Nuclear Medicine: Recent submissions

Now showing items 21-40 of 202

Advances in radioligand theranostics in oncology

Lawal, Ismaheel Opeyemi; Abubakar, Sofiullah O.; Ndlovu, Honest; Mokoala, Kgomotso M.G.; More, Stuart; Sathekge, Mike Machaba (Springer, 2024-05)

Please read abstract in the article.
Second generation Al18F-labeled D-amino acid peptide for CXCR4 targeted molecular imaging

Spahn, Muriel Aline; Luyten, Kaat; Van Loy, Tom; Sathekge, Mike Machaba; Deroose, Christophe M.; Koole, Michel; Schols, Dominique; Vanduffel, Wim; De Vos, Kristof; Annaert, Pieter; Bormans, Guy; Cleeren, Frederik (Elsevier, 2024-05)

Please read abstract in the article.
225Ac-PSMA-617 radioligand therapy of de novo metastatic hormone-sensitive prostate carcinoma (mHSPC): preliminary clinical findings

Sathekge, Mike Machaba; Bruchertseifer, Frank; Vorster, Mariza; Lawal, Ismaheel Opeyemi; Mokoala, Kgomotso M.G.; Reed, Janet D.; Maserumule, Letjie; Ndlovu, Honest; Hlongwa, Khanyi; Maes, Alex; Morgenstern, Alfred; Van de Wiele, Christophe (Springer, 2023-06)

PURPOSE : 225Ac-PSMA-617 has demonstrated good anti-tumor effect as a treatment option for metastatic castration-resistant prostate cancer (mCRPC) patients. No study has previously assessed treatment outcome and survival ...
European Association of Nuclear Medicine Focus 5 : consensus on molecular imaging and theranostics in prostate cancer

Oprea-Lager, Daniela-Elena; MacLennan, Steven; Bjartell, Anders; Briganti, Alberto; Burger, Irene A.; De Jong, Igle; De Santis, Maria; Eberlein, Uta; Emmett, Louise; Fizazi, Karim; Gillessen, Silke; Herrmann, Ken; Heskamp, Sandra; Iagaru, Andrei; Jereczek-Fossa, Barbara Alicja; Kunikowska, Jolanta; Lam, Marnix; Nanni, Cristina; O’Sullivan, Joe M.; Panebianco, Valeria; Sala, Evis; Sathekge, Mike; Sosnowski, Roman; Tilki, Derya; Tombal, Bertrand; Treglia, Giorgio; Tunariu, Nina; Walz, Jochen; Yakar, Derya; Dierckx, Rudi; Sartor, Oliver; Fanti, Stefano (Elsevier, 2024-01)

BACKGROUND : In prostate cancer (PCa), questions remain on indications for prostatespecific membrane antigen (PSMA) positron emission tomography (PET) imaging and PSMA radioligand therapy, integration of advanced imaging ...
Principal component analysis applied to radiomics data : added value for separating benign from malignant solitary pulmonary nodules

Bomhals, Birte; Cossement, Lara; Maes, Alex; Sathekge, Mike Machaba; Mokoala, Kgomotso M.G.; Sathekge, Chabi; Ghysen, Katrien; Van de Wiele, Christophe (MDPI, 2023-12)

Please read abstract in article.
Tachykinin receptor-selectivity of the potential glioblastoma-targeted therapy, DOTA-[Thi8,Met(O2)11]-substance P

Suthiram, Janine; Pieters, Ane; Moosa, Zulfiah Mohamed; Zeevaart, Jan Rijn; Sathekge, Mike Machaba; Ebenhan, Thomas; Anderson, Ross Calley; Newton, Claire L. (MDPI, 2023-01)

Please read abstract in article.
89Zr-Leukocyte labelling for cell trafficking : in vitro and preclinical investigations

Kahts, Maryke; Guo, Hua; Kommidi, Harikrishna; Yang, Yanping; Sayman, Haluk Burcak; Summers, Beverley; Ting, Richard; Zeevaart, Jan Rijn; Sathekge, Mike Machaba; Aras, Omer (SpringerOpen, 2023-11-06)

BACKGROUND : The non-invasive imaging of leukocyte trafficking to assess inflammatory areas and monitor immunotherapy is currently generating great interest. There is a need to develop more robust cell labelling and ...
Quantitative chest X-ray radiomics for therapy response monitoring in patients with pulmonary tuberculosis

Du Plessis, Tamarisk; Rae, William Ian Duncombe; Ramkilawon, Gopika; Ramkilawon, Gopika Devi; Martinson, Neil Alexander; Sathekge, Mike Machaba (MDPI, 2023-09-01)

Tuberculosis (TB) remains the second leading cause of death globally from a single infectious agent, and there is a critical need to develop improved imaging biomarkers and aid rapid assessments of responses to therapy. ...
Detection of neutralizing antibodies in COVID-19 patients from Steve Biko Academic Hospital Complex : a pilot study

Kgatle, Mankgopo; Chalwe, Joseph Musonda; Van der Westhuizen, Donald; Xu, Shuting; Damane, Botle Precious; Mathebela, Precious; Ueckermann, Veronica; Mayaphi, Simnikiwe; Rodrigues, Hosana Gomes; Moura-Alves, Pedro; Ndlovu, Honest; Mzizi, Yonwaba; Zongo, Lusanda; Hairwadzi, Henry; Vorster, Mariza; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (MDPI, 2023-07-03)

A correlation between neutralization activity after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and protection against coronavirus disease 2019 (COVID-19) has been demonstrated by several ...
The theranostic optimization of PSMA-GCK01 does not compromise the imaging characteristics of [99mTc]Tc-PSMA-GCK01 compared to dedicated diagnostic [99mTc]Tc-EDDA/HYNIC-iPSMA in prostate cancer

Mamlins, Eduards; Scharbert, Lara; Cardinale, Jens; Krotov, Maria; Winter, Erik; Rathke, Hendrik; Strodel, Birgit; Ankrah, Alfred O; Sathekge, Mike Machaba; Haberkorn, Uwe; Kratochwil, Clemens; Giesel, Frederik L. (Springer, 2024-02)

Please read abstract in the article.
Update on PET radiopharmaceuticals for imaging hepatocellular carcinoma

Nyakale, Nozipho E.; Filippi, Luca; Aldous, Colleen; Sathekge, Mike Machaba (MDPI, 2023-04)

Numerous positron emission tomography (PET) targets for detection and staging of hepatocellular cancer have been developed in recent years. Hepatocellular carcinomas (HCCs) are clinically and pathologically heterogeneous ...
Correlation between [68Ga]Ga-FAPI-46 PET imaging and HIF-1 immunohistochemical analysis in cervical cancer: proof-of-concept

Mokoala, Kgomotso M.G.; Lawal, Ismaheel Opeyemi; Maserumule, Letjie C.; Bida, Meshack; Maes, Alex; Ndlovu, Honest; Reed, Janet D.; Mahapane, Johncy; Davis, Cindy; Van de Wiele, Christophe; Popoola, Gbenga; Giesel, Frederik L.; Vorster, Mariza; Sathekge, Mike Machaba (MDPI, 2023-08-03)

Hypoxia leads to changes in tumor microenvironment (upregulated CAFs) with resultant aggressiveness. A key factor in the physiological response to hypoxia is hypoxia-inducible factor-1alpha (HIF-1 ). [68Ga]Ga-FAPI PET ...
Spotlight : the status of radiopharmacy in Africa

Kleynhans, Janke; Summers, Beverly; Sakr, Tamer; Zeevaart, Jan Rijn; Lundie, Maryke; Du Plessis, Samantha; Mosima, Lerato; Bentaleb, Naoual; Ekoume, Fany P.; Hlongwa, Khanyisile N.; Shambel, Seble; Mldophane, Amanda; Mangatha, Amreeta; More, Stuart (Springer, 2024-04)

No abstract available.
Feasibility and acceptability of web-based structured oral examinations for postgraduate certification : mixed methods preliminary evaluation

Burch, Vanessa; McGuire, Jessica; Buch, Eric; Sathekge, Mike Machaba; M'bouaffou, Francis; Senkubuge, Flavia; Fagan, Johannes (JMIR Publications, 2024-03)

BACKGROUND : The COVID-19 pandemic disrupted postgraduate certification examinations globally. The Colleges of Medicine of South Africa continued hosting certification examinations through the pandemic. This was achieved ...
Barriers and enablers for implementation of digital-linked diagnostics models at point-of-care in South Africa : stakeholder engagement

Moetlhoa, Boitumelo; Nxele, Siphesihle Robin; Maluleke, Kuhlula; Mathebula, Evans Mantiri; Marange, Musa; Chilufya, Maureen; Dzinamarira, Tafadzwa; Duah, Evans; Dzobo, Matthias; Kekana, Mable; Jaya, Ziningi Nobuhle; Thabane, Lehana; Dlangalala, Thobeka Nomzamo; Nyasulu, Peter S.; Hlongwana, Khumbulani;; Dlungwane, Thembelihle; Kgatle, Mankgopo; Gxekea, Nobuhle; Mashamba‑Thompson, Tivani Phosa (BMC, 2024-02)

The integration of digital technologies holds significant promise in enhancing accessibility to disease diagnosis and treatment at point-of-care (POC) settings. Effective implementation of such interventions necessitates ...
Preclinical research highlighting contemporary targeting mechanisms of radiolabelled compounds for PET based infection imaging

Kleynhans, Janke; Sathekge, Mike Machaba; Ebenhan, Thomas (Elsevier, 2023-09)

It is important to constantly monitor developments in the preclinical imaging arena of infection. Firstly, novel radiopharmaceuticals with the correct characteristics must be identified to funnel into the clinic. Secondly, ...
Insights into peptidoglycan-targeting radiotracers for imaging bacterial infections : updates, challenges, and future perspectives

Koatale, Palesa Caroline; Welling, Mick M.; Ndlovu, Honest; Kgatle, Mankgopo; Mdanda, Sipho; Mdlophane, Amanda; Okem, Ambrose; Takyi-Williams, John; Sathekge, Mike Machaba; Ebenhan, Thomas (American Chemical Society, 2024-02)

The unique structural architecture of the peptidoglycan allows for the stratification of bacteria as either Gram-negative or Gram-positive, which makes bacterial cells distinguishable from mammalian cells. This classification ...
A decade of ubiquicidin development for PET imaging of infection : a systematic review

Marjanovic-Painter, Biljana; Kleynhans, Janke; Zeevaart, Jan Rijn; Rohwer, Egmont Richard; Ebenhan, Thomas (Elsevier, 2023-01)

BACKGROUND : Ubiquicidin is a peptide fragment with selective binding to negatively charged bacterial cell membranes. Besides its earlier labelling with gamma emitting radionuclides, it has been labelled with Positron ...
Prostate cancer skeletal metastasis: a spontaneous evolution from osteolytic to osteoblastic morphology without treatment

Lawal, Ismaheel Opeyemi; Bilen, Mehmet A.; Halkar, Raghuveer K.; Jani, Ashesh B.; Schuster, David M. (Thieme Gruppe, 2023-12)

Please read abstract in the article.
Quantification of pulmonary tuberculosis characteristics from digital chest x-rays using radiomics

Du Plessis, Tamarisk (University of Pretoria, 2023)

Pulmonary tuberculosis (PTB) is internationally one of the leading causes of death from a single infectious agent, and South Africa remains in the top 8 countries globally with the highest number of new infections. A chest ...

Now showing items 21-40 of 202

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