- UPSpace Home
- →
- Health Sciences
- →
- Physiology
- →
- Research Articles (Physiology)
- →
- Recent submissions
JavaScript is disabled for your browser. Some features of this site may not work without it.
Research Articles (Physiology): Recent submissions
Now showing items 21-40 of 467
-
(MDPI, 2023-06)Immune checkpoint inhibitors (ICIs) are a class of immunotherapy agents capable of alleviating the immunosuppressive effects exerted by tumorigenic cells. The programmed cell death protein 1 (PD-1)/programmed death-ligand ...
-
(MDPI, 2023-02)Radiation resistance and radiation-related side effects warrant research into alternative strategies in the application of this modality to cancer treatment. Designed in silico to improve the pharmacokinetics and anti-cancer ...
-
(Wiley, 2024-06)CTCE-9908, a CXC chemokine receptor 4 (CXCR4) antagonist, prevents CXCR4 phosphorylation and inhibits the interaction with chemokine ligand 12 (CXCL12) and downstream signalling pathways associated with metastasis. This ...
-
(Wiley, 2023-10)The prevalence of breast cancer (BC) continues to increase and is the leading cause of cancer deaths in many countries. Numerous in vitro and in vivo studies have demonstrated that 2‐methoxyestradiol (2‐ME) has ...
-
(Wiley, 2023-10)The metastatic behavior of melanoma has accentuated the need for specific therapy targets. Compounds, namely L‐kynurenine (L‐kyn), quinolinic acid (Quin), and kynurenic acid (KA) previously displayed antiproliferative ...
-
(Elsevier, 2024-02)The nuclear envelope separates the genome from the cytoplasmic environment. However, the nuclear envelope is also physically associated with the genome and exerts influence on gene expression and genome modification. The ...
-
(MDPI, 2023-03)BACKGROUND : Non-communicable diseases are often associated with chronic inflammation, placing patients suffering from these conditions at a higher risk of thrombosis and other complications. The pathophysiology of asthma ...
-
(Lippincott Williams and Wilkins, 2023-09)OBJECTIVE : To determine independent risk factors associated with a history of exercise-associated muscle cramps (hEAMCs) in distance runner race entrants in a community-based mass participation event. DESIGN : ...
-
(MDPI, 2023-05-19)Three-dimensional cell culture models are increasingly adopted as preferred pre-clinical drug testing platforms, as they circumvent limitations associated with traditional monolayer cell cultures. However, many of these ...
-
(Wiley, 2024-03)Melanoma, an invasive class of skin cancer, originates from mutations in melanocytes, the pigment-producing cells. Globally, approximately 132,000 new cases are reported each year, and in South Africa, the incidence stands ...
-
(Wiley, 2023-11)OBJECTIVE : To investigate the frequency and trajectories of individual patients with polyarticular-course juvenile idiopathic arthritis (JIA) achieving novel composite end points on abatacept. METHODS : Data from a ...
-
(Oxford University Press, 2023-09)Please read abstract in the article.
-
(Routledge, 2023)Identifying coordination strategies used by sprinters and features that differentiate these strategies will aid in understanding different technical approaches to initial sprint acceleration. Moreover, multiple effective ...
-
(Taylor and Francis, 2024)OBJECTIVES : Currently, there are five international screening tools that are recommended to identify individuals who require pre-exercise medical clearance to reduce the risk of medical encounters during exercise. Therefore, ...
-
(Sage, 2023)BACKGROUND : Haemophilia A (HA) is a bleeding disorder, due to a deficiency in factor VIII (FVIII). These patients are unable to produce a stable fibrin clot in the propagation phase of coagulation as they do not generate ...
-
(Elsevier, 2024-01)OBJECTIVES : Determine the epidemiology and clinical characteristics of training and match injuries in university student rugby players over a two-season period. DESIGN : Prospective cohort. SETTING : Varsity Cup (VC) ...
-
(Elsevier, 2024-01)BACKGROUND : Venomous snake bites have been listed as a neglected tropical disease by the World Health Organization. The Mozambique spitting cobra (Naja mossambica) is found in Sub-Saharan African countries, and its venom ...
-
(Wiley, 2024-01)The generation of tissue from stem cells is an alluring concept as it holds a number of potential applications in clinical therapeutics and regenerative medicine. Mesenchymal stromal/stem cells (MSCs) can be isolated from ...
-
(Elsevier, 2023-12)Diabetes mellitus is a prevalent non-communicable disease affecting individuals in developed and developing countries. However, low-income countries face significant challenges in managing diabetes due to socio-economic ...
-
(Taylor and Francis, 2023)Exposure to environmental metal pollutants is linked to oxidative stress and the subsequent development of neurological disease. In this study, the effects of copper, manganese, and mercury, were evaluated at X100 the World ...
Now showing items 21-40 of 467