The potential impact of highly active antiretroviral therapy on the treatment and epidemiology of ranula in human immunodeficiency virus-positive patients

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dc.contributor.author Syebele, Kabunda
dc.contributor.author Munzhelele, Thifhelimbilu I.
dc.date.accessioned 2013-07-04T07:23:17Z
dc.date.available 2013-07-04T07:23:17Z
dc.date.issued 2013-06
dc.description.abstract OBJECTIVE: The study's aim was to assess the potential therapeutic effect of highly active antiretroviral therapy (HAART) on ranulas in human immunodeficiency virus (HIV)-positive patients. STUDY DESIGN: The study includes a retrospective observation of 3 patients who were initially part of a prospective study on the comparative effect of HAART on ranulas in 14 HIV-positive patients. These patients were clinically monitored while pursuing the medical treatment with HAART. Neither a fine needle aspiration nor a surgical procedure was performed. Clinical photographs were used for monitoring of any reduction in the ranula size. The effect of HAART on ranula was assessed at 3, 6 and 12 month. RESULTS: A complete resolution of the ranula lesion was noticed in the 3 HIV-positive selected patients. These results were observed between 6 and 12 months period. CONCLUSION: This study suggests that HAART might present a potential therapeutic effect on ranula in HIV-positive patients. en_US
dc.description.librarian hb2013 en_US
dc.description.uri http://www.sciencedirect.com/science/journal/22124403 en_US
dc.identifier.citation Syebele, K & Munzhelele, TI 2013, 'The potential impact of highly active antiretroviral therapy on the treatment and epidemiology of ranula in human immunodeficiency virus-positive patients', Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, vol. 116, no. 1, pp. e32-e36. en_US
dc.identifier.issn 2212-4403 (print)
dc.identifier.other 10.1016/j.oooo.2013.02.016
dc.identifier.uri http://hdl.handle.net/2263/21816
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.rights © 2013 Elsevier. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology.Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, vol. 116, no. 1, 2013, DOI : 10.1016/j.oooo.2013.02.016 en_US
dc.subject Antiretroviral therapy (ART) en_US
dc.subject Epidemiology en_US
dc.subject Ranula in HIV-positive patients en_US
dc.title The potential impact of highly active antiretroviral therapy on the treatment and epidemiology of ranula in human immunodeficiency virus-positive patients en_US
dc.type Postprint Article en_US


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