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Medical Microbiology: Recent submissions
Now showing items 361-380 of 426
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(University of Pretoria, 2012-10-01)Multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR-TB) is a serious problem in South Africa. Standardised and accurate drug susceptibility testing for first-line and second-line anti-TB drugs are ...
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(University of Pretoria, 2012-08-14)Klebsiella pneumoniae is an important nosocomial pathogen that has the potential to cause severe morbidity and mortality, particularly in intensive care units, as well as in medical and surgical wards. In recent years, ...
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(University of Pretoria, 2012-08-08)Ureaplasma spp colonize the lower genital tract in many healthy men, yet can also cause urethritis and infertility. Since Ureaplasma spp are frequently isolated from the normal urogenital tract, it has been suggested ...
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(University of Pretoria, 2013-04-18)Sexually transmitted infections (STIs) are a major cause of acute illnesses, infertility, long term disability and death with far reaching health, social and economic consequences. Trichomonas vaginalis is the causative ...
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Genetic relatedness of methicillin resistant Staphylococcus aureus isolates from Steve Biko hospital (University of Pretoria, 2013-04-18)Methicillin resistant Staphylococcus aureus (MRSA) causes severe infections in humans. An estimated two billion people carry S. aureus worldwide, of which fifty-three million harbour MRSA strains. The ability of MRSA to ...
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(University of Pretoria, 2010-03-01)Methicillin-resistant Staphylococcus aureus (MRSA) is a pandemic human pathogen accounting for most of health-care associated infections throughout the world. However, in recent years, a more virulent strain of MRSA has ...
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(University of Pretoria, 2004)Extended-spectrum beta-lactamases (ESBLs) in Pseudomonas aeruginosa tend to be geographically scattered, such as GES-2, which partially compromises the efficacy of imipenem. The G170N mutation, ascribed to a CC to AA base ...
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(University of Pretoria, 2005-09-22)Please read the abstract in the front section of this document
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(University of Pretoria, 2008-09-25)Extended-spectrum β-lactamases (ESBLs) constitute a major problem given their broad substrate specificity and ability to hydrolyse many of the extended-spectrum third-generation cephalosporins currently in use in hospital ...
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(University of Pretoria, 2010-05-13)The World Health Organization (WHO) estimated that eight million new cases of tuberculosis (TB) occur every year and that one-third of the world’s population is infected with Mycobacterium tuberculosis (M. tuberculosis). ...
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Evaluation of a radiometrically-determined regrowth model for the study of anti-tuberculosis drugs (University of Pretoria, 1999)Background: A post-exposure regrowth model utilizing the well-tried Bactec radiometric system, which would simulate in vivo situations at the site of invasive disease, was developed to measure drug activity against multiplying ...
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(American Society for Microbiology, 2013-06)Multidrug-resistant tuberculosis (MDR-TB) threatens global TB control. The lengthy treatment includes one of the injectable drugs kanamycin, amikacin, and capreomycin, usually for the first 6 months. These drugs have ...
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(BioMed Central, 2012-12-22)BACKGROUND: The increasing problem of multi-drug-resistant (MDR) tuberculosis (TB) [ie resistant to at least isoniazid (INH) and rifampicin (RIF)] is becoming a global problem. Successful treatment outcome for MDR-TB depends ...
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Biting off more than you can chew : microbiological flora isolated from human and animal bite wounds (Media 24 & South African Orthopaedic Association, 2012)BACKGROUND: Bite wounds, from human and animal origin, can lead to significant complications if appropriate therapy is not undertaken timeously. A basic knowledge of the microbiological flora is essential for each clinical ...
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(American Society for Microbiology, 2012-09)Despite South Africa being one of the high-burden multidrug-resistant tuberculosis (MDR-TB) countries, information regarding the population structure of drug-resistant Mycobacterium tuberculosis strains is limited from ...
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(American Society for Microbiology, 2012-12)A novel protocol for full-length Mycobacterium tuberculosis gene analysis of first- and second-line drug resistance was developed using the Ion Torrent Personal Genome Machine (PGM). Five genes—rpoB (rifampin), katG ...
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(Elsevier, 2012)A new efficacious tuberculosis (TB) vaccine has the potential to dramatically assist control efforts for the global TB epidemic. Good progress has been made with the clinical development of new TB vaccine candidates with ...
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(BioMed Central, 2012-09-11)INTRODUCTION: Most individuals infected with human immunodeficiency virus-1, in the absence of antiretroviral therapy, exhibit persistent virus replication and declining CD4+ cell numbers, and progress to acquired ...
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(Federation of Infectious Diseases Societies of South Africa, 2012)The hypervirulent polymerase chain reaction (PCR) ribotype 027 strain of Clostridium difficile produces toxins A, B and a binary toxin. Toxin detection kits are commonly used in diagnostic laboratories, but have been ...
Now showing items 361-380 of 426