Abstract:
Large quantities of toxoid given to rabbits per os did not elicit a primary immune response. Toxin absorbed through the intestinal wall of guinea-pigs and toxoided produced an anamnestic response on injection into basically-immune rabbits, but had no effect on fully susceptible rabbits. By dosing sufficient toxin or toxoid per os to basically-immune rabbits anamnestic responses could be produced.
Description:
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