Browsing Medical Microbiology by Type "Article"

Now showing items 1-20 of 255

A 10-year cohort analysis of routine paediatric ART data in a rural South African setting

Lilian, R.P.; Mutasa, B.; Railton, J.; Mongwe, W.; McIntyre, J.A.; Struthers, H.E.; Peters, Remco P.H. (Cambridge University Press, 2017-01)

South Africa’s paediatric antiretroviral therapy (ART) programme is managed using a monitoring and evaluation tool known as TIER.Net. This electronic system has several advantages over paper-based systems, allowing ...
[18F]FDG PET and CT findings at therapy completion of pulmonary tuberculosis: comparison between HIV-positive and HIV-negative patients and impact on treatment response assessment

Ismaila, Aisha; Lawal, Ismaheel Opeyemi; Popoola, Gbenga O.; Mathebula, Matsontso; Moagi, Ingrid; Mokoala, Kgomotso M.G.; Honest, Ndlovu; Moeketsi, Nontando; Nchabeleng, Maphoshane; Hikuam, Chris; Hatherill, Mark; Fourie, P.B. (Petrus Bernardus); Sathekge, Mike Machaba (Springer, 2024)

BACKGROUND : [18F]FDG-PET/CT is a sensitive non-invasive tool for assessing treatment response in patients with pulmonary tuberculosis. The data on the performance of [18F]FDG-PET/CT for response assessment among patients ...
Acceptability and feasibility of integrating point-of-care diagnostic testing of sexually transmitted infections into a South African antenatal care program for HIV-infected pregnant women

Morikawa, E.; Mudau, M.; Olivier, D.; De Vos, L.; Davey, Dvora L. Joseph; Price, C.; McIntyre, J.A.; Peters, Remco P.H.; Klausner, J.D.; Medina-Marino, A. (Hindawi, 2018-05-09)

BACKGROUND : Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) infections may increase the risk of vertical transmission of the human immunodeficiency virus (HIV). In resource-limited ...
Acinetobacter baumannii : epidemiological and beta-lactamase data from two tertiary academic hospitals in Tshwane, South Africa

Lowe, Michelle; Ehlers, Marthie Magdaleen; Ismail, Farzana; Peirano, Gisele; Becker, Piet J.; Pitout, Johann D.D.; Kock, Marleen M. (Frontiers Media, 2018-06-12)

Acinetobacter baumannii is an opportunistic pathogen that is increasingly responsible for hospital-acquired infections. The increasing prevalence of carbapenem resistant A. baumannii has left clinicians with limited ...
Acinetobacter baumannii complex, national laboratory-based surveillance in South Africa, 2017 to 2019

Perovic, Olga; Duse, Adrian; Chibabhai, Vindana; Black, Marianne; Said, Mohamed; Prentice, Elizabeth; Wadula, Jeannette; Mahabeer, Yesholata; Han, Swe Swe; Mogokotleng, Ruth; Strasheim, Wilhelmina; Lowe, Michelle; Jallow, Sabelle; Ismail, Husna (Public Library of Science, 2022-08-04)

OBJECTIVE : We aimed to provide an analysis of A. baumannii complex (ABC) isolated from blood cultures in South Africa. MATERIALS AND METHODS : ABC surveillance was conducted from 1 April 2017 to 30 September 2019 at ...
Addressing missed visits to improve retention of young South African women in clinical trials

Ahmed, Khatija; Malahleha, Mookho; Mbatsane, Thulisile E.; Thindisa, Dineo; Bailey, Veronique C.; Seocharan, Ishen; Dilraj, Athmanundh (Academy of Science of South Africa, 2023-07)

In clinical trials, a vital protocol requirement for participants is adherence to scheduled visits. A substantial number of missed visits and the resultant missing data could affect generalisability of the findings ...
Adjunctive host-directed therapies for pulmonary tuberculosis : a prospective, open-label, phase 2, randomised controlled trial

Wallis, Robert S.; Ginindza, Sibuse; Beattie, Trevor; Arjun, Nishanee; Sebe, Modulakgotla; Likoti, Morongwe; Edward, Vinodh A.; Rassool, Mohammed; Ahmed, Khatija; Fielding, Katherine; Ahidjo, Bintou A.; Vangu, Mboyo D.T.; Churchyard, Gavin (Elsevier, 2021-08)

BACKGROUND : Current tuberculosis treatments leave patients with clinically significant lung injury and increased all-cause mortality post-cure. Adjunctive host-directed therapies could protect the lungs, improve long-term ...
Adult gonorrhea, chlamydia and syphilis prevalence, incidence, treatment and syndromic case reporting in South Africa : estimates using the Spectrum-STI model, 1990-2017

Kularatne, Ranmini S.; Niit, Ronelle; Rowley, Jane; Kufa-Chakezha, Tendesayi; Peters, Remco P.H.; Taylor, Melanie M.; Johnson, Leigh F.; Korenromp, Eline L. (Public Library of Science, 2018-10-15)

OBJECTIVES : To estimate trends in prevalence and incidence of syphilis, gonorrhea and chlamydia in adult men and women in South Africa. METHODS : The Spectrum-STI tool estimated trends in prevalence and incidence of ...
Analytical performance of the Roche Lightcycler® Mycobacterium Detection Kit for the diagnosis of clinically important mycobacterial species

Omar, Shaheed Vally; Roth, Andreas; Ismail, Nazir Ahmed; Erasmus, Linda; Ehlers, Marthie Magdaleen; Kock, Marleen M.; Paulse, Nuraan; Said, H.M. (Halima Mohammed); Hoosen, Anwar Ahmed; Reischl, Udo (Public Library of Science, 2011-09-22)

BACKGROUND: The LightCyclerH Mycobacterium Detection Kit based on real-time PCR technology for the detection of Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium kansasii was recently developed. This study ...
Anterior chamber paracentesis to improve diagnosis and treatment of infectious uveitis in South Africa

Schaftenaar, E.; Lecuona, K.A.; Baarsma, G.S.; Meenken, C.; Verjans, G.M.G.M.; McIntyre, J.A.; Peters, Remco P.H. (Health and Medical Publishing Group, 2015-08)

Infectious uveitis is a significant cause of blindness in South Africa, especially among HIV-infected individuals. The visual outcome of uveitis depends on early clinical and laboratory diagnosis to guide therapeutic ...
Antifungal susceptibility profile of yeast isolates from sterile sites at a tertiary hospital in South Africa

Makhado, Ndivhuho Agnes; Ismail, Farzana; Dangor, Yusuf; Chephe, Tlou J.H.; Hoosen, Anwar Ahmed; Nchabeleng, Maphoshane (MedPharm Publications, 2014)

Invasive infections caused by yeasts are associated with high mortality and morbidity, and resistance to antifungal agents is increasing. Candida spp. has emerged as the leading cause of systemic nosocomial fungal infections. ...
Antimicrobial resistance in Neisseria gonorrhoeae and Mycoplasma genitalium isolates from the private healthcare sector in South Africa : a pilot study

Maduna, Liteboho Daniel; Peters, Remco P.H.; Kingsburgh, C.; Strydom, K.A.; Kock, Marleen M. (SA MEDICAL ASSOC, 2021-10)

BACKGROUND. Reports have emerged globally of antimicrobial resistance (AMR) in Neisseria gonorrhoeae and Mycoplasma genitalium infections. In South Africa (SA), there are substantial differences between private and public ...
Antimicrobial resistance patterns of Acinetobacter baumannii and Klebsiella pneumoniae isolated from dogs presented at a veterinary academic hospital in South Africa

Sebola, Dikeledi Carol; Oguttu, James W.; Kock, Marleen M.; Qekwana, Daniel Nenene (Veterinary World, 2023-09-17)

BACKGROUND : Acinetobacter baumannii and Klebsiella pneumoniae are opportunistic bacterial pathogens responsible for hospital-acquired infections in veterinary medicine. Infection with these bacteria always requires urgent ...
Antimicrobial susceptibility and serotype distribution of Streptococcus agalactiae rectovaginal colonising isolates from pregnant women at a tertiary hospital in Pretoria, South Africa : an observational descriptive study

Said, Mohamed; Dangor, Yusuf; Mbelle, Nontombi Marylucy; Madhi, S.A.; Kwatra, G.; Ismail, F. (Health and Medical Publishing Group, 2020-09)

BACKGROUND. Streptococcus agalactiae or group B streptococcus (GBS) is a significant cause of neonatal sepsis. Intrapartum antibiotic prophylaxis is recommended for pregnant women identified to be rectovaginally colonised ...
Antimicrobial susceptibility patterns of gonococcal isolates in Pretoria, South Africa, over a 20-year period (1984-2004)

Dangor, Yusuf; De Jongh, M.; Adam, Anvir; Hoosen, Anwar Ahmed (Federation of Infectious Diseases Societies of South Africa, 2010)

This paper reviews the susceptibility profiles of Neisseria gonorrhoeae over a 20-year period in the Pretoria region. Endourethral specimens were collected from adult men with symptoms of urethritis attending primary ...
Antimicrobial susceptibility patterns of selected bacteraemic isolates from South African public sector hospitals, 2010

Bamford, Colleen; Bonorchis, Kim; Ryan, Anthea; Simpson, John; Elliott, Eugenne; Hoffmann, Rena; Naicker, Preneshni; Ismail, Nazir Ahmed; Mbelle, Nontombi Marylucy; Nchabeleng, Maphoshane; Nana, Trusha; Sriruttan, Charlotte; Seetharam, Sharona; Wadula, Jeannette (Federation of Infectious Diseases Societies of South Africa, 2011)

We report on antimicrobial susceptibility surveillance data for six key bloodstream pathogens (Escherichia coli, Klebsiella pneumoniae, Enterobacter spp., Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus ...
Antimicrobial susceptibility patterns of selected invasive pathogens from public sector hospitals in South Africa, 2007

Bamford, C.; Badenhorst, L.; Duse, A.G.; Hoosen, Anwar Ahmed; Nchabeleng, Maphoshane; Oliver, S.; Perovic, Olga; Sein, P.P.; Simpson, J.; Wadula, Jeannette; Wasserman, E. (Federation of Infectious Diseases Societies of South Africa, 2009)

Retrospective antibiotic surveillance data of selected invasive pathogens isolated from blood and cerebrospinal fluid at public sector hospitals in South Africa in 2007 are presented. Antimicrobial susceptibilities were ...
Antimicrobial susceptibility patterns of Ureaplasma species and Mycoplasma hominis in pregnant women

Redelinghuys, Mathys J.; Ehlers, Marthie Magdaleen; Dreyer, Andries W.; Lombaard, H.A.D.T. (Hennie); Kock, Marleen M. (BioMed Central, 2014-03)

BACKGROUND : Genital mycoplasmas colonise up to 80% of sexually mature women and may invade the amniotic cavity during pregnancy and cause complications. Tetracyclines and fluoroquinolones are contraindicated in pregnancy ...
Antimicrobial susceptibility profile of Neisseria gonorrhoeae from patients attending a medical laboratory, Institut Pasteur de Madagascar between 2014 and 2020 : phenotypical and genomic characterisation in a subset of Neisseria gonorrhoeae isolates

Rafetrarivony, Lala Fanomezantsoa; Rabenandrasana, Mamitina Alain Noah; Hariniaina, Elisoa Ratsima; Randrianirina, Frederique; Smith, Anthony Marius; Crucitti, Tania (BMJ Publishing Group, 2024-02)

OBJECTIVES : Antimicrobial-resistant Neisseria gonorrhoeae (NG) is a concern. Little is known about antimicrobial susceptibility profiles and associated genetic resistance mechanisms of NG in Madagascar. We report ...
Antiretroviral therapy, sexually transmitted infections, and adverse pregnancy outcomes in South Africa

Peters, Remco P.H.; Davey, Dvora L. Joseph; Bekker, Linda-Gail; Myer, Landon; Medina-Marino, Andrew; Klausner, Jeffrey D. (Oxford University Press, 2021-08)

We read with interest the article by Theron et al. on their post hoc analysis of the Promoting Maternal and Infant Survival Everywhere (PROMISE) 1077BF/1077FF trials. They found an increased incidence of low birth-weight ...

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