BACKGROUND : In low- and middle-income countries (LMICs) such as South Africa, there is paucity of data on SARS-CoV-2
infections among children attending school, including seroprevalence and transmission dynamics.
OBJECTIVE ...
The Sisonke 2 study provided a homologous boost at least 6 months after administration of the priming dose of Ad26.COV2.S for healthcare workers enrolled on the Sisonke phase 3b implementation study.
Safety monitoring was ...
Geel, Jennifer A.; Hramyka, Artsiom; Du Plessis, Jan; Goga, Yasmin; Van Zyl, Anel; Hendricks, Marc G.; Naidoo, Thanushree; Mathew, Rema; Louw, Lizette; Neethling, Beverley; Schickerling, Tanya M.; Omar, Fareed E.; Du Plessis, Liezl; Madzhia, Elelwani; Netshituni, Vhutshilo; Eyal, Katherine; Ngcana, Thandeka V.Z.; Kelsey, Tom; Ballott, Daynia E.; Metzger, Monika L.(American Society of Clinical Oncology, 2024-10-24)
PURPOSE : Response assessment of classical Hodgkin lymphoma (cHL) with positron
emission tomography-computerized tomography (PET-CT) is standard of care
in well-resourced settings but unavailable in most African countries. ...
INTRODUCTION : Uganda has high maternal, neonatal, and under-five mortality rates. Between 2019 and 2021, the United Nations Children’s Fund (UNICEF), in collaboration with the Ministry of Health and other partners, ...
Airborne transmission of SARS-CoV-2 aerosol remains contentious. Importantly,
whether cough or breath-generated bioaerosols can harbor viable and
replicating virus remains largely unclarified. We performed size-fractio ...
Van Niekerk, Andre(Allergy Society of South Africa, 2024-03)
It was around 1973. Two years after the birth of David Vetter. David’s story captivated the mainstream media and the hearts of those who followed his sad case. He suffered from severe combined immunodeficiency (SCID) and his ...
Teixeira, Miguel Jose; Nagel, Lizelle; Van den Berg, Sylvia(Allergy Society of South Africa, 2024-09)
I am seeing a 25-year-old female patient who has a history of frequent respiratory infections since adolescence. She had an uneventful childhood, but started getting infections of increasing frequency and severity during ...
Brauer, Marieke; Nagel, Lizelle; Van den Berg, Sylvia(Allergy Society of South Africa, 2024-12)
HSV - can it be a clue to an underlying inborn error of immunity? I was recently contacted by a wife, concerned about her previously healthy 54-year-old husband, who suddenly complained of a severe headache. She noticed ...
Juggernath, Pearline; Mopeli, Keketso; Masekela, Refiloe; Dangor, Ziyaad; Goga, Ameena Ebrahim; Gray, Diane M.; Verwey, Charl(South African Medical Association, 2024-12)
BACKGROUND: Bronchiectasis, a chronic suppurative lung condition, is a largely neglected disease, especially in low- to middle-income
countries (LMICs), from which there is a paucity of data. Post-infectious causes are ...
In 2019 the National Department of Health (NDoH) conducted a national immunisation coverage survey of caregivers of children aged 24–35 months in all 52 districts of South Africa, and reported a national fully immunised ...
BACKGROUND : Surveillance systems for monitoring and reporting adverse events following immunisation (AEFI) and adverse events of special interest (AESI) are vital in understanding safety profiles of post-marketed vaccines. ...
Factors affecting the growth of HIV‐exposed‐uninfected (HEU) children are
multi‐factorial, with limited information available on the dietary intake from
6 months. This study compared the dietary intake, micronutrient ...
Smuts, Izelle; Human, Freda P.(Allergy Society of South Africa, 2024-03)
Inborn errors of immunity has become a rapidly evolving medical field, with nearly 500 conditions; as a result, the sheer
volume of information can be overwhelming. In order to make a sound diagnosis, clinicians must adopt ...
BACKGROUND : Preterm infants often have poor short- and long-term growth. Kangaroo
mother care supports short-term growth, but longer-term outcomes are unclear.
METHODS : This study analysed longitudinally collected ...
BACKGROUND :
Neonatal encephalopathy (NE) due to suspected hypoxic-ischemic encephalopathy (HIE), referred to as NESHIE, is a clinical diagnosis in late preterm and term newborns. It occurs as a result of impaired ...
Christie, Michael; Du Plessis, Nicolette Marie(AOSIS, 2024-03-30)
BACKGROUND : Birth HIV point-of-care (POC) tests curtail analytical testing issues and expedite diagnosis, potentially allowing for earlier mother-infant pair engagement and improved outcomes. Many children are lost post ...
BACKGROUND : The coronavirus disease 2019 (COVID-19) pandemic disrupted paediatric HIV
services across South Africa. Shortly before COVID-19, updated national HIV guidelines were
released.
OBJECTIVES : This study describes ...
Teixeira, Miguel Jose; Nagel, Lizelle; Plekker, Dante; Van der Merwe, Cassandre; Van den Berg, Sylvia(Allergy Society of South Africa, 2024-09-01)
Beryllium is used widely in industry due to its favourable elemental properties. Its extraction and subsequent incorporation
into alloys and composites generate hazardous fumes and dust. Chronic beryllium disease (CBD) ...
BACKGROUND : Globally, there is a significant gap in detailed neurodevelopmental data for infants under 3 months, despite 6 weeks being identified a critical milestone for neuro-behavioural development. Normative values ...