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Research Articles (Medical Microbiology): Recent submissions
Now showing items 101-120 of 384
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(Taylor and Francis, 2022)A fully liquid MenACWY-CRM vaccine presentation has been developed, modifying the meningococcal serogroup A (MenA) component from lyophilized to liquid. The safety and immunogenicity of the liquid presentation at the end ...
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(BMJ Publishing Group, 2021-03)OBJECTIVES: Macrolide resistance in Mycoplasma genitalium is emerging globally. There is paucity of data from sub-Saharan Africa where syndromic management is used to treat sexually transmitted infections (STIs). We conducted ...
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(BMJ Publishing Group, 2021-12)No abstract available.
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(Lippincott Williams and Wilkins, 2021-02)We conducted an observational study of lymphogranuloma venereum (LGV) biovar Chlamydia trachomatis infection in HIV-infected women in South Africa. The LGV biovar was detected in vaginal specimens of 17 (20%) of 85 women ...
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(Public Library of Science, 2022-08-04)OBJECTIVE : We aimed to provide an analysis of A. baumannii complex (ABC) isolated from blood cultures in South Africa. MATERIALS AND METHODS : ABC surveillance was conducted from 1 April 2017 to 30 September 2019 at ...
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(Frontiers Media S.A., 2022-08-26)BACKGROUND : Mobile colistin resistance (mcr) genes modify Lipid A molecules of the lipopolysaccharide, changing the overall charge of the outer membrane. RESULTS AND DISCUSSION: Ten mcr genes have been described to date ...
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(Nature Research, 2021-10-20)Mycobacterium tuberculosis is a clonal pathogen proposed to have co-evolved with its human host for millennia, yet our understanding of its genomic diversity and biogeography remains incomplete. Here we use a combination ...
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(Frontiers Media S.A., 2022-06-09)Human leukocyte antigens (HLA) diversity has a tremendous impact on shaping the transplantation practices, transfusion-associated graft versus host disease prevention strategies, and host–pathogen interactions. Here, we ...
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(Journal of Clinical Microbiology, 2022-07)Ceftazidime-avibactam, meropenem-vaborbactam, and imipenem-relebactam are among the newest b-lactam/b-lactamase inhibitors (BL/BLIs) introduced to the North American antibiotic market. All have broad Gram-negative activity, ...
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(SA MEDICAL ASSOC, 2021-10)BACKGROUND. Reports have emerged globally of antimicrobial resistance (AMR) in Neisseria gonorrhoeae and Mycoplasma genitalium infections. In South Africa (SA), there are substantial differences between private and public ...
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(Elsevier, 2021-11)Spinal epidural abscess caused by Aspergillus spp is a debilitating form of invasive aspergillosis that can easily be misdiagnosed as spinal tuberculosis due to shared risk factors and clinical features. In this Grand ...
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(Health and Medical Publishing Group, 2021-04)No abstract available.
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(Health and Medical Publishing Group, 2021-02)BACKGROUND. Pneumococcal carriage studies provide a baseline for measuring the impact of pneumococcal conjugate vaccines (PCVs). The advent of conjugate vaccines has led to reductions in vaccine serotypes (VTs) in ...
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(Elsevier, 2021-08)BACKGROUND : Current tuberculosis treatments leave patients with clinically significant lung injury and increased all-cause mortality post-cure. Adjunctive host-directed therapies could protect the lungs, improve long-term ...
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Indicator-focussed technical assistance in South Africa’s HIV programme : a stepped-wedge evaluation (AOSIS, 2021-06-15)BACKGROUND : There is a lack of research on technical assistance (TA) interventions in low- and middle-income countries. Variation in local contexts requires tailor-made approaches to TA that are structured and replicable ...
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(BMJ Publishing Group, 2021-08)OBJECTIVE : STIs during pregnancy increase adverse pregnancy and birth outcomes and may increase HIV risk. STI syndromic management is standard of care in South Africa. Our study evaluated the prevalence and incidence of ...
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(American Society for Microbiology, 2021-12-22)Escherichia coli is a leading cause of community-acquired and health careassociated bloodstream infections (BSIs) worldwide. Limited information is available regarding the changes in population dynamics of human E. coli ...
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(Elsevier, 2021-08)Bedaquiline, a novel therapeutic drug, and clofazimine, a re-purposed drug, are front-line therapies recommended by WHO to treat rifampicin-resistant or multidrugresistant tuberculosis. Both drugs have been in use ...
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(Wiley, 2022-03)Antimicrobial resistance (AMR) is a public health threat globally. Carbapenems are β-lactam antibiotics used as last-resort agents for treating antibiotic-resistant infections. Mobile genetic elements (MGEs) play an important ...
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(Frontiers Media SA, 2022-02-22)Patients who complete a standard course of anti-tuberculous treatment (ATT) for pulmonary tuberculosis and are declared cured according to the current standard of care commonly have residual metabolic activity (RMA) in ...
Now showing items 101-120 of 384