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Medical Microbiology: Recent submissions
Now showing items 301-320 of 426
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(University of Pretoria, 2016)Background. In recent years, there has been an alarming increase in cases of multidrug-resistant tuberculosis (MDR-TB), and also extensively drug-resistant tuberculosis (XDR-TB). The emergence of these forms of tuberculosis ...
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Marginal structural models to assess delays in second-line HIV treatment initiation in South Africa (Public Library of Science, 2016-08-22)BACKGROUND South African HIV treatment guidelines call for patients who fail first-line antiretroviral therapy (ART) to be switched to second-line ART, yet logistical issues, clinician decisions and patient preferences ...
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(BioMed Central, 2013-03)Tuberculosis (TB) remains a deadly infectious disease affecting millions of people worldwide; 95% of TB cases, with 98% of death occur in developing countries. The situation in South Africa merits special attention. A ...
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(BioMed Central, 2016-07-12)BACKGROUND : Sexual behaviour is a core determinant of the HIV and sexually transmitted infection (STI) epidemics in women living in rural South Africa. Knowledge of sexual behaviour in these areas is limited, but ...
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(Taylor and Francis, 2016-07)Carbapenemase-producing Enterobacteriaceae (CPE), mainly Klebsiella pneumoniae and Escherichia coli, have been increasing rapidly on a global scale and are considered to be significant health threats. The most common ...
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(Public Library of Science, 2016-04-26)Norovirus (NoV) is recognised as a leading cause of gastroenteritis worldwide across all age groups. The prevalence and diversity of NoVs in many African countries is still unknown, although early sero-prevalence studies ...
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(Public Library of Science, 2016-06-20)BACKGROUND Automated digital microscopy has the potential to improve the diagnosis of tuberculosis (TB), particularly in settings where molecular testing is too expensive to perform routinely. The cost-effectiveness of ...
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(American Society for Microbiology, 2016-08)The blaIMP-14 carbapenem resistance gene has largely previously been observed in Pseudomonas aeruginosa and Acinetobacter spp. As part of global surveillance and sequencing of carbapenem-resistant E. coli, we identified ...
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(SpringerOpen Journal, 2016-05)The purpose of this investigation was to determine the clinical and corneal microbial profile of infectious keratitis in a high human immunodeficiency virus (HIV) prevalence setting in rural South Africa. Data in this ...
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(Oxford University Press, 2016-06)During 2013, ST278 Klebsiella pneumoniae with blaNDM-7 was isolated from the urine (KpN01) and rectum (KpN02) of a patient in Calgary, Canada. The same strain (KpN04) was subsequently isolated from another patient in the ...
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(Taylor and Francis, 2016-05)The female genital tract is an intricate, yet balanced ecosystem that hosts a variety of different residential microflora. The physiological changes that occur during pregnancy may disrupt this balanced ecosystem and ...
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(Oxford University Press, 2016-05)OBJECTIVES : Extensive but fragmented data from existing studies were used to describe the drug-drug interaction between rifabutin and HIV-protease inhibitors, and predict doses achieving recommended therapeutic exposure ...
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(University of Pretoria, 2015)Tuberculosis (TB) is a major cause of death worldwide, especially in Asia and Africa. Genotyping methods such as insertion sequence 6110-restriction fragment length polymorphism (IS6110-RFLP), spoligotyping and mycobacterial ...
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(Taylor and Francis, 2016-07)Urinary tract infections (UTIs) are among the most common infectious diseases occurring in either the community or healthcare settings. A wide variety of bacteria are responsible for causing UTIs, however extra-intestinal ...
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(Public Library of Science, 2016-01-11)BACKGROUND In South Africa and other high prevalence countries, transmission is a significant contributor to rising rates of multidrug resistant tuberculosis (MDR-TB). Thus, there is a need to develop an early detection ...
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(Wiley, 2016-03)OBJECTIVES : To describe the spectrum of ocular complications of herpes zoster ophthalmicus (HZO) in rural South Africa. METHODS : Patients presenting with visual complaints and active or healed HZO at the ophthalmology ...
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(Lippincott, Williams and Wilkins, 2016-02)We report a case of progressive, cephalosporin-susceptible, Neisseria gonorrhoeae conjunctivitis despite successful treatment of male urethritis syndrome. We hypothesize that conjunctival infection progressed due to ...
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(Nature Publishing Group, 2015-12-21)The rise of antibiotic-resistant bacteria has led to an urgent need for rapid detection of drug resistance in clinical samples, and improvements in global surveillance. Here we show how de Bruijn graph representation of ...
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(Public Library of Science, 2015-12-31)INTRODUCTION We aimed to obtain an in-depth understanding on recent antimicrobial resistance trends and molecular epidemiology trends of S. aureus bacteraemia (SAB). METHODS Thirteen academic centres in South Africa ...
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(Elsevier, 2015-11)BACKGROUND : Tuberculous pericarditis is considered to be a paucibacillary process; the large pericardial fluid accumulation is attributed to an inflammatory response to tuberculoproteins.Mortality rates are high. ...
Now showing items 301-320 of 426