, A.D.; Field, D.; Frail, H.; Freeman, B.; George, T.; Gholam, J.; Guerrero-Gonzalez, J.; Hajnal, J.V.; Haque, R.; Hollander, W.; Hoodbhoy, Z.; Huentelman, M.; Jafri, S.K.; Jones, D.K.; Joubert, Fourie; Karaulanov, T.; Kasaro, M.P.; Knackstedt, S.; Kolind, S.; Koshy, B.; Kravitz, R.; Lafayette, S.L.; Lee, A.C.; Lena, B.; Lepore, N.; Linguraru, M.; Ljungberg, E.; Lockhat, Zarina I.; Loth, E.; Mannam, P.; Masemola, K.M.; Moran, R.; Murphy, D.; Nakwa, F.L.; Nankabirwa, V.; Nelson, C.A.; North, K.; Nyame, S.; O Halloran, R.; O'Muircheartaigh, J.; Oakley, B.F.; Odendaal, H.; Ongeti, C.M.; Onyango, D.; Oppong, S.A.; Padormo, F.; Parvez, D.; Paus, T.; Pepper, Michael Sean; Phiri, K.S.; Poorman, M.; Ringshaw, J.E.; Rogers, J.; Rutherford, M.; Sabir, H.; Sacolick, L.; Seal, M.; Sekoli, M.L.; Shama, T.; Siddiqui, K.; Sindano, N.; Spelke, M.B.; Springer, P.E.; Suleman, Farhana Ebrahim; Sundgren, P.C.; Teixeira, R.; Terekegn, W.; Traughber, M.; Tuuli, M.G.; Van Rensburg, Jeanne; Váša, F.; Velaphi, S.; Velasco, P.; Viljoen, I.M.; Vokhiwa, M.; Webb, A.; Weiant, C.; Wiley, N.; Wintermark, P.; Yibetal, K.; Deoni, S.C.L.; Williams, S.C.R. (Elsevier, 2024-10)
    Measures of physical growth, such as weight and height have long been the predominant outcomes for monitoring child health and evaluating interventional outcomes in public health studies, including those that may impact ...