Abstract:
Despite available guidelines on indications for fresh-frozen plasma
(FFP) transfusion, inappropriate use is increasing worldwide. We
evaluated FFP administration to patients admitted to the Steve Biko
Academic Hospital over 4 months, including indications for use and
completeness of requisition forms. Transfusions were considered
inappropriate for 39.5% of units administered. Of request forms
submitted, only 22% had sufficient information for the blood
transfusion services of the indication for transfusion. Transfusion
with FFP is a medical intervention that carries risks and should
be undertaken with care. Although this study was conducted in
one centre, it is evident that clinicians’ lack of knowledge of the
indications for administration of FFP is widespread. Intervention
is necessary to improve patient outcomes and reduce expenditure.
