Carboxy-amidated AamAP1-lys has superior conformational flexibility and accelerated killing of gram-negative bacteria

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dc.contributor.author Van Wyk, Rosalind Jeanette
dc.contributor.author Serem, June Cheptoo
dc.contributor.author Oosthuizen, Carel B.
dc.contributor.author Semenya, Dorothy
dc.contributor.author Serian, Miruna
dc.contributor.author Lorenz, Christian D.
dc.contributor.author Mason, A. James
dc.contributor.author Bester, Megan Jean
dc.contributor.author Gaspar, Anabella Regina Marques
dc.date.accessioned 2025-03-07T13:15:37Z
dc.date.available 2025-03-07T13:15:37Z
dc.date.issued 2025-02
dc.description.abstract Please read abstract in the article. en_US
dc.description.department Anatomy en_US
dc.description.department Biochemistry, Genetics and Microbiology (BGM) en_US
dc.description.librarian hj2024 en_US
dc.description.sdg SDG-03:Good heatlh and well-being en_US
dc.description.sponsorship The South African Medical Research Council; the SA-UK Newton Fund Antibiotic Accelerator; the UK Materials and Molecular Modeling Hub for computational resources, which is partially funded by EPSRC and a BBSRC LIDo studentship. en_US
dc.description.uri https://pubs.acs.org/journal/bichaw?ref=breadcrumb en_US
dc.identifier.citation Van Wyk, R.J., Serem, J.C., Oosthuizen, C.B. et al. 2025, 'Carboxy-amidated AamAP1-lys has superior conformational flexibility and accelerated killing of gram-negative bacteria', Biochemistry, vol. 64, no. 4, pp. 841-859, doi : 10.1021/acs.biochem.4c00580. en_US
dc.identifier.issn 0006-2960 (print)
dc.identifier.issn 1520-4995 (online)
dc.identifier.other 10.1021/acs.biochem.4c00580
dc.identifier.uri http://hdl.handle.net/2263/101390
dc.language.iso en en_US
dc.publisher American Chemical Society en_US
dc.rights © 2025 The Authors. Published by American Chemical Society. This publication is licensed under CC-BY 4.0. en_US
dc.subject Bacteria en_US
dc.subject Biofilms en_US
dc.subject Membranes en_US
dc.subject Organic reactions en_US
dc.subject Peptides and proteins en_US
dc.subject Antimicrobial peptide (AMP) en_US
dc.subject C-terminal amidation en_US
dc.subject SDG-03: Good health and well-being en_US
dc.title Carboxy-amidated AamAP1-lys has superior conformational flexibility and accelerated killing of gram-negative bacteria en_US
dc.type Article en_US


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