Recently added

Research Articles (Obstetrics and Gynaecology): Recent submissions

  • Consensus statement on the potential implementation of the sFlt-1/PlGF ratio in women with suspected pre-eclampsia 
    Matjila, M.; Anthony, J.; Vatish, M.; Moodley, J.; Bhorat, Ismail; Nicolaou, E.; Soma-Pillay, Priya; Monokoane, S.; Lombaard, H.; Chauke, L.; Pillay, T.; Mokaba, E. (Health and Medical Publishing Group, 2018-11)
    Pre-eclampsia is one of the leading causes of maternal and perinatal mortality and morbidity worldwide, and places a significant burden on the South African (SA) healthcare system. The soluble fms-like tyrosince kinase ...
  • Is pelvic floor morphology a predictor of successful pessary retention? Original research and review of the literature 
    Paterson, Frances; Abdool, Zeelha (Health and Medical Publishing Group, 2018)
    BACKGROUND : Vaginal pessaries are known to be an effective treatment modality for pelvic organ prolapse (POP). Pessaries form an important part of the physician’s armamentarium in the treatment of POP, but currently ...
  • Odon device for instrumental vaginal deliveries : results of a medical device pilot clinical study 
    Schvartzman, Javier A.; Krupitzki, Hugo; Merialdi, Mario; Betran, Ana Pilar; Requejo, Jennifer; Nguyen, My Huong; Vayena, Effy; Fiorillo, Angel E.; Gadow, Enrique C.; Vizcaino, Francisco M.; Von Petery, Felicitas; Marroquin, Victoria; Cafferata, María Luisa; Mazzoni, Agustina; Vannevel, Valerie; Pattinson, Robert Clive; Gulmezoglu, A. Metin; Althabe, Fernando; Bonet, Mercedes; World Health Organization Odon Device Research Group (BioMed Central, 2018-03-12)
    BACKGROUND : A prolonged and complicated second stage of labour is associated with serious perinatal complications. The Odon device is an innovation intended to perform instrumental vaginal delivery presently under development. ...
  • Reducing maternal deaths by skills-and-drills training in managing obstetric emergencies : a before-and-after observational study 
    Pattinson, Robert Clive; Bergh, Anne-Marie; Ameh, C.; Makin, J.A.; Pillay, Y.; Van den Broek, N.; Moodley, J. (Health and Medical Publishing Group, 2019-04)
    BACKGROUND. The institutional maternal mortality ratio (iMMR) in South Africa (SA) is still unacceptably high. A key recommendation from the National Committee on Confidential Enquiries into Maternal Deaths has been to ...
  • Assessment and management of venous thromboembolism risk during pregnancy and the puerperium (SAVE) : the South African cohort 
    Naidoo, Poobalan; Mothilal, R.; Snyman, Leon Cornelius (Health and Medical Publishing Group, 2019-03)
    BACKGROUND : Venous thromboembolism (VTE) is associated with significant morbidity and mortality. Pregnancy and the puerperium are hypercoagulable states and increase the risk of VTE. There is a paucity of South African ...
  • Approach to female urinary incontinence : Part 1 : Medical management 
    Paterson, Frances; Swart, Paul; Abdool, Zeelha (In House Publications, 2019)
    Urinary incontinence is defined as the involuntary loss of urine. It is a ubiquitous disorder, thought to occur more commonly than more familiar health issues such as hypertension, diabetes, and depression. It is a ...
  • Addressing the litigation crisis in Obstetrics & Gynaecology 
    Snyman, Leon Cornelius (In House Publications, 2019)
    Obstetricians & Gynaecologists in South Africa currently face a medico-legal crisis of serious proportions. The premiums of occurrence based indemnity insurance is now more than R1 million per annum, forcing many obstetricians ...
  • Association between gestational diabetes and biomarkers : a role in diagnosis 
    Adam, Sumaiya; Pheiffer, Carmen; Dias, Stephanie Charmaine; Rheeder, Paul (Taylor and Francis, 2018)
    BACKGROUND : We investigated the association between markers of insulin resistance, chronic inflammation, and adipokines and GDM. METHODS : In our case-cohort study in Johannesburg we included women with GDM and controls. ...
  • Making stillbirths visible : a systematic review of globally reported causes of stillbirth 
    Reinebrant, H.E.; Leisher, S.H.; Coory, M.; Henry, S.; Wojcieszek, A.M.; Gardener, G.; Lourie, R.; Ellwood, D.; Teoh, Z.; Allanson, E.; Blencowe, H.; Draper, E.S.; Erwich, J.J.; Frøen, J.F.; Gardosi, J.; Gold, K.; Gordijn, S.; Gordon, A.; Heazell, A.E.P.; Khong, T.Y.; Korteweg, F.; Lawn, J.E.; McClure, E.M.; Oats, J.; Pattinson, Robert Clive; Pettersson, K.; Siassakos, D.; Silver, R.M.; Smith, G.C.S.; Tunçalp, Ö.; Flenady, V. (Wiley, 2018-01)
    BACKGROUND : Stillbirth is a global health problem. The World Health Organization (WHO) application of the International Classification of Diseases for perinatal mortality (ICD‐PM) aims to improve data on stillbirth to ...
  • Use of a visual aid to improve estimation of blood loss in obstetrics 
    Makhubo, N.; Makin, J.D. (Jennifer Dianne); Adam, Sumaiya (Health and Medical Publishing Group, 2018-05)
    BACKGROUND. Postpartum haemorrhage (PPH) remains one of the most significant causes of maternal morbidity and mortality. In South Africa (SA) it is the second leading cause of maternal death. Educational programmes, such ...
  • Ovarian cysts and tumours in children and adolescents 
    Bryant, Emma P. (In House Publications, 2018)
    Ovarian masses are an uncommon finding in children and adolescents with an incidence of around 2.6/100000 per year excluding functional ovarian lesions of which the true incidence is unknown.1,2 While ovarian tumours ...
  • Starvation ketoacidosis in pregnancy presenting as euglycaemic-high anion gap metabolic acidosis : a case report highlighting the significance of early recognition and prompt intervention 
    Chausse, J.M.; Paruk, Fathima; Motilall, S.; Soma-Pillay, Priya; Ndaba, S. (Health and Medical Publishing Group, 2018-08)
    Starvation ketoacidosis (SKA) constitutes an important consideration in the pregnant patient who presents with profound metabolic acidosis. Pregnancy-related changes predispose the patient to develop SKA following relatively ...
  • Detection of hypermethylated genes as markers for cervical screening in women living with HIV 
    Kremer, Wieke W.; Van Zummeren, Marjolein; Novianti, Putri W.; Richter, Karin Louise; Verlaat, Wina; Snijders, Peter J.F.; Heideman, Danielle A.M.; Steenbergen, Renske D.M.; Dreyer, Greta; Meijer, Chris J.L.M. (Wiley Open Access, 2018-08)
    INTRODUCTION : To evaluate the performance of hypermethylation analysis of ASCL1, LHX8 and ST6GALNAC5 in physician-taken cervical scrapes for detection of cervical cancer and cervical intraepithelial neoplasia (CIN) grade ...
  • HPV16-related cervical cancers and precancers have increased levels of host cell DNA methylation in women living with HIV 
    Kremer, Wieke W.; Van Zummeren, Marjolein; Heideman, Daniëlle A.M.; Lissenberg-Witte, Birgit I.; Snijders, Peter J.F.; Steenbergen, Renske D.M.; Dreyer, Greta; Meijer, Chris J.L.M. (MDPI Publishing, 2018-10-23)
    Data on human papillomavirus (HPV) type-specific cervical cancer risk in women living with human immunodeficiency virus (WLHIV) are needed to understand HPV–HIV interaction and to inform prevention programs for this ...
  • Too little, too late : the recurrent theme in maternal deaths due to sepsis 
    Cebekhulu, Sylvia; Cornelissen, Laura; Pattinson, Robert Clive (In House Publications, 2018)
    BACKGROUND : Maternal sepsis accounts for 11% of direct obstetric deaths, making it the third commonest cause of death, after obstetric hemorrhage and hypertensive disorders. OBJECTIVE : To evaluate the risk factors and ...
  • Organophosphate poisoning in pregnancy : is it a cry for help? 
    Cebakulu, Sylvia; Pattinson, Robert Clive (Health and Medical Publishing Group, 2018-11)
    Organophosphate poisoning seems to be a fairly common cause of mortality in young and teenage mothers. The attending healthcare personnel, especially nursing staff and doctors, should always have a high index of suspicion ...
  • Systems thinking : a turning point for improving respectful obstetric care in South African health districts 
    Oosthuizen, Sarie J.; Bergh, Anne-Marie; Pattinson, Robert Clive (Health and Medical Publishing Group, 2018-11)
    Poorly functioning health systems and local health systems barriers affect many women giving birth in low- and middle-income countries. The district clinical specialist teams in South Africa are uniquely positioned to ...
  • Molecular biomarkers for gestational diabetes mellitus 
    Dias, Stephanie Charmaine; Pheiffer, Carmen; Abrahams, Yoonus; Rheeder, Paul; Adam, Sumaiya (MDPI Publishing, 2018-09-26)
    Gestational diabetes mellitus (GDM) is a growing public health problem worldwide. The condition is associated with perinatal complications and an increased risk for future metabolic disease in both mothers and their ...
  • Haemorrhage and other complications in pregnant women on anticoagulation for mechanical heart valves 
    Kariv, S.; Azibani, F.; Baard, J.; Osman, A.; Soma-Pillay, Priya; Anthony, J.; Sliwa, K. (Clinics Cardive, 2018-09)
    OBJECTIVE : To document maternal and foetal morbidity and mortality in anticoagulated, pregnant patients with mechanical heart valves until 42 days postpartum. METHODS : In a tertiary single-centre, prospective cohort, 178 ...
  • Cardiac disease in pregnancy : when to raise the ‘red flag’ 
    Soma-Pillay, Priya; Anthony, J.; Mandondo, S.D. (Health and Medical Publishing Group, 2018-11)
    Cardiac disease in pregnancy is an important cause of maternal morbidity and mortality and is the second most common cause of indirect maternal death in South Africa. Although most women with cardiac disease cope well ...