• Gestation-dependent increase in cervicovaginal pro-inflammatory cytokines and cervical extracellular matrix proteins is associated with spontaneous preterm delivery within 2 weeks of index assessment in South African women 

  Amabebe, Emmanuel; Ikumi, Nadia; Oosthuizen, Ally; Soma-Pillay, Priya; Matjila, Mushi; Anumba, Dilly O. C. (Frontiers Media, 2024-08)

  INTRODUCTION: Inflammation-induced remodelling of gestational tissues that underpins spontaneous preterm birth (sPTB, delivery < 37 weeks’ gestation) may vary by race and context. To explore relationships between markers ...
• Assessment of current biomarkers and interventions to identify and treat women at risk of preterm birth 

  Gravett, Michael G.; Menon, Ramkumar; Tribe, Rachel M.; Hezelgrave, Natasha L.; Kacerovsky, Marian; Soma-Pillay, Priya; Jacobsson, Bo; McElrath, Thomas F. (Frontiers Media, 2024-07)

  Preterm birth remains an important global problem, and an important contributor to under-5 mortality. Reducing spontaneous preterm birth rates at the global level will require the early identification of patients at risk ...
• Comparative effects of tumor necrosis factor alpha, lipopolysaccharide, and palmitate on mitochondrial dysfunction in cultured 3T3-L1 adipocytes 

  Jack, Babalwa U.; Dias, Stephanie; Pheiffer, Carmen (Springer, 2024)

  We have previously reported that dysregulated lipid metabolism and inflammation in 3T3-L1 adipocytes is attributed to tumor necrosis factor alpha (TNFα) rather than lipopolysaccharide (LPS) and palmitate (PA). In this ...
• The need for diverting colostomy in obstetric and non-obstetric anorectal injury repair 

  Blignaut, Quinton Craig; Abdool, Zeelha (Inhouse Publishers, 2023-05)

  Between 0,2% and 6% of women experience severe anorectal injuries in the form of third- and fourth-degree tears during vaginal birth. Early diagnosis and correct repair by experienced surgeons reduce morbidity and devastating ...
• A design thinking approach to disentangle the wicked problem of re-curriculation during a pandemic 

  Lubbe, Johanna Catharina (Irene); Adam, Sumaiya; Cordier, Werner (Unisa Press, 2023-10)

  Covid-19 continues to cause major disruptions and unique challenges in the higher education sector. Some of the most profound disruptions are in health sciences where students depend on current, up-to-date information, ...
• The performance of single and combination test strategies using visual inspection, cytology, high-risk HPV DNA and HPV16/18 to screen South African women with and without HIV-infection 

  Dreyer, Greta; Visser, Cathy; Dreyer, Gerrit Jan; Botha, Matthys H.; Van der Merwe, Frederick H.; Richter, Karin Louise; Snyman, Leon Cornelius (BMC, 2024-05)

  BACKGROUND : Cervical cancer screening strategies should ideally be informed by population-specific data. Strategies recommended for secondary prevention, are often inadequately studied in populations with high cervical ...
• FIGO good practice recommendations on optimizing models of care for the prevention and mitigation of preterm birth 

  Anumba, Dilly; Soma-Pillay, Priya; Bianchi, Ana; Gonzalez, Catalina M. Valencia; Jacobbson, Bo; FIGO Committee for Preterm Birth (Wiley, 2024-09)

  The global challenge of preterm birth persists with little or no progress being made to reduce its prevalence or mitigate its consequences, especially in low-resource settings where health systems are less well developed. ...
• Management of obesity across women's life course : FIGO best practice advice 

  Maxwell, Cynthia V.; Shirley, Rachelle; O'Higgins, Amy C.; Rosser, Mary L.; O'Brien, Patrick; Hod, Moshe; O'Reilly, Sharleen L.; Medina, Virna P.; Smith, Graeme N.; Hanson, Mark A.; Adam, Sumaiya; Ma, Ronald C.; Kapur, Anil; McIntyre, Harold David; Jacobsson, Bo; Poon, Liona C.; Bergman, Lina; Regan, Lesley; Algurjia, Esraa; McAuliffe, Fionnuala M.; FIGO Committee on Impact of Pregnancy on Long-term Health and the FIGO Division of Maternal and Newborn Health (Wiley, 2023-01)

  Obesity is a chronic, progressive, relapsing, and treatable multifactorial, neurobehavioral disease. According to the World Health Organization, obesity affects 15% of women and has long-term effects on women's health. ...
• Evaluation of the medically necessary, time sensitive triage score during and beyond the local COVID-19 pandemic in the gynaecologic oncology unit of a tertiary hospital in South Africa 

  Sajo, Adekunle Emmanuel; Mouton, Arrie; Olorunfemi, Gbenga; Visser, Cathy; Van Aardt, M.C. (Matthys Cornelis); Dreyer, Greta (Public Library of Science, 2023-04-13)

  OBJECTIVE : The main objective of this study was to evaluate the Medically Necessary Time Sensitive (MeNTS) scoring system in triaging gynaecologic oncologic surgery during and beyond the COVID-19 pandemic. MATERIAL AND ...
• Accuracy of a smartphone application for blood pressure estimation in Bangladesh, South Africa, and Tanzania 

  Festo, Charles; Vannevel, Valerie; Ali, Hasmot; Tamrat, Tigest; Mollel, Getrud J.; Hlongwane, T.M.A.G. (Tsakane); Fahmida, Kaniz A.; Alland, Kelsey; Barreix, María; Mehrtash, Hedieh; Silva, Ronaldo; Thwin, Soe Soe; Mehl, Garrett; Labrique, Alain B.; Masanja, Honorati; Tuncalp, Ozge (Wiley, 2023-04-17)

  Undetected and unmonitored hypertension carries substantial mortality and morbidity, especially during pregnancy. We assessed the accuracy of OptiBPTM, a smartphone application for estimating blood pressure (BP), across ...
• Dietary supplements potentially target plasma glutathione levels to improve cardiometabolic health in patients with diabetes mellitus : a systematic review of randomized clinical trials 

  Dludla, Phiwayinkosi V.; Ziqubu, Khanyisani; Mabhida, Sihle E.; Mazibuko-Mbeje, Sithandiwe E.; Hanser, Sidney; Nkambule, Bongani B.; Basson, Albertus K.; Pheiffer, Carmen; Tiano, Luca; Kengne, Andre P. (MDPI, 2023-02-14)

  Cardiovascular diseases (CVDs) continue to be the leading cause of death in people with diabetes mellitus. Severely suppressed intracellular antioxidant defenses, including low plasma glutathione (GSH) levels, are ...
• Using FIGO nutrition checklist counselling in pregnancy : a review to support healthcare professionals 

  Killeen, Sarah Louise; Donnellan, Niamh; O'Reilly, Sharleen L.; Hanson, Mark A.; Rosser, Mary L.; Medina, Vina P.; Jacob, Chandni Maria; Divakar, Hema; Hod, Moshe; Poon, Liona C.; Bergman, Lina; O'Brien, Patrick; Kapur, Anil; Jacobsson, Bo; Maxwell, Cynthia V.; McIntyre, Harold David; Regan, Lesley; Algurjia, Esraa; Ma, Ronald C.; Adam, Sumaiya; FIGO Committee on Impact of Pregnancy on Long-term Health and the FIGO Division of Maternal and Newborn Health (Wiley, 2023-01)

  The period before and during pregnancy is increasingly recognized as an important stage for addressing malnutrition. This can help to reduce the risk of noncommunicable diseases in mothers and passage of risk to their ...
• Pregnancy as an opportunity to prevent type 2 diabetes mellitus : FIGO best practice advice 

  Adam, Sumaiya; McIntyre, Harold David; Tsoi, Kit Ying; Kapur, Anil; Ma, Ronald C.; Dias, Stephanie; Okong, Pius; Hod, Moshe; Poon, Liona C.; SmithGraeme N.; Smith, Graeme N.; Bergman, Lina; Algurjia, Esraa; O'Brien, Patrick; Medina, Vina P.; Maxwell, Cynthia V.; Regan, Lesley; Rosser, Mary L.; Jacobsson, Bo; Hanson, Mark A.; O'Reilly, Sharleen L.; FIGO Committee on the Impact of Pregnancy on Long-term Health and the FIGO Division of Maternal and Newborn Health (Wiley, 2023-01)

  Gestational diabetes (GDM) impacts approximately 17 million pregnancies worldwide. Women with a history of GDM have an 8–10- fold higher risk of developing type 2 diabetes and a 2-fold higher risk of developing ...
• Hypertensive disorders of pregnancy and long-term cardiovascular health : FIGO best practice advice 

  Poon, Liona C.; Nguyen-Hoang, Long; Smith, Graeme N.; Bergman, Lina; O'Brien, Patrick; Hod, Moshe; Okong, Pius; Kapur, Anil; Maxwell, Cynthia V.; McIntyre, Harold David; Jacobsson, Bo; Algurjia, Esraa; Hanson, Mark A.; Rosser, Mary L.; Ma, Ronald C.; O'Reilly, Sharleen L.; Regan, Lesley; Adam, Sumaiya; Medina, Virna P.; McAuliffe, Fionnuala M.; FIGO Committee on the Impact of Pregnancy on Long-term Health and the FIGO Division of Maternal and Newborn Health (Wiley, 2023-01)

  Hypertensive disorders of pregnancy (HDP) are the most common causes of maternal and perinatal morbidity and mortality. They are responsible for 16% of maternal deaths in high-income countries and approximately 25% in ...
• Pregnant women's dietary patterns and knowledge of gestational weight gain : a cross-sectional study 

  Dikgale, Busisiwe; Dlakavu, Fuziwe; Masenge, Andries; De Gouveia, Slava; Adam, Sumaiya (Wiley, 2024-08)

  OBJECTIVE : Excess gestational weight gain (GWG) is a risk factor for various unfavorable maternal and neonatal outcomes that may be preventable. Maintaining a healthy lifestyle while pregnant can help prevent uncontrollable ...
• Effective and simple interventions to improve outcomes for preterm infants worldwide : the FIGO PremPrep-5 initiative 

  Hall, Megan; Valencia, Catalina M.; Soma-Pillay, Priya; Luyt, Karen; Jacobsson, Bo; Shennan, Andrew (Wiley, 2024-06)

  Preterm birth remains the leading cause of mortality among under-5's and is a major contributor to the reduction in quality-of-life adjusted years and reduction in human capital. Globally, there are many interventions and ...
• Variations in pelvic floor thickness in relation to bony dimensions in South African women : using computed tomography scans 

  Kobedi, Ruth; Jagesur, Suvasha; Abdool, Zeelha; Oettle, Jacobus; Oettle, Anna C. (Spanish Association of Anatomy, 2024-07)

  Pelvic floor disorders (PFDs) are a common reason for urogynaecological consultation around the world, especially in elderly women. These disorders have been associated with disruption to the structural integrity of the ...
• Causation of term perinatal hypoxic-ischaemic basal ganglia and thalamus injury in the context of cerebral palsy litigation : position statement 

  Bhorat, Ismail; Buchmann, E.; Frank, K.; Soma-Pillay, Priya; Nicolaou, E.; Pistorius, L.; Smuts, Izelle (Health and Medical Publishing Group, 2023-09)

  Basal ganglia and thalamus (BGT) hypoxic-ischaemic brain injury is currently the most contentious issue in cerebral palsy (CP) litigation in South Africa (SA), and merits a consensus response based on the current available ...
• Visual inspection using naked eye and colposcopy as a predictor of high-grade lesions on final histology in HIV-positive and -negative South African women 

  Adams, Robyn A.; Dreyer, Greta; Snyman, Leon Cornelius; Visser, Cathy; Dreyer, G.J.; Breidenthal, Anne G.; Frenzel, C.; Van der Merwe, Frederick; Botha, Matthys H. (Medpharm Publications, 2023-06)

  BACKGROUND: Although potentially preventable, cervical cancer is the fourth most common cancer among women globally and a leading cause of cancer-related deaths. Women living in resource-limited countries are especially ...
• Simplicity sacrificed in the FIGO 2023 endometrial cancer staging : demystifying the complexity of twelve stages and seventeen substages 

  Dreyer, Greta; Snyman, Leon Cornelius (MedPharm Publications, 2023)

  Endometrial cancer incidence is rapidly rising globally, and in recent years, research has gained significant momentum. Surgical techniques, histopathology classification, risk stratification and understanding of different ...

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