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Browsing Physiology by Type "Thesis"
Now showing items 1-19 of 19
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(University of Pretoria, 2023)Initial sprint acceleration is a complex and dynamic skill, requiring the application of large forces to propel the body forwards. Effective force application is achieved through the use of joint and segment rotations in ...
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(University of Pretoria, 2006-10-03)In this study we evaluated the validity of well-known human electrocardiographic markers of myocardial pathology in Dorper sheep. These markers are all properties of PVC`s, namely the duration of the QRS complex of PVC`s, ...
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Development of a breast cancer spheroid model for use in drug discovery and cancer biology research (University of Pretoria, 2020)The screening of lead compounds during cancer drug discovery still results in many hits that never reach the clinic. This is in part due to the distance between 2D cell culture, which is mostly used for screening assays ...
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(University of Pretoria, 2013)Introduction: Education of physiotherapists still fails to meet the health and social needs of society. One instrument to steer change in health sciences education is a re-designed curriculum. The overall intent of this ...
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(University of Pretoria, 2014)Microtubule-disrupting agents have been studied for decades for their potential anticancer activity and resulted in discovery of an endogenous 17β-estradiol derivative, 2-methoxyestradiol (2ME2). Since 2ME2 possesses low ...
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(University of Pretoria, 2006-03-09)The purpose of the study was to elucidate the mechanisms by which polyunsaturated fatty acids (PUFAs) prevent bone loss. MG-63 human osteoblasts and MC3T3-E1 murine osteoblasts were exposed to the n-6 PUFA arachidonic acid ...
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(University of Pretoria, 2015)The essential amino acid tryptophan is an important substrate for the synthesis of serotonin, melatonin, tryptamine, proteins and the kynurenines. The aim of this study was to investigate tryptophan metabolism along the ...
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(University of Pretoria, 2019)Inflammation is a well-known underlying cause in many diseases. Chronic inflammation has a role in a host of common and often deadly diseases, including Alzheimer’s disease, rheumatoid arthritis, cancer, type 2 diabetes, ...
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(University of Pretoria, 2011)The study dealt with the influence of exercise on the autonomic nervous system (ANS) and with factors that may influence the results. ANS function was measured in 183 young, healthy participants, before and after a twelve ...
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(University of Pretoria, 2009-04-07)Angiogenesis, the process of new vessel formation, appears to be a central mechanism that underlies the development of haemangiomas. Recently, intralesional bleomycin injection was used to treat paediatric haemangiomas ...
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(University of Pretoria, 2018)Background: The underlying risk factor of non-communicable diseases is inflammation. The pathophysiology of asthma and/or allergic asthma is also, no surprisingly, also linked to chronic inflammation. The prevalence and ...
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(University of Pretoria, 2020)Therapeutic inefficacy of conventional cancer treatment is a particular dilemma associated with metastatic triple negative breast cancer (TNBC), with patients still facing poor prognosis. The design and development of novel ...
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(University of Pretoria, 2009)Ferritin is the major protein responsible for the sequestration, storage and release of intracellular iron. The ferritin protein shell exists as heteropolymers of various combinations of two types of subunits, the H-subunit ...
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(University of Pretoria, 2005-01-09)The immunological effects of mycolic acids (MA) from Mycobacterium tuberculosis on mouse peritoneal macrophages were studied. MA was solubilbized using various carriers. Phagosome uptake and maturation (into late stage ...
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(University of Pretoria, 2014)Most cancer cells rely on aerobic glycolysis to support the mitochondrial oxidative phosphorylation system (OXPHOS). The persistent oxic-anoxic cycle exerts selection pressures which lead to constitutive activation of ...
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(University of Pretoria, 2016)Diabetes mellitus has emerged as a major public health problem with pandemic growth as the International Diabetes Federation estimates that there were 415 million diabetics in 2015 with that number reaching 642 million ...
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(University of Pretoria, 2020)Introduction Sleep apnea is classified as a sleep disorder characterized by a complete cessation, known as apneas, or impairment (partial cessation) of breathing, known as hypopneas. During obstructive sleep apnea (OSA), ...
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(University of Pretoria, 2008-02-06)Please read the abstract in the section, 00front of this document
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(University of Pretoria, 2013)INTRODUCTION: The menstrual cycle and pregnancy are processes unique to women. Both these processes involve various hormones as well as the coagulation system. Throughout normal pregnancy, platelet activation and increase ...
Now showing items 1-19 of 19