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Browsing Medical Microbiology by Type "Thesis"
Now showing items 1-11 of 11
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(University of Pretoria, 2016)Polymyxins have previously been described to have activity against M. tuberculosis (M. tb), but further research was abandoned due to systemic toxicity concerns to achieve the required MIC. Colistin methanesulfonate (CMS), ...
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(University of Pretoria, 2023)Antimicrobial resistance in Mycobacterium tuberculosis and Neisseria gonorrhoeae is emerging globally. Due to the limited treatment options, the World Health Organization has designated M. tuberculosis and N. gonorrhoeae ...
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(University of Pretoria, 2020)This study demonstrates the ability of a selected novel IgG1 mouse monoclonal antibody, JG7 III D3 I F9 (JG7), to enhance the phagocytic elimination (opsonophagocytosis) of susceptible M. tuberculosis strains at both their ...
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(University of Pretoria, 2012-10-01)Multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR-TB) is a serious problem in South Africa. Standardised and accurate drug susceptibility testing for first-line and second-line anti-TB drugs are ...
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(University of Pretoria, 2015)The global control of tuberculosis (TB) is currently hindered by the low sensitivity of microscopy and the prolonged time-to-result of culture. Recent technical progress has improved both diagnostic accuracy and turnaround, ...
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(University of Pretoria, 2004)Extended-spectrum beta-lactamases (ESBLs) in Pseudomonas aeruginosa tend to be geographically scattered, such as GES-2, which partially compromises the efficacy of imipenem. The G170N mutation, ascribed to a CC to AA base ...
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(University of Pretoria, 2020)Chronic obstructive pulmonary disease (COPD) is a leading cause of death and is highly prevalent in South Africa (19% in adults over the age of 40 years). Inflammation of the lungs in COPD impairs the immune response and ...
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(University of Pretoria, 2020-02)Antimicrobial resistance (AMR) in Neisseria gonorrhoeae has emerged worldwide and treatment failures of ceftriaxone and azithromycin; the last remaining empirical first-line therapy for gonorrhoea, are reported. However, ...
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(University of Pretoria, 2023-11-03)Vulvovaginal candidiasis (VVC) is a common condition in women of childbearing age worldwide and usually presents as vaginal discharge syndrome (VDS). Other important causes of VDS are bacterial vaginosis (BV) and sexually ...
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(University of Pretoria, 2023-11)Antimicrobial resistance (AMR) due to Enterobacterales is a worldwide public health threat. The continuous emergence of multidrug resistant (MDR) bacteria in developing countries with poor sanitation programmes, inactive ...
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(University of Pretoria, 2023-12)Globally, antimicrobial resistance (AMR) in foodborne pathogenic bacteria of the family Enterobacteriaceae has continued to rise. There is an increase in public health concerns about the spread of multi-drug resistant (MDR) ...
Now showing items 1-11 of 11