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Obstetrics and Gynaecology: Recent submissions

  • Protocol for developing a core outcome set for male infertility research : an international consensus development study 
    Rimmer, Michael P.; Howie, Ruth A.; Anderson, Richard A.; Barratt, Christopher L.R.; Barnhart, Kurt T.; Beebeejaun, Yusuf; Bertolla, Ricardo Pimenta; Bhattacharya, Siladitya; Bjorndahl, Lars; Bortoletto, Pietro; Brannigan, Robert E.; Cantineau, Astrid E.P.; Caroppo, Ettore; Collura, Barbara L.; Coward, Kevin; Eisenberg, Michael L.; De Geyter, Christian; Goulis, Dimitrios G.; Henkel, Ralf R.; Ho, Vu N.A.; Hussein, Alayman F.; Huyser, Carin; Kadijk, Jozef H.; Kamath, Mohan S.; Khashaba, Shadi; Kobori, Yoshitomo; Kopeika, Julia; Kucuk, Tansu; Lujan, Saturnino; Matsaseng, Thabo Christopher; Mathur, Raj S.; McEleny, Kevin; Mitchell, Rod T.; Mol, Ben W.; Murage, Alfred M.; Ng, Ernest H.Y.; Pacey, Allan; Perheentupa, Antti H.; Du Plessis, Stefan; Rives, Nathalie; Sarris, Ippokratis; Schlegel, Peter N.; Shabbir, Majid; Smiechowski, Maciej; Subramanian, Venkatesh; Sunkara, Sesh K.; Tarlarzis, Basil C.; Tuttelmann, Frank; Tuttelmann, Frank; Vail, Andy; Van Wely, Madelon; Vazquez-Levin, Monica H.; Vuong, Lan N.; Alex Y. Wang; Wang, Rui; Zini, Armand; Farquhar, Cindy M.; Niederberger, Craig; Duffy, James M.N. (Oxford University Press, 2022-03)
    STUDY QUESTION : We aim to develop, disseminate and implement a minimum data set, known as a core outcome set, for future male infertility research. WHAT IS KNOWN ALREADY : Research into male infertility can be challenging ...
  • Severe acute respiratory syndrome coronavirus 2 infection and pregnancy in Sub-Saharan Africa : a 6-country retrospective cohort analysis 
    Nachega, Jean B.; Sam-Agudu, Nadia A.; Machekano, Rhoderick N.; Rosenthal, Philip J.; Schell, Sonja; De Waard, Liesl; Bekker, Adrie; Gachuno, Onesmus W.; Kinuthia, John; Mwongeli, Nancy; Budhram, Samantha; Vannevel, Valerie; Soma-Pillay, Priya; Prozesky, Hans W.; Taljaard, Jantjie; Parker, Arifa; Agyare, Elizabeth; Opoku, Akwasi Baafuor; Makarfi, Aminatu Umar; Abdullahi, Asara M.; Adirieje, Chibueze; Ishoso, Daniel Katuashi; Pipo, Michel Tshiasuma; Tshilanda, Marc B.; Nswe, Christian Bongo-Pasi; Ditekemena, John; Sigwadhi, Lovemore Nyasha; Nyasulu, Peter S.; Hermans, Michel P.; Sekikubo, Musa; Musoke, Philippa; Nsereko, Christopher; Agbeno, Evans K.; Yeboah, Michael Yaw; Umar, Lawal W.; Ntakwinja, Mukanire; Mukwege, Denis M.; Birindwa, Etienne Kajibwami; Mushamuka, Serge Zigabe; Smith, Emily R.; Mills, Edward J.; Otshudiema, John Otokoye; Mbala-Kingebeni, Placide; Tamfum, Jean-Jacques Muyembe; Zumla, Alimuddin; Tsegaye, Aster; Mteta, Alfred; Sewankambo, Nelson K.; Suleman, Fatima; Adejumo, Prisca; Anderson, Jean R.; Noormahomed, Emilia V.; Deckelbaum, Richard J.; Stringer, Jeffrey S.A.; Mukalay, Abdon; Taha, Taha E.; Fowler, Mary Glenn; Wasserheit, Judith N.; Masekela, Refiloe; Mellors, John W.; Siedner, Mark J.; Myer, Landon; Kengne, Andre-Pascal; Yotebieng, Marcel; Mofenson, Lynne M.; Langenegger, Eduard; AFREhealth Research Collaboration on COVID-19 and Pregnancy (Oxford University Press, 2022-06-08)
    BACKGROUND : Few data are available on COVID-19 outcomes among pregnant women in sub-Saharan Africa (SSA), where high-risk comorbidities are prevalent. We investigated the impact of pregnancy on SARS-CoV-2 infection and ...
  • Superficial spreading cervical squamous cell carcinoma in situ with extensive endomyometrial infiltration masquerading as a primary endometrial cancer 
    Olivier, H.J.; Snyman, Leon Cornelius; Oliva, E.; Slavik, Tomas (MedPharm Publications, 2022-12)
    The presence of squamous cell carcinoma (SCC) on endometrial histology raises the possibility of a primary endometrial carcinoma, as well as secondary endometrial involvement by SCC from another site, especially the cervix. ...
  • Time- and glucose-dependent differentiation of 3T3-L1 adipocytes mimics dysfunctional adiposity 
    Jackson, Hayley C.; Pheiffer, Carmen; Jack, Babalwa; Africander, Donita (Elsevier, 2023-09)
    The 3T3-L1 murine adipocyte cell line remains one of the most widely used models to study the mechanisms of obesity and related pathologies. Most studies investigate such mechanisms using mature adipocytes that have been ...
  • Development of a screening algorithm for the cervical cancer prevention programme in Botswana 
    Ramogola-Masire, Doreen (University of Pretoria, 2023)
    In this thesis, Development of a screening algorithm for the cervical cancer prevention programme in Botswana, the candidate utilised a new human papillomavirus (HPV) deoxyribonucleic acid (DNA) assay called Antila AmpFire ...
  • The impact of climate change on maternal and child health 
    Soma-Pillay, Priya; Wium, L.; Pillay, Yogan (Netherlands Press, 2022-11)
    It can be argued that there are three colliding pandemics that are currently affecting the planet and its people: COVID-19, global inequities and climate change. Regrettably, these are all the result of human action or ...
  • Iron deficiency in women’s health : an understated burden with serious health consequences 
    Dreyer, Greta; Zondagh, Jake (Netherlands Press, 2022-01)
    The importance of iron for overall health in humans cannot be overstated and its extremely widespread biological functions include electron transfer, intercellular signalling, catalysis, and oxygen binding and transport. ...
  • Expressed informed consent for intimate gynaecological examinations 
    Snyman, Leon Cornelius (Netherlands Press, 2022-07)
    The doctor-patient relationship, although extremely important and essential to ensure optimal treatment outcomes, remains complicated. This relationship allows two people, unfamiliar with each other, with different value ...
  • Transverse vaginal septum in a young adolescent : a case report describing a novel approach in the initial surgical management 
    Mbambu, T.; Snyman, Leon Cornelius (Netherlands Press, 2022-01)
    Transverse vaginal septum is a rare congenital anomaly. It is one of the variants of müllerian duct anomalies which results from defective fusion or recanalization of the vaginal and müllerian organs. It can present with ...
  • Placental malaria : a threat to obstetric outcomes 
    Molokoane, Felicia; Seopela, Louisa; Sajo, Adekunle Emmanuel (Netherlands Press, 2022-01)
    Placental malaria occurs when there is sequestration of Plasmodium falciparum infected red blood cells in the placenta. This is the primary mechanism by which malaria in pregnancy perpetuates its adverse perinatal outcomes ...
  • Accessibility and acceptability of women receiving medical terminations of pregnancy at Kalafong Provincial Tertiary Hospital 
    Chigumadzi, Peter Farai; Lubega, Sheila Nansamba; Bryant, Emma P.; Snyman, Leon Cornelius (Netherlands Press, 2022-11)
    BACKGROUND : The South African Choice on Termination of Pregnancy Act was passed in 1996, legalizing a women’s right to request a termination of pregnancy. Despite this legislation, there are still a large number of women ...
  • A descriptive study of acute kidney injury in obstetric patients at Kalafong Provincial Tertiary Hospital 
    Nakanyane, T.E.; Molokoane, Felicia; Snyman, Leon Cornelius (The Netherlands Press, 2022-01)
    BACKGROUND : Acute kidney injury (AKI) in pregnancy presents with complexities relating to the pathophysiology of the disease. It is associated with an increased risk of maternal and perinatal morbidity and mortality. ...
  • The key role of examining the placenta in establishing a probable cause for stillbirth 
    Odendaal, Hein; Pattinson, Robert Clive; Schubert, Pawel; Mason, Deidre; Brink, Lucy; Gebhardt, Stefan; Groenewald, Coenraad; Wright, Colleen (Elsevier, 2022-11)
    INTRODUCTION : Autopsy is regarded as the “gold standard” to determine probable causes of stillbirths. However, autopsy is expensive and not readily available in low- and middle-income countries. Therefore, we assessed how ...
  • Early childhood growth parameters in South African children with exposure to maternal HIV infection and placental insufficiency 
    Nyofane, Mothusi; Hoffman, Marinel; Mulol, Helen; Botha, Tanita; Vannevel, Valerie; Pattinson, Robert Clive; Feucht, Ute Dagmar (MDPI, 2022-12-09)
    Maternal HIV exposure and intrauterine growth restriction (IUGR) due to placental insufficiency both carry major risks to early child growth. We compared the growth outcomes of children aged 18 months who had abnormal ...
  • Accurate anatomic repair of obstetric anal sphincter damage or rectovaginal fistula aided by prior ultrasonograghy : a cohort study 
    Mokoena, Taole; Abdool, Zeelha (Wolters Kluwer Health, 2023-06)
    BACKGROUND : Anorectal obstetric injuries resulting in anal sphincter damage (ASD) and rectovaginal fistula (RVF) remain a major problem. The resulting flatus or faecal incontinence is devastating. Surgical repair remains ...
  • Cotrimoxazole guidelines for infants who are HIV-exposed but uninfected : a call for a public health and ethics approach to the evidence 
    Daniels, Brodie; Kuhn, Louise; Spooner, Elizabeth; Mulol, Helen; Goga, Ameena Ebrahim; Feucht, Ute Dagmar; Essack, Sabiha Y.; Coutsoudis, Anna (Elsevier, 2022-08)
    WHO first recommended cotrimoxazole prophylaxis for all infants who are HIV-exposed but uninfected (HEU) in 2000, given the ability of this treatment to prevent mortality from pneumocystis pneumonia in adults living with ...
  • Decreased severity of disease during the first global Omicron variant COVID-19 outbreak in a large hospital in Tshwane, South Africa 
    Abdullah, Fareed; Myers, J.; Basu, Debashis; Tintinger, Gregory; Ueckermann, Veronica; Mathebula, M.; Ramlall, R.; Spoor, S.; De Villiers, T.; Van der Walt, Z.; Cloete, Jeane; Soma-Pillay, Priya; Rheeder, Paul; Paruk, Fathima; Engelbrecht, Adel; Lalloo, Vidya; Myburg, M.; Kistan, J.; Van Hougenhouck-Tulleken, Wesley G.; Boswell, Michael T.; Gray, G.; Welch, R.; Blumberg, Lucille Hellen; Jassat, W. (Elsevier, 2022-03)
    INTRODUCTION : The coronavirus disease 2019 (COVID-19) first reported in Wuhan, China in December 2019 is a global pandemic that is threatening the health and wellbeing of people worldwide. To date there have been more ...
  • Age-specific burden of cervical cancer associated with HIV : a global analysis with a focus on sub-Saharan Africa 
    Khalil, Ahmadaye Ibrahim; Mpunga, Tharcisse; Wei, Feixue; Baussano, Iacopo; De Martel, Catherine; Bray, Freddie; Stelzle, Dominik; Dryden-Peterson, Scott; Jaquet, Antoine; Horner, Marie-Josephe; Awolude, Olutosin A.; Trejo, Mario Jesus; Mudini, Washington; Soliman, Amr S.; Sengayi-Muchengeti, Mazvita; Coghill, Anna E.; Van Aardt, M.C. (Matthys Cornelis); De Vuyst, Hugo; Hawes, Stephen E.; Broutet, Nathalie; Dalal, Shona; Clifford, Gary M. (Wiley, 2022-03)
    HIV substantially worsens human papillomavirus (HPV) carcinogenicity and contributes to an important population excess of cervical cancer, particularly in sub- Saharan Africa (SSA). We estimated HIV- and age-stratified ...
  • The clinical application of transperineal ultrasound in urogynaecology 
    Retief, F.; Paterson, Frances; Jagiellowicz, J.; Swart, Paul; Abdool, Zeelha; Dietz, Hans Peter (Wiley, 2022-07)
    KEY CONTENT : Transperineal ultrasound allows reproducible imaging of pelvic floor conditions that aids in the thorough assessment required to diagnose and treat urogynaecological conditions. Views that can ...
  • Early reflections on Mphatlalatsane, a maternal and neonatal quality improvement initiative implemented during COVID-19 in South Africa 
    Odendaal, W.; Goga, Ameena Ebrahim; Chetty, Terusha; Schneider, Helen; Pillay, Yogan; Marshall, Carol; Feucht, Ute Dagmar; Hlongwane, T.M.A.G. (Tsakane); Kauchali, Shuaib; Makua, Manala (Johns Hopkins Center for Communication Programs, 2022-10-21)
    Despite global progress in reducing maternal and neonatal mortality and stillbirths, much work remains to be done to achieve the Sustainable Development Goals. Reports indicate that coronavirus disease (COVID-19) disrupts ...