Cervical cancer and human papillomavirus : South African guidelines for screening and testing

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dc.contributor.author Botha, Hennie
dc.contributor.author Cooreman, Bruno
dc.contributor.author Dreyer, Greta
dc.contributor.author Lindeque, B. Gerhard
dc.contributor.author Mouton, Arrie
dc.contributor.author Guidozzi, Franco
dc.contributor.author Koller, Tony
dc.contributor.author Smith, Trudy
dc.contributor.author Hoosen, Anwar Ahmed
dc.contributor.author Marcus, Louis
dc.contributor.author Moodley, Manivasan
dc.contributor.author Soeters, Robbie
dc.date.accessioned 2011-06-13T09:01:03Z
dc.date.available 2011-06-13T09:01:03Z
dc.date.issued 2010
dc.description.abstract Cervical carcinoma is still the most common cancer of women on the African continent. Mortality remains high – worldwide at 50% – mainly because of late presentation, advanced stage of disease and absence of a functioning screening process. The aetiological link between human papillomavirus (HPV) infection and cervical cancer has been well established and a number of high-risk HPV genotypes have been identified. HPV infection is the most common sexually transmitted infection (STI) in the world today – up to 80% of sexually active females will harbour HPV at some point in their lives. The majority of women will experience natural elimination of HPV infection because of an intact immune system. Persistent infection with a high risk type HPV puts women at high risk to develop precursors of cervical cancer or carcinoma itself. As part of a public health response to this serious problem, several HPV vaccines are under development. Use of vaccines still poses unanswered questions in many respects. en_US
dc.identifier.citation Botha, H, Cooreman, B, Dreyer, G, Lindeque, G, Mouton, A, Guidozzi, F, Koller, T, Smith, T, Hoosen, A, Marcus, L, Moodley, M & Soeters, R 2010, 'Cervical cancer and human papillomavirus : South African guidelines for screening and testing', Southern African Journal of Gynaecological Oncology, vol. 2, no. 1, pp. 23-26. [http://www.sajgo.co.za/index.php/sajgo] en_US
dc.identifier.issn 2074-2835
dc.identifier.uri http://hdl.handle.net/2263/16803
dc.language.iso en en_US
dc.publisher Open Journals Systems en_US
dc.rights This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.5 South Africa License. en_US
dc.subject Cervical cancer en_US
dc.subject Human papillomavirus (HPV) en_US
dc.subject Sexually transmitted infection (STI) en_US
dc.title Cervical cancer and human papillomavirus : South African guidelines for screening and testing en_US
dc.type Article en_US


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