Screening of the venoms of two Parabuthus scorpion species on isolated cardiomyocytes

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dc.contributor.author Van Aarde, M.N.
dc.contributor.author Van Rooyen, J.M.
dc.contributor.author Van Aswegen, G.
dc.contributor.editor Verwoerd, Daniel Wynand
dc.date.accessioned 2013-08-27T07:25:32Z
dc.date.available 2013-08-27T07:25:32Z
dc.date.created 2013
dc.date.issued 1996
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat X Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en
dc.description.abstract Crude, diluted venoms of Parabuthus transvaalicus and P. granulatus were tested on isolated cardiomyocytes. Ventricular myocytes were subjected to hypercontractility tests and whole-cell voltage clamp. Both venoms had a profound influence on the hypercontractility of cardiomyocytes, which was markedly decreased when they were pre-absorbed with commercial antiserum. Whole-cell clamp results showed an increase in the sodium current, and a retardation of the time course of inactivation, implicating the presence of an a toxin in both venoms. en
dc.description.librarian mn2013
dc.identifier.citation Van Aarde, MN, Van Rooyen, JM & Van Aswegen, G 1996, 'Screening of the venoms of two Parabuthus scorpion species on isolated cardiomyocytes’. Onderstepoort Journal of Veterinary Research, vol. 63, no. 2, pp. 127-130. en
dc.identifier.issn 0330-2465
dc.identifier.uri http://hdl.handle.net/2263/22070
dc.language.iso en en
dc.publisher Published by the Agricultural Research Council, Onderstepoort Veterinary Institute en
dc.rights © ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital). en
dc.subject Veterinary medicine en
dc.subject Cardiomyocytes en
dc.subject Parabuthus granulatus en
dc.subject Parabuthus transvaalicus en
dc.subject Scorpions en
dc.subject Venom en
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title Screening of the venoms of two Parabuthus scorpion species on isolated cardiomyocytes en
dc.type Article en


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