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Obstetrics and Gynaecology: Recent submissions

  • Starvation ketoacidosis in pregnancy presenting as euglycaemic-high anion gap metabolic acidosis : a case report highlighting the significance of early recognition and prompt intervention 
    Chausse, J.M.; Paruk, Fathima; Motilall, S.; Soma-Pillay, Priya; Ndaba, S. (Health and Medical Publishing Group, 2018-08)
    Starvation ketoacidosis (SKA) constitutes an important consideration in the pregnant patient who presents with profound metabolic acidosis. Pregnancy-related changes predispose the patient to develop SKA following relatively ...
  • Detection of hypermethylated genes as markers for cervical screening in women living with HIV 
    Kremer, Wieke W.; Van Zummeren, Marjolein; Novianti, Putri W.; Richter, Karin Louise; Verlaat, Wina; Snijders, Peter J.F.; Heideman, Danielle A.M.; Steenbergen, Renske D.M.; Dreyer, Greta; Meijer, Chris J.L.M. (Wiley Open Access, 2018-08)
    INTRODUCTION : To evaluate the performance of hypermethylation analysis of ASCL1, LHX8 and ST6GALNAC5 in physician-taken cervical scrapes for detection of cervical cancer and cervical intraepithelial neoplasia (CIN) grade ...
  • HPV16-related cervical cancers and precancers have increased levels of host cell DNA methylation in women living with HIV 
    Kremer, Wieke W.; Van Zummeren, Marjolein; Heideman, Daniëlle A.M.; Lissenberg-Witte, Birgit I.; Snijders, Peter J.F.; Steenbergen, Renske D.M.; Dreyer, Greta; Meijer, Chris J.L.M. (MDPI Publishing, 2018-10-23)
    Data on human papillomavirus (HPV) type-specific cervical cancer risk in women living with human immunodeficiency virus (WLHIV) are needed to understand HPV–HIV interaction and to inform prevention programs for this ...
  • Too little, too late : the recurrent theme in maternal deaths due to sepsis 
    Cebekhulu, Sylvia; Cornelissen, Laura; Pattinson, Robert Clive (In House Publications, 2018)
    BACKGROUND : Maternal sepsis accounts for 11% of direct obstetric deaths, making it the third commonest cause of death, after obstetric hemorrhage and hypertensive disorders. OBJECTIVE : To evaluate the risk factors and ...
  • Organophosphate poisoning in pregnancy : is it a cry for help? 
    Cebakulu, Sylvia; Pattinson, Robert Clive (Health and Medical Publishing Group, 2018-11)
    Organophosphate poisoning seems to be a fairly common cause of mortality in young and teenage mothers. The attending healthcare personnel, especially nursing staff and doctors, should always have a high index of suspicion ...
  • Systems thinking : a turning point for improving respectful obstetric care in South African health districts 
    Oosthuizen, Sarie J.; Bergh, Anne-Marie; Pattinson, Robert Clive (Health and Medical Publishing Group, 2018-11)
    Poorly functioning health systems and local health systems barriers affect many women giving birth in low- and middle-income countries. The district clinical specialist teams in South Africa are uniquely positioned to ...
  • Molecular biomarkers for gestational diabetes mellitus 
    Dias, Stephanie Charmaine; Pheiffer, Carmen; Abrahams, Yoonus; Rheeder, Paul; Adam, Sumaiya (MDPI Publishing, 2018-09-26)
    Gestational diabetes mellitus (GDM) is a growing public health problem worldwide. The condition is associated with perinatal complications and an increased risk for future metabolic disease in both mothers and their ...
  • Haemorrhage and other complications in pregnant women on anticoagulation for mechanical heart valves 
    Kariv, S.; Azibani, F.; Baard, J.; Osman, A.; Soma-Pillay, Priya; Anthony, J.; Sliwa, K. (Clinics Cardive, 2018-09)
    OBJECTIVE : To document maternal and foetal morbidity and mortality in anticoagulated, pregnant patients with mechanical heart valves until 42 days postpartum. METHODS : In a tertiary single-centre, prospective cohort, 178 ...
  • Cardiac disease in pregnancy : when to raise the ‘red flag’ 
    Soma-Pillay, Priya; Anthony, J.; Mandondo, S.D. (Health and Medical Publishing Group, 2018-11)
    Cardiac disease in pregnancy is an important cause of maternal morbidity and mortality and is the second most common cause of indirect maternal death in South Africa. Although most women with cardiac disease cope well ...
  • Obstetrics knowledge and skills training as a catalyst for change 
    Pattinson, Robert Clive; Bergh, Anne-Marie; Makin, J.D. (Jennifer Dianne); Pillay, Y.; Moodley, J.; Madaj, B.; Ameh, C.; Van den Broek, N. (Health and Medical Publishing Group, 2018-09)
    BACKGROUND. Poor emergency obstetric care has been shown by national confidential enquiries into maternal deaths to contribute to a number of maternal deaths in South Africa. OBJECTIVES. To assess whether a structured ...
  • Changes to the World Health Organization guideline on hormonal contraceptive eligibility for women at high risk of HIV : South African perspective and response 
    Nene, Zozo; Hofmeyr, G.J.; Patel, M.; Panday, M.; Rees, H.; Makua, M.; Pillay, Yogan (Health and Medical Publishing Group, 2018-08)
    The World Health Organization (WHO) published guidelines for hormonal contraceptive eligibility for women at high risk of HIV in March 2017. This guidance followed from a technical consultative meeting convened by the WHO ...
  • Global perspectives on operative vaginal deliveries 
    Vannevel, Valerie; Swanepoel, C.; Pattinson, Robert Clive (Elsevier, 2019-04)
    Operative vaginal delivery (OVD) refers to the use of an instrument (forceps or vacuum device), to assist with delivery of the fetus from the vagina. This can help improve maternal and fetal outcomes and has to be weighed ...
  • Use of a sentinel lymph node biopsy algorithm in a South African population of patients with cervical cancer and high prevalence of human immunodeficiency virus infection 
    Snyman, Leon Cornelius; Bryant, Emma P.; Wethmar, E.I. (Elize); De Greve, Tom; Reyneke, Florette; Sathekge, Mike Machaba; Lindeque, B. Gerhard; Abu-Rustum, Nadeem R. (Lippincott Williams and Wilkins, 2018-09)
    OBJECTIVES : Cervical cancer is common in resource-poor settings with high prevalence of tuberculosis, pelvic inflammatory disease, and human immunodeficiency virus (HIV) infection. There are no data regarding the sentinel ...
  • NT-proBNP : when is it useful in obstetric medicine? 
    Ker, James A.; Soma-Pillay, Priya (Sage, 2018-03)
    Pregnancy, viewed as a stress test of the haemodynamic system, may unmask underlying cardiac disease. Pregnancy may also induce de novo cardiac disease. N-terminal pro brain-type natriuretic peptide (NT-proBNP) is a useful ...
  • Obesity, oligomenorrhoea and PCOS in adolescence 
    (In House Publications, 2018)
    Polycystic ovarian syndrome (PCOS) is the most common endocrinopathy affecting female reproductive health. The diagnosis of PCOS in adolescence is challenging due to the high prevalence of menstrual dysfunction and acne ...
  • Teenage pregnancy considerations 
    Molokoane, Felicia (In House Publications, 2018)
    Teen pregnancy has serious consequences for young women, their children and communities as a whole. Teenage pregnancy is defined as a teenage girl, usually within ages of 13 – 19, becoming pregnant. This refers to girls ...
  • Adolescents, contraception and termination of pregnancy 
    Rajoo, Neesha (In House Publications, 2018)
    The female adolescent patient has a variety of gynaecological issues which the healthcare practitioner needs to understand and pay particular attention to, ranging from screening for sexual health history, teenage ...
  • Adolescent heavy menstrual bleeding and dymenorrhoea 
    Maphalala, Alta (In House Publications, 2018)
    Menstrual disorders are common conditions in adolescents, with Heavy Menstrual Bleeding (HMB) having a prevalence of 37% in adolescents compared to 10-20% in adults, and dysmenorrhoea accounting for approximately 15% ...
  • Adolescent sexuality, STI’s and HPV 
    Naidoo, Anusha (In House Publications, 2018)
    Adolescence refers to the transitional phase of physical and psychological development that occurs from puberty to adulthood. This phase includes a desire for autonomy and an increase in sexual risk-taking behaviours, ...
  • The Child Act, consent matters and obstetrics and gynaecology 
    Adam, Sumaiya; Lindeque, B. Gerhard (In House Publications, 2018)
    This edition of the O&G Forum is dedicated to various aspects of Obstetrical and Gynaecological care of nadolescents. In modern medical ethics, patient autonomy is considered a major principle in decision-making regarding ...