• The use of in vitro bioassays and chemical screening to assess the impact of a minimally processed vegetable facility on wastewater quality 

  Aneck-Hahn, Natalie Hildegard; Van Zijl, Magdalena Catherina; Quinn, Laura; Swiegelaar, Caitlin; Nhlapo, N.S. (Nontete Suzan); De Bruin, Willeke; Korsten, Lise (Frontiers Media, 2024-09)

  Fruit- and vegetable-processing facilities may contaminate wastewater via contaminants found in the produce and disinfecting chemicals used. These contaminants may include agrochemicals, pesticides, and disinfectants ...
• The impact of pharmacotherapy on sexual function in female patients being treated for idiopathic overactive bladder : a systematic review 

  Evans, Christopher Neal Bruce; Badenhorst, Anja; Van Wijk, Frans Jacob (BMC, 2024-05)

  BACKGROUND: Overactive bladder (OAB) is a condition defined by urgency with or without incontinence which disproportionately affects female patients and has a negative impact on sexual enjoyment and avoidance behaviour. ...
• Assessment of neuropathic pain management knowledge, attitudes, and practices among urology trainees and consultants in prostate cancer care : a survey-based study 

  Sinkila, Ongeziwe; Matjomane, N.; Cronje, Tanita; Mathabe, Kgomotso (Springer, 2024-04)

  BACKGROUND: Effective neuropathic pain management is crucial in improving the quality of life for patients with prostate cancer. There is an abundance of research about cancer pain and guidelines that have been developed ...
• Quality and safety of South African hand sanitisers during the COVID-19 pandemic 

  De Bruin, Willeke; Van Zijl, Magdalena Catherina; Aneck-Hahn, Natalie H.; Korsten, Lise (Taylor and Francis, 2024)

  Health agencies recommend using hand sanitisers as protection against the coronavirus. Thus far, the emphasis on hand sanitiser studies is limited to an analysis of disinfectant content only. This study aims to provide an ...
• In silico bioinformatics analysis on the role of long non-coding RNAs as drivers and gatekeepers of androgen-independent prostate cancer using LNCaP and PC-3 cells 

  Mbeje, Mandisa; Kandhavelu, Jeyalakshmi; Penny, Clement; Kgoebane-Maseko, Minah; Dlamini, Zodwa; Marima, Rahaba (MDPI, 2023-09-01)

  Prostate cancer (PCa) is the leading cancer in men globally. The association between PCa and long non-coding RNAs (lncRNAs) has been reported. Aberrantly expressed lncRNAs have been documented in each of the cancer ...
• Renal papillary necrosis (RPN) in an African population : disease patterns, relevant pathways, and management 

  Gaudji, Guy Roger; Bida, M.; Conradie, Marius; Damane, Botle Precious; Bester, Megan (MDPI, 2023-01)

  Renal papillary necrosis (RPN) is characterized by coagulative necrosis of the renal medullary pyramids and papillae. Multiple conditions and toxins are associated with RPN. Several RPN risk factors, or POSTCARDS, have ...
• Standards in semen examination : publishing reproducible and reliable data based on high-quality methodology 

  Bjorndahl, Lars; Barratt, Christopher L.R.; Mortimer, David; Agarwal, Ashok; Aitken, Robert J.; Alvarez, Juan G.; Aneck-Hahn, Natalie Hildegard; Arver, Stefan; Baldi, Elisabetta; Bassas, Lluis; Boitrelle, Florence; Bornman, Maria S. (Riana); Carrell, Douglas T.; Castilla, Jose A.; Cerezo Parra; Parra, Gerardo Cerezo; Check, Jerome H.; Cuasnicu, Patricia S.; Darney, Sally Perreault; De Jager, Christiaan; De Jonge, Christopher J.; Drevet, Joel R.; Drobnis, Erma Z.; Du Plessis, Stefan S.; Eisenberg, Michael L.; Esteves, Sandro C.; Evgeni, Evangelini A.; Ferlin, Alberto; Garrido, Nicolas; Giwercman, Aleksander; Goovaerts, Ilse G.F.; Haugen, Trine B.; Henkel, Ralf; Henningsohn, Lars; Hofmann, Marie-Claude; Hotaling, James M.; Jedrzejczak, Piotr; Jouannet, Pierre; Jorgensen, Niels; Kirkman Brown, Jackson C.; Krausz, Csilla; Kurpisz, Maciej; Kvist, Ulrik; Lamb, Dolores J.; Levine, Hagai; Loveland, Kate L.; McLachlan, Robert, I.; Mahran, Ali; Maree, Liana; Da Silva, Sarah Martins; Mbizvo, Michael T.; Meinhardt, Andreas; Menkveld, Roelof; Mortimer, Sharon T.; Moskovtsev, Sergey; Muller, Charles H.; Jose Munuce, Maria; Muratori, Monica; Niederberger, Craig; O'Flaherty, Cristian; Oliva, Rafael; Ombelet, Willem; Pacey, Allan A.; Palladino, Michael A.; Ramasamy, Ranjith; Ramos, Liliana; Rives, Nathalie; Roldan, Eduardo Rs; Rothmann, Susan; Sakkas, Denny; Salonia, Andrea; Sanchez-Pozo, Maria Cristina; Sapiro, Rosanna; Schlatt, Stefan; Schlegel, Peter N.; Schuppe, Hans-Christian; Shah, Rupin; Skakkebaek, Niels E.; Teerds, Katja; Toskin, Igor; Tournaye, Herman; Turek, Paul J.; Van der Horst, Gerhard; Vazquez-Levin, Monica; Wang, Christina; Wetzels, Alex; Zeginiadou, Theodosia; Zini, Armand (Oxford University Press, 2022-10)

  Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen ...
• AI and precision oncology in clinical cancer genomics : from prevention to targeted cancer therapies-an outcomes based patient care 

  Dlamini, Zodwa; Skepu, Amanda; Kim, Namkug; Mkhabele, Mahlori; Khanyile, Richard; Molefi, Thulo; Mbatha, Sikhumbuzo; Setlai, Botle; Mulaudzi, Thanyani Victor; Mabongo, Mzubanzi; Bida, Nndweleni Meshack; Kgoebane-Maseko, Minah; Mathabe, Kgomotso; Lockhat, Zarina I.; Kgokolo, C.M.; Chauke-Malinga, Nkhensani; Ramagaga, Serwalo; Hull, Rodney (Elsevier, 2022)

  Precision medicine is the personalization of medicine to suit a specific group of people or even an individual patient, based on genetic or molecular profiling. This can be done using genomic, transcriptomic, epigenomic ...
• Influence of the microbiome metagenomics and epigenomics on gastric cancer 

  Mathebela, Precious; Damane, Botle Precious; Mulaudzi, Thanyani Victor; Mkhize-Khwitshana, Zilungile Lynette; Gaudji, Guy Roger; Dlamini, Zodwa (MDPI, 2022-11)

  Gastric cancer (GC) is one of the major causes of cancer deaths worldwide. The disease is seldomly detected early and this limits treatment options. Because of its heterogeneous and complex nature, the disease remains ...
• The role of effect-based methods to address water quality monitoring in South Africa : a developing country’s struggle 

  Kruger, Annika; Pieters, Rialet; Horn, Suranie; Van Zijl, Catherina; Aneck-Hahn, Natalie Hildegard (Springer, 2022-12)

  Water is an important resource, and it is a worldwide struggle to provide water of good quality to the whole population. Despite good governing laws and guidelines set in place to help protect the water resources and ensure ...
• Role of precision oncology in type II endometrial and prostate cancers in the African population : global cancer genomics disparities 

  Marima, Rahaba; Hull, Rodney; Mbeje, Mandisa Pearl; Molefi, Thulo; Mathabe, Kgomotso; Elbagory, Abdulrahman M.; Demetriou, Demetra Danielle; Dlamini, Zodwa (MDPI, 2022-01-06)

  Precision oncology can be defined as molecular profiling of tumors to identify targetable alterations. Emerging research reports the high mortality rates associated with type II endometrial cancer in black women and with ...
• Immune checkpoints, inhibitors and radionuclides in prostate cancer : promising combinatorial therapy approach 

  Kgatle, Mankgopo; Boshomane, Tebatso M.G.; Lawal, Ismaheel Opeyemi; Mokoala, Kgomotso M.G.; Mokgoro, Neo P.; Lourens, Nico; Kairemo, Kalevo; Zeevaart, Jan Rijn; Vorster, Mariza; Sathekge, Mike Machaba (MDPI Publishing, 2021-04-15)

  Emerging research demonstrates that co-inhibitory immune checkpoints (ICs) remain the most promising immunotherapy targets in various malignancies. Nonetheless, ICIs have offered insignificant clinical benefits in the ...
• Clinician’s guide to perineal and obstetric anal sphincter injury 

  Paterson, Frances; Retief, Francois; Swart, Paul; Abdool, Zeelha (In House Publications, 2020-07)

  Perineal trauma is a common consequence of vaginal childbirth. This may be spontaneous or an iatrogenic event following an episiotomy, or a combination of the two. One UK study states that up to 85% of women experience ...
• Many voices in a choir: tumor-induced neurogenesis and neuronal driven alternative splicing sound like suspects in tumor growth and dissemination 

  Dlamini, Zodwa; Mathabe, Kgomotso; Padayachy, Llewellyn; Marima, Rahaba; Evangelou, George; Syrigos, Konstantinos N.; Bianchi, Arianna; Lolas, Georgios; Hull, Rodney (MDPI, 2021-05)

  During development, as tissues expand and grow, they require circulatory, lymphatic, and nervous system expansion for proper function and support. Similarly, as tumors arise and develop, they also require the expansion ...
• Prostate cancer racial, socioeconomic, geographic disparities : targeting the genomic landscape and splicing events in search for diagnostic, prognostic and therapeutic targets 

  Marima, Rahaba; Hull, Rodney; Mathabe, Kgomotso; Setlai, Botle Precious; Batra, Jyotsna; Sartor, Oliver; Mehrotra, Ravi; Dlamini, Zodwa (e-Century Publishing, 2021-04)

  Prostate cancer (PCa) is one of the leading causes of deaths in men globally. This is a heterogeneous and complex disease that urgently warrants further insight into its pathology. Developed countries have thus far the ...
• Veterinary growth promoters in cattle feedlot runoff : estrogenic activity and potential effects on the rat male reproductive system 

  Patrick, Sean Mark; Aneck-Hahn, Natalie Hildegard; Van Wyk, Susan; Van Zijl, Magdalena Catherina; Huma, Mampedi; De Jager, Christiaan (Springer, 2020-04)

  The contribution of veterinary growth promoters (VGP) to the environmental burden of endocrine-disrupting chemicals (EDCs) is largely unknown. At cattle feedlots, the excrement of cattle may contain VGPs, which can contaminate ...
• Endocrine-disrupting activity of the fungicide mancozeb used in the Vhembe District of South Africa 

  Seshoka, M.F.; Van Zijl, Magdalena Catherina; Aneck-Hahn, Natalie Hildegard; Barnhoorn, I.E.J. (NISC (Pty) Ltd and Informa UK Limited (trading as Taylor & Francis Group), 2021)

  Many chemicals released into the environment are believed to disrupt normal endocrine functions in humans and animals. A major group of endocrine disrupting chemicals (EDCs) that could be responsible for reproductive defects ...
• A qualitative exploration of South African men’s perceived effects of androgen deprivation therapy (ADT) as a treatment for advanced prostate cancer 

  Gray, Peter B.; Meintjes, F.; Moshokwa, Evelyn; Mathabe, Kgomotso (Taylor and Francis, 2020)

  OBJECTIVE : We undertake qualitative research with men treated in a Pretoria, South Africa Oncology clinic to address men’s self-reported experiences on androgen deprivation therapy (ADT). METHODS : Analyses rely upon 22 ...
• Removal of pharmaceutical' estrogenic activity of sequencing batch reactor effluents assessed in the T47D-KBluc report 

  Kasonga, Teddy Kabeya; Coetzee, Martie A.A.; Van Zijl, Magdalena Catherina; Momba, Maggy Ndombo Benteke (Elsevier, 2019-06)

  Various water treatment processes may be ineffective to remove pharmaceutical compounds (PhCs) and their by-products, leading to endocrine-disruptive activity that might be detrimental to wildlife and human health. This ...
• Data on UPLC/MS method validation for the biodegradation of pharmaceuticals and intermediates by a fungal consortium and on T47DK-Bluc reporter gene assay to assess the reduction of their estrogenic activity 

  Kasonga, Teddy Kabeya; Coetzee, Martie A.A.; Van Zijl, Magdalena Catherina; Momba, Maggy Ndombo Benteke (Elsevier, 2019-08)

  In term of pharmaceutical and their intermediate compounds analysis, UPLC/MS method is a valuable equipment to achieve better confirmation on their biodegradation by fungi. The T47DKBluc reporter gene assay is an ...

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