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Research Articles (Immunology)
Recent Submissions
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Joseph, Darren; Theron, Annette J.; Feldman, C.; Anderson, Ronald; Tintinger, Gregory Ronald
(Taylor and Francis Group, 2024-12)
The recent global resurgence of severe infections caused by the Group A streptococcus (GAS) pathogen,
Streptococcus pyogenes, has focused attention on this microbial pathogen, which produces an array of
virulence factors, ...
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Levy-Storms, Lene; Lee, Soohyoung Rain; Castelyn, C. de Villebois; Morrissey, Mary Beth; Ory, Marcia G.
(Frontiers Media, 2025-02)
This Research Topic offers insights into various social determinants of health among older adults across the world, particularly in the context of pandemics and disaster environments. In this Research Topic, health is ...
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Smit, Chane; Robinson, Liam; Van Heerden, M.B. (Marlene); Meyer, Pieter Willem Adriaan; Ogunsakin, Ropo Ebenezer; Fonseca, Felipe Paiva; Uys, Andre; Van Heerden, Willem Francois Petrus
(Elsevier, 2024-09)
OBJECTIVES: This study aimed to analyze the clinicoradiologic features and Ki-67 proliferation indices between the histopathologic
variants of ameloblastomas (ABs) for possible associations.
STUDY DESIGN: The diagnosis ...
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Feldman, Charles; Theron, Annette J.; Cholo, Moloko C.; Anderson, Ronald
(MDPI, 2024-02)
It has been noted by the World Health Organisation that cases of tuberculosis in 2022
globally numbered 10.6 million, resulting in 1.3 million deaths, such that TB is one of the infectious
diseases causing the greatest ...
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Labuschagne Naidoo, Robyn-Brooke; Steel, Helen C.; Theron, Annette J.; Anderson, Ronald; Tintinger, Gregory Ronald; Rossouw, Theresa M.
(MDPI, 2024-06)
Please read abstract in article.
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Koatale, Palesa Caroline; Welling, Mick M.; Mdanda, Sipho; Mdlophane, Amanda; Takyi-Williams, John; Durandt, Chrisna; Van den Bout, Iman; Cleeren, Frederik; Sathekge, Mike Machaba; Ebenhan, Thomas
(MDPI, 2024-09)
Please read abstract in article.
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Matsoukas, Minos-Timotheos; Radomsky, Tarryn; Panagiotopoulos, Vasilis; Du Preez, Robin; Papadourakis, Michail; Tsianakas, Konstantinos; Millar, Robert P.; Anderson, Ross Calley; Spyroulias, Georgios A.; Newton, Claire L.
(American Chemical Society, 2024-08-29)
The growth hormone-releasing hormone receptor (GHRHR) belongs to Class B1 of G protein-coupled receptors
(GPCRs). Class B1 GPCR peptides such, as growth hormone-releasing hormone (GHRH), have been proposed to bind in a ...
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Wang, Yan; Allsop, Matthew J.; Epstein, Joel B.; Howell, Doris; Rapoport, Bernardo Leon; Schofield, Penelope; Van Sebille, Ysabella; Thong, Melissa S.Y.; Walraven, Iris; Wolf, Julie Ryan; Van den Hurk, Corina J.G.
(Springer, 2024-03)
PURPOSE : This paper aims to provide a comprehensive understanding of the need for continued development of symptom monitoring (SM) implementation, utilization, and data usage at the macro-, meso-, and micro-levels.
METHODS ...
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Smit, Chane; Robinson, Liam; Van Heerden, Marlene B.; Meyer, Pieter Willem Adriaan; Fonseca, Felipe P.; Van Heerden, Willem Francois Petrus; Uys, Andre
(Wiley, 2025-01)
BACKGROUND : The study aimed to assess the radiologic-specific growth rate of ameloblastomas, evaluating potential associations with demographics, radiologic features, histopathologic variants and proliferation indices. ...
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Feldman, Charles; Anderson, Ronald
(Elsevier, 2025-03)
Community-acquired pneumonia (CAP) continues to be a cause of significant morbidity and mortality worldwide. Much recent attention in this area of research has been focused on host factors associated with the infection. ...
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Mmakola, Khomotso Madimetsa Shelboy; Balmith, Marissa [; Steel, Helen C.; Said, Mohamed; Potjo, Moliehi; Van der Mescht, Mieke Adri; Hlatshwayo, Nomsa; Meyer, Pieter Willem Adriaan; Tintinger, Gregory Ronald; Anderson, Ronald; Cholo, Moloko C.
(MDPI, 2024-12-04)
Multidrug-resistant tuberculosis (MDR-TB) patients are treated with a standardised, short
World Health Organization (WHO) regimen which includes clofazimine (CFZ) and bedaquiline
(BDQ) antibiotics. These two antibiotics ...
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He, Huanqi; Huo, Linxuan; Oosthuizen-Vosloo, Solize; Pieper, Kelsey J.; Stubbins, Aron; Yoon, Byungman; Pinto, Ameet J.
(Elsevier, 2025-05)
Building plumbing microbial communities can significantly influence water quality at the point of use, particularly during periods of stagnation. Thus, a fine-scale understanding of factors governing community membership ...
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Holborn, Megan A.; Mellet, Juanita; Joubert, Fourie; Ballot, D.; Pepper, Michael Sean
(Elsevier, 2025-04)
Within the last decade, several studies have explored whether there might be a genetic component in hypoxic-ischaemic encephalopathy (HIE) that influences susceptibility to or outcomes following hypoxic-ischaemic injury. ...
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Van der Mescht, Mieke Adri; Steel, Helen C.; Anderson, Ronald; Rossouw, Theresa M.
(Frontiers Media S.A., 2025-02)
This review article discusses the role of vascular endothelial growth factor A (VEGF-A) in the pathogenesis of SARS-CoV-2 and HIV infection, both conditions being renowned for their impact on the vascular endothelium. The ...
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Van Niekerk, Andre
(Allergy Society of South Africa, 2024-03)
It was around 1973. Two years after the birth of David Vetter. David’s story captivated the mainstream media and the hearts of those who followed his sad case. He suffered from severe combined immunodeficiency (SCID) and his ...
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Van der Mescht, Mieke Adri; Steel, Helen C.; De Beer, Zelda; Masenge, Andries; Abdullah, Fareed; Ueckermann, Veronica; Anderson, Ronald; Rossouw, Theresa M.
(MDPI, 2024-11)
Whether SARS-CoV-2 infection leads to a higher mortality and morbidity in people living
with HIV (PLWH) in Africa remains inconclusive. In this study, we explored the differences in the
T-cell phenotypes between people ...
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Kahts, Maryke; Mellet, Juanita; Durandt, Chrisna; Moodley, Kinosha; Summers, Beverley; Ebenhan, Thomas; Zeevaart, Jan Rijn; Aras, Omer; Pepper, Michael Sean
(SpringerOpen, 2024-11)
Please read abstract in article.
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Ambele, Melvin Anyasi; Maebele, Lorraine Tshegofatso; Mulaudzi, Thanyani Victor; Kungoane, Tsholofelo; Damane, Botle Precious
(SpringerOpen, 2024-12)
Glioblastoma (GBM) is an aggressive brain tumor characterized by cellular and molecular diversity. This diversity presents
significant challenges for treatment and leads to poor prognosis. Surgery remains the primary ...
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Mistry, Priyal; Potgieter, Joachim; Pepper, Michael Sean; Durandt, Chrisna
(Springer, 2025-04)
Human immunodeficiency virus (HIV-1) infection remains a significant global public health concern, particularly in sub-Saharan Africa where the majority of HIV-1 infections are concentrated. People living with HIV (PLWH) ...
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Sudarshan, Ashwin S.; Dai, Zihan; Gabrielli, Marco; Oosthuizen-Vosloo, Solize; Konstantinidis, Konstantinos T.; Pinto, Ameet J.
(American Chemical Society, 2024-09)
Genome-resolved insights into the structure and function of the drinking water microbiome can advance the effective
management of drinking water quality. To enable this, we constructed and curated thousands of ...
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