Medical Microbiology: Recent submissions

Now showing items 81-100 of 426

High levels of pretreatment HIV-1 drug resistance mutations among South African women who acquired HIV during a prospective study

Beesham, Ivana; Parikh, Urvi M.; Mellors, John W.; Davey, Dvora L. Joseph; Heffron, Renee; Palanee-Phillips, Thesla; Bosman, Shannon L.; Beksinska, Mags; Smit, Jennifer; Ahmed, Khatija; Makkan, Heeran; Selepe, Pearl; Louw, Cheryl; Kotze, Philip; Hofmeyr, G. Justus; Singata-Madliki, Mandisa; Rees, Helen; Baeten, Jared M.; Wallis, Carole (Lippincott Williams and Wilkins, 2022-10)

BACKGROUND : Pretreatment HIV drug resistance (PDR) undermines individual treatment success and threatens the achievement of UNAIDS 95-95-95 targets. In many African countries, limited data are available on PDR as detection ...
Estimating the global burden of sexually transmitted infections

Peters, Remco P.H.; Chico, R. Matthew; Rowley, Jane; Low, Nicola (Elsevier, 2022-08)

No abstract available.
Prevalence of bacteriologically confirmed pulmonary tuberculosis in South Africa, 2017-19 : a multistage, cluster-based, cross-sectional survey

Moyo, Sizulu; Ismail, Farzanah; Van der Walt, Martie; Ismail, Nazir Ahmed; Mkhondo, Nkateko; Dlamini, Sicelo; Mthiyane, Thuli; Chikovore, Jeremiah; Oladimeji, Olanrewaju; Mametja, David; Maribe, Phaleng; Seocharan, Ishen; Ximiya, Phumlani; Law, Irwin; Tadolini, Marina; Zuma, Khangelani; Manda, S.O.M. (Samuel); Sismanidis, Charalambos; Pillay, Y.; Mvusi, Lindiwe (Elsevier, 2022-08)

BACKGROUND : Tuberculosis remains an important clinical and public health issue in South Africa, which has one of the highest tuberculosis burdens in the world. We aimed to estimate the burden of bacteriologically confirmed ...
Treatment outcomes 24 months after initiating short, all-oral bedaquiline-containing or injectable-containing rifampicin-resistant tuberculosis treatment regimens in South Africa : a retrospective cohort study

Ndjeka, Norbert; Campbell, Jonathon R.; Meintjes, Graeme; Maartens, Gary; Schaaf, H. Simon; Hughes, Jennifer; Padanilam, Xavier; Reuter, Anja; Romero, Rodolfo; Ismail, Farzanah; Enwerem, Martin; Ferreira, Hannetjie; Conradie, Francesca; Naidoo, Kogieleum; Menzies, Dick (Elsevier, 2022-07)

BACKGROUND : There is a need for short and safe all-oral treatment of rifampicin-resistant tuberculosis. We compared outcomes up to 24 months after treatment initiation for patients with rifampicin-resistant tuberculosis ...
Development of simple and effective PCR based assay to detect PCCA mutation (c.425G > A) among Saudi carriers and functional study of the homozygous PCCA mutations

Al-Asmari, Ali; Peer-Zada, Abdul Ali; AlDehaimi, Abdulwahed; Polychronakos, Constantin; Chentoufi, Aziz Alami (Elsevier, 2022-12)

The aim of this study is to develop a rapid and effective method to screen for Saudi carriers of one of the most common propionic acidemia mutations (c.425G > A) and to study the functional impact of this mutation. Using ...
Faecal carriage of ESBL producing and colistin resistant Escherichia coli in avian species over a 2-year period (2017-2019) in Zimbabwe

Takawira, Faustinos Tatenda; Pitout, Johann D.D.; Thilliez, Gaetan; Mashe, Tapfumanei; Gutierrez, Ana Victoria; Kingsley, Robert A.; Peirano, Gisele; Matheu, Jorge; Midzi, Stanley Munyaradzi; Mwamakamba, Lusubilo Witson; Gally, David L.; Tarupiwa, Andrew; Mukavhi, Leckson; Ehlers, M.M. (Marthie Magdaleen); Mtapuri-Zinyowera, Sekesai; Kock, Marleen M. (Frontiers Media, 2022-12-23)

INTRODUCTION : Extended spectrum beta-lactamase (ESBL) producing Escherichia coli have become widespread among food producing animals. These strains serve as a reservoir of antibiotic resistance genes (ARGs) and act as ...
In vitro anti-biofilm effects of Loxostylis alata extracts and isolated 5-demethyl sinensetin on selected foodborne bacteria

Gado, Dorcas A.; Abdalla, Muna Ali; Erhabor, Joseph Omorogiuwa; Ehlers, M.M. (Marthie Magdaleen); McGaw, Lyndy Joy (Elsevier, 2023-05)

Bacterial biofilms pose health challenges both in clinical environments and the food industry. Major foodborne bacterial pathogens form biofilms on surfaces and persist, causing infections in humans that may be difficult ...
Pharmacological properties and radical scavenging potential of 5-demethyl sinensetin obtained from Loxostylis alata

Gado, Dorcas A.; Abdalla, Muna Ali; Ehlers, M.M. (Marthie Magdaleen); McGaw, Lyndy Joy (Elsevier, 2023-05)

Please read abstract in the article.
Population-based surveillance of Enterobacter cloacae complex causing blood stream infections in a centralized Canadian region

Stokes, William; Peirano, Gisele; Matsumara, Yasufumi; Nobrega, Diego; Pitout, Johann D.D. (Springer, 2022-01)

Active population-based surveillance determined clinical factors, susceptibility patterns, incidence rates (IR), and genomics among Enterobacter cloacae complex (n = 154) causing blood stream infections in a centralized ...
Genomic epidemiology of global carbapenemase-producing Escherichia coli, 2015–2017

Peirano, Gisele; Chen, Liang; Nobrega, Diego; Finn, Thomas J. (Centers for Disease Control and Prevention, 2022-05)

We describe the global molecular epidemiology of 229 carbapenemase-producing Escherichia coli in 36 countries during 2015–2017. Common carbapenemases were oxacillinase (OXA) 181 (23%), New Delhi metallo-β-lactamase (NDM) ...
Genotypic profiles of emerging multidrug-resistant Staphylococcus capitis isolates from an ongoing outbreak in critically ill patients

Mynhardt, Barend J. (University of Pretoria, 2023)

An increasing number of linezolid resistant (LZR), multidrug-resistant (MDR) Staphylococcus capitis infections have been observed in private hospitals in the greater Gauteng area since 2014. The aim of this study was to ...
Case-fatality and sequelae following acute bacterial meningitis in South Africa, 2016 through 2020

Meiring, Susan; Cohen, Cheryl; De Gouveia, Linda; Du Plessis, Mignon; Quan, Vanessa; Kleynhans, Jackie; Menezes, Colin; Reubenson, Gary; Dawood, Halima; Nchabeleng, Maphoshane; Said, Mohamed; Mvelase, Nomonde; Mahabeer, Prasha; Chomba, Rispah; Lekalakala, Ruth; Nana, Trusha; Chibabhai, Vindana; Black, Marianne; Von Gottberg, Anne (Elsevier, 2022-09)

OBJECTIVES : Providing country-specific estimates of case fatality and sequelae from bacterial meningitis (BM) is important to evaluate and monitor progress toward the World Health Organization's roadmap to “defeating ...
Outbreak and control of Achromobacter denitrificans at an academic hospital in Pretoria, South Africa

Said, Mohamed; Mitton, Barend; Skosana, Lebogang Busisiwe; Kopotsa, Katlego; Naidoo, Rashmika; Amutenya, Victoria (Cambridge University Press, 2023-01)

OBJECTIVE : In this study, we sought to determine the source of an outbreak of Achromobacter denitrificans infections in patients at a tertiary-care academic hospital. DESIGN : Outbreak report study with intervention. The ...
Characteristics and outcomes of patients admitted to a tertiary academic hospital in Pretoria with HIV and severe pneumonia : a retrospective cohort study

Ueckermann, Veronica; Janse van Rensburg, Luricke; Pannell, N.; Ehlers, Marthie Magdaleen (BMC, 2022-06-15)

BACKGROUND : Human immunodeficiency virus (HIV) contributes significantly to morbidity and mortality in South Africa. Pneumonia and opportunistic infections remain a major cause for hospital admission among those living ...
Importance of Candida infection and fluconazole resistance in women with vaginal discharge syndrome in Namibia

Dunaiski, Cara M.; Kock, Martha Magdalena; Jung, Hyunsul; Peters, Remco P.H. (BMC, 2022-08-15)

BACKGROUND : Vaginal discharge syndrome (VDS) is a common condition. Clinical management targets sexually transmitted infections (STIs) and bacterial vaginosis (BV); there is limited focus on Candida infection as cause ...
Stigma in the health clinic and implications for PrEP access and use by adolescent girls and young women : conflicting perspectives in South Africa

Nyblade, Laura; Ndirangu, Jacqueline W.; Speizer, Ilene S.; Browne, Felicia A.; Bonner, Courtney Peasant; Kline, Tracy L.; Ahmed, Khatija; Howard, Brittni N.; Cox, Erin N.; Rinderle, Abigail; Wechsberg, Wendee M. (BMC, 2022-10-14)

BACKGROUND : Globally, an urgent need exists to expand access to HIV prevention among adolescent girls and young women (AGYW), but the need is particularly acute in sub-Saharan Africa. Oral pre-exposure prophylaxis (PrEP) ...
PulseNet International survey on the implementation of whole genome sequencing in low and middle-income countries for foodborne disease surveillance

Davedow, Taylor; Carleton, Heather; Kubota, Kristy; Palm, Daniel; Schroeder, Morgan; Gerner-Smidt, Peter; Al-Jardani, Amina; Chinen, Isabel; Kam, Kai Man; Smith, Anthony Marius; Nadon, Celine (Mary Ann Liebert, 2022-05)

PulseNet International (PNI) is a global network of 88 countries who work together through their regional and national public health laboratories to track foodborne disease around the world. The vision of PNI is to implement ...
Genital inflammatory status and the innate immune response to contraceptive initiation

Radzey, Nina; Harryparsad, Rushil; Meyer, Bahiah; Chen, Pai Lien; Gao, Xiaoming; Morrison, Charles; Taku, Ongeziwe; Williamson, Anna-Lise; Mehou-Loko, Celia; Lefebvre d’Hellencourt, Florence; Buck, Gregory; Smit, Jennifer; Strauss, Jerome; Nanda, Kavita; Ahmed, Khatija; Beksinska, Mags; Serrano, Myrna; Bailey, Veronique; Masson, Lindi; Deese, Jennifer (Wiley, 2022-08)

PROBLEM : Data on the effects of contraceptives on female genital tract (FGT) immune mediators are inconsistent, possibly in part due to pre-existing conditions that influence immune mediator changes in response to ...
The importance of Escherichia coli clonal complex 10 and ST131 among Tanzanian patients on antimicrobial resistance surveillance programs

Seni, Jeremiah; Peirano, Gisele; Mshana, Stephen E.; Pitout, Johann D.D.; DeVinney, Rebekah (Springer, 2023)

Please read abstract in the article.
Population-based epidemiology of Escherichia coli ST1193 causing blood stream infections in a centralized Canadian region

Peirano, Gisele; Matsumara, Yasufumi; Nobrega, Diego; DeVinney, Rebekah; Pitout, Johann D.D. (Springer, 2023)

Please read abstract in the article.

Now showing items 81-100 of 426

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