Subcellular localization of the nonstructural protein NS3 of African horsesickness virus

Stoltz, M.A.; Van der Merwe, Christiaan F.; Coetzee, J.; Huismans, H. (Henk), 1942-

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dc.contributor.author	Stoltz, M.A.
dc.contributor.author	Van der Merwe, Christiaan F.
dc.contributor.author	Coetzee, J.
dc.contributor.editor	Verwoerd, Daniel Wynand
dc.contributor.upauthor	Huismans, H. (Henk), 1942-
dc.date.accessioned	2013-08-15T10:51:55Z
dc.date.available	2013-08-15T10:51:55Z
dc.date.created	2013
dc.date.issued	1996
dc.description	The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat X Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.	en
dc.description.abstract	The subcellular localization of the minor nonstructural protein NS3 of African horsesickness virus (AHSV) has been investigated by means of immunogold electron-microscopical analysis. NS3 was observed in perturbed regions of the plasma membrane of AHSV-infected VERO cells, and its presence appears to be associated with events of viral release. These events are budding, whereby released viruses acquire fragments from the host-cell membrane, as well as by the extrusion of nonenveloped particles through the cell membrane. The membrane association of NS3 was confirmed by its detection in the disrupted plasma membranes of cells infected with an NS3 baculovirus recombinant. The absence of NS3 on intact cell membranes suggests that the protein is not exposed extracellularly.	en
dc.description.librarian	mn2013
dc.identifier.citation	Stoltz, MA, Van der Merwe, CF, Coetzee, J & Huismans, H 1996, 'Subcellular localization of the nonstructural protein NS3 of African horsesickness virus’. Onderstepoort Journal of Veterinary Research, vol. 63, no. 1, pp. 57-61.	en
dc.identifier.issn	0330-2465
dc.identifier.uri	http://hdl.handle.net/2263/22034
dc.language.iso	en	en
dc.publisher	Published by the Agricultural Research Council, Onderstepoort Veterinary Institute	en
dc.rights	© ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital).	en
dc.subject	Veterinary medicine	en
dc.subject	African horsesickness virus (AHSV)	en
dc.subject	Non-structural protein 3 (NS3)	en
dc.subject	NS3	en
dc.subject	Subcellular localization	en
dc.subject.lcsh	Veterinary medicine -- South Africa
dc.subject.lcsh	African horse sickness -- South Africa	en
dc.title	Subcellular localization of the nonstructural protein NS3 of African horsesickness virus	en
dc.type	Article	en