A biomimetic approach to the synthesis of a mycolic acid motif

Driver, Kathy (Cathryn Helena Stanford); Balogun, Mohammed Olusegun; Toschi, Gianna; Verschoor, J.A. (Jan Adrianus), 1953-; Baird, Mark S.; Pilcher, Lynne A.

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dc.contributor.author	Driver, Kathy (Cathryn Helena Stanford)
dc.contributor.author	Balogun, Mohammed Olusegun
dc.contributor.author	Toschi, Gianna
dc.contributor.author	Verschoor, J.A. (Jan Adrianus), 1953-
dc.contributor.author	Baird, Mark S.
dc.contributor.author	Pilcher, Lynne A.
dc.date.accessioned	2010-01-28T10:13:31Z
dc.date.available	2010-01-28T10:13:31Z
dc.date.issued	2010-02
dc.description.abstract	A new method for the stereoselective synthesis of the (R,R)-b-hydroxy-a-alkyl fatty acid fragment of mycolic acids, via an asymmetric anti-aldol reaction is reported. The ‘mycolic acid motif’ fragment was prepared in three steps and >98% ee.	en
dc.identifier.citation	Driver, C. H. S.; et al. A biomimetic approach to the synthesis of a mycolic motif, Tetrahedron Letters, vol. 51, no. 8, pp. 1185-1186 (2010), doi:10.1016/j.tetlet.2009.12.105	en
dc.identifier.isbn	0040-4039
dc.identifier.other	10.1016/j.tetlet.2009.12.105
dc.identifier.uri	http://hdl.handle.net/2263/12794
dc.language.iso	en	en
dc.publisher	Elsevier	en
dc.rights	Elsevier	en
dc.subject	Mycolic acid motif	en
dc.subject	Asymmetric anti-aldol reaction	en
dc.subject.lcsh	Tuberculosis	en
dc.subject.lcsh	Biomimetics	en
dc.title	A biomimetic approach to the synthesis of a mycolic acid motif	en
dc.type	Postprint Article	en