Mercier, Anne Elisabeth; Joubert, Anna Margaretha; Viallet, Jean; Desroches-Castan, Agnes; De Koning, Leanne; Mabeta, Peaceful Lucy; Helena, Jolene Michelle; Pepper, Michael Sean; Lafanechere, Laurence
(MDPI, 2024-10)
The microtubule-disrupting agent 2-methoxyestradiol (2-ME) displays anti-tumor and
anti-angiogenic properties, but its clinical development is halted due to poor pharmacokinetics. We
therefore designed two 2-ME analogs ...