Browsing Medical Virology by Issue Date

Now showing items 1-20 of 452

Detection of EBV DNA in oral squamous cell carcinomas in a black African population sample

Janse van Rensburg, Estrelita; Engelbrecht, Susan; Van Heerden, Willem Francois Petrus; Raubenheimer, E.J.; Schoub, Barry D. (International Institute of Anticancer Research, 1995-05)

The purpose of this study was to determine the presence of Epstein-Barr virus (EBV) DNA in oral squamous cell carcinoma (OSCC) patients from a black African population. Formalin fixed paraffin embedded blocks of OSCC of ...
Prevalence of EBV in oral squamous cell carcinomas in young patients

Van Heerden, Willem Francois Petrus; Janse van Rensburg, Estrelita; Engelbrecht, Susan; Raubenheimer, E.J. (International Institute of Anticancer Research, 1995-09)

BACKGROUND: Recent studies reported a difference in the age distribution of oral squamous cell carcinoma (OSCC) between black and white South Africans with OSCC more prevalent in black patients under the age of 50 compared ...
Identification of env subtypes in fourteen HIV type 1 isolates from South Africa

Engelbrecht, Susan; Laten, Janetta D.; Smith, Tracey-Lee; Janse van Rensburg, Estrelita (Mary Ann Liebert, 1995-10)

All subtypes of HIV-1 have been identified in Africa. The envelope glycoprotein of the HIV-1 is the most variable region of the virus, with the third variable region, including the V3 loop, a major target of vaccine research. ...
Human papillomavirus DNA in oral squamous cell carcinomas from an African population sample

Janse van Rensburg, Estrelita; Engelbrecht, Susan; Van Heerden, Willem Francois Petrus; Raubenheimer, E.J.; Schoub, Barry D. (International Institute of Anticancer Research, 1996-03)

BACKGROUND: The incidence of oral squamous cell carcinoma (OSCC) is on the increase in developing countries. MATERIALS AND METHODS: Formalin fixed paraffin embedded blocks of OSCCs from a black South African population ...
Simian immunodeficiency viruses (SIVs) from eastern and southern Africa : detection of a SIVagm variant from a chacma baboon

Janse van Rensburg, Estrelita; Engelbrecht, Susan; Mwenda, Jason M.; Laten, Janetta D.; Robson, Brenda A.; Stander, Tania; Chege, Gerald K. (American Society for Microbiology, 1998)

Simian immunodeficiency viruses (SIVs) have been shown to infect many old world African primate species. Thus far, no work has been published on southern African primates. In this study we investigated the genetic diversity ...
Correlation between p53 gene mutation, p53 protein labeling and PCNA expression in oral squamous cell carcinomas

Van Heerden, Willem Francois Petrus; Janse van Rensburg, Estrelita; Hemmer, J.; Raubenheimer, E.J.; Engelbrecht, Susan (International Institute of Anticancer Research, 1998-01)

The prevalence of oral squamous cell carcinoma (OSCC) among the black community in South Africa is unacceptably high. The association between p53 protein, and PCNA overexpression and the presence of p53 gene mutations was ...
Variation in HIV type 1 V3 region env sequences from Mozambique

Engelbrecht, Susan; Koulinska, Irene; Smith, Tracey-Lee; Baretto, J.; Janse van Rensburg, Estrelita (Mary Ann Liebert, 1998-06-10)

No abstract available.
HIV type 1 V3 region subtyping in KwaZulu-Natal, a high-seroprevalence South African region

Moodley, D.; Smith, Tracey-Lee; Janse van Rensburg, Estrelita; Moodley, J.; Engelbrecht, Susan (Mary Ann Liebert, 1998-07-20)

No abstract available.
HIV Type 1 V3 domain serotyping and genotyping in Gauteng, Mpumalanga, KwaZulu-Natal and Western Cape provinces of South Africa

Clay, Cornelius G.; Engelbrecht, Susan; Smith, Tracey-Lee; Kasper, P.; Faatz, E.; Zeier, Michelle D.; Moodley, D.; Janse van Rensburg, Estrelita (Mary Ann Liebert, 1999)

More than 20.8 million people are living with HIV/AIDS in sub-Saharan Africa, with southern Africa the worst affected area and accounting for one of the fastest growing AIDS epidemics worldwide. Samples from 81 patients, ...
Subtyping of human t cell lymphotropic virus type I from tropical spastic paraparesis/HTLV-associated myelopathy patients in Mozambique

Engelbrecht, Susan; Koulinska, Irene; Smith, Tracey-Lee; Robson, Brenda A.; Barreto, Jorge; Janse van Rensburg, Estrelita (Mary Ann Liebert, 1999-01)
Absence of human herpesvirus-8 DNA in Kaposi's sarcoma following postmastectomy lymphoedema

Du Plessis, D.G.; Schneider, Johann W.; Treurnicht, Florette K.; Engelbrecht, Susan; Janse van Rensburg, Estrelita (Blackwell, 2000-05)

No abstract available
Characterization and phylogenetic analysis of South African HIV-1 subtype C accessory genes

Scriba, Thomas Jens; Treurnicht, Florette K.; Zeier, Michelle D.; Engelbrecht, Susan; Janse van Rensburg, Estrelita (Mary Ann Liebert, 2001-05)

To acquire new knowledge about the genetic diversity and potential impact on vaccine strategies of HIV-1 subtype C in South Africa, we have characterized the vif, vpr, and vpu genes of 15 isolates. Phylogenetic analysis ...
Genetic analysis of the complete gag and env genes of HIV type 1 subtype C primary isolates from South Africa

Engelbrecht, Susan; De Villiers, Tania; Sampson, Candice C.; Zur Megede, Jan; Barnett, Susan W.; Janse van Rensburg, Estrelita (Mary Ann Liebert, 2001-11)

South Africa has one of the fastest growing HIV-1 epidemics, with an estimated 4.7 million people infected. To better understand the genetic diversity of this epidemic and its potential impact on vaccine development, we ...
Characterisation of the South African HIV-1 subtype C complete 5’ LTR, nef and regulatory genes

Scriba, Thomas Jens; De Villiers, Tania; Treurnicht, Florette K.; Zur Megede, Jan; Barnett, Susan W.; Engelbrecht, Susan; Janse van Rensburg, Estrelita (Mary Ann Liebert, 2002-01)

Human immunodeficiency virus type 1 (HIV-1) subtype C has become the major etiological agent in the global and especially African epidemic. To gain better understanding of the genetic diversity and rapid transmission of ...
HHV-8 subtypes in South Africa : identification of a case suggesting a novel B variant

Treurnicht, Florette K.; Engelbrecht, Susan; Taylor, Maureen B.; Schneider, Johann W.; Janse van Rensburg, Estrelita (Wiley, 2002-02)

Human herpesvirus 8 (HHV-8) has been identified as the causative agent for all forms of Kaposi's sarcoma and is also associated with the development of body cavity-based B-cell lymphomas and multicentric Castleman's disease. ...
Novel evolutionary analyses of full-length HIV type 1 subtype C molecular clones from Cape Town South Africa

Cassol, Sharon; Zur Megede, Jan; Engelbrecht, Susan; De Oliveira, Tulio; Scriba, Thomas Jens; Janse van Rensburg, Estrelita; Barnett, Susan W. (Mary Ann Liebert, 2002-11)

Understanding the origin, distribution, and evolving dominance of HIV-1 subtype C strains is an important component in the design and evaluation of a globally effective AIDS vaccine. To better understand subtype C viruses, ...
Change in co-receptor usage of current South African HIV-1 subtype C primary isolates

Janse van Rensburg, Estrelita; Smith, Tracey-Lee; Zeier, Michelle D.; Robson, Brenda A.; Sampson, Candice C.; Treurnicht, Florette K.; Engelbrecht, Susan (Lippincott Williams and Wilkins, 2002-12-06)
Molecular characteristics of HIV-1 Subtype C viruses from KwaZulu-Natal, South Africa: implications for vaccine and antiretroviral control strategies

Cassol, Sharon; Gordon, Michelle; De Oliveira, Tulio; Bishop, Karen; Coovadia, H.M.; Madurai, L.; Engelbrecht, Susan; Janse van Rensburg, Estrelita; Mosam, A.; Smith, A. (American Society for Microbiology, 2003-02)

The KwaZulu-Natal region of South Africa is experiencing an explosive outbreak of Human Immunodeficiency Virus Type 1 (HIV-1) Subtype C infections. Understanding the genetic diversity of C viruses and the biological ...
Rhinovirus induction of the CXC chemokine epithelial-neutrophil activating peptide-78 in bronchial epithelium

Donninger, Howard; Glashoff, Richard H.; Haitchi, Hans-Michael; Syce, James A.; Ghildyal, Reena; Janse van Rensburg, Estrelita; Bardin, Philip G. (University of Chicago Press, 2003-06-01)

Epithelial-neutrophil activating peptide-78 (ENA-78) induces neutrophil migration, an early response to viral infection. Rhinovirus serotype 16 (RV16) was used to infect primary bronchial epithelial cells and a cell line ...
Variability at Human Immunodeficiency Virus Type 1 Subtype C Protease Cleavage Sites : an indication of viral fitness

Cassol, Sharon; De Oliveira, Tulio; Engelbrecht, Susan; Janse van Rensburg, Estrelita; Gordon, Michelle; Bishop, Karen; Zur Megede, Jan; Barnett, Susan W. (American Society for Microbiology, 2003-09)

Naturally occurring polymorphisms in the protease of human immunodeficiency virus type 1 (HIV-1)subtype C would be expected to lead to adaptive (compensatory) changes in protease cleavage sites. To test this hypothesis, ...

Now showing items 1-20 of 452

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