Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine

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dc.contributor.author Mlingo, Tendai A.M.
dc.contributor.author Beeton-Kempen, Natasha
dc.contributor.author Nthangeni, M. Bethuel
dc.contributor.author Theron, Jacques
dc.contributor.author Mokoena, Nobalanda B.
dc.date.accessioned 2025-02-12T13:05:57Z
dc.date.available 2025-02-12T13:05:57Z
dc.date.issued 2024-06
dc.description DATA AVAILABILITY : The raw sequence data as well as assembled sequence data of the 15 serotypes were deposited in GenBank under BioProject number PRJNA718723. The accession numbers are summarised in Table 1. Detailed information on the sequencing data generated for each serotype such as nucleotide identity and the South African reference strain applied is available in Table S1 in figshare (https://doi.org/10.6084/m9.figshare.25611486 25611486). en_US
dc.description.abstract Bluetongue disease in endemic areas is predominantly controlled through vaccination with live-attenuated vaccines. Sequencing of the original master seed viruses used in the production of Onderstepoort Biological Products vaccine was conducted. Nucleotide identities of 82.97%–100% were obtained for all sequences when compared to South African reference strains. en_US
dc.description.department Biochemistry, Genetics and Microbiology (BGM) en_US
dc.description.librarian am2024 en_US
dc.description.sdg SDG-03:Good heatlh and well-being en_US
dc.description.sponsorship Onderstepoort Biological Products, the University of Pretoria (Faculty of Natural and Agricultural Sciences), and the Chemical Industries Education and Training Authority. en_US
dc.description.uri https://journals.asm.org/journal/mra en_US
dc.identifier.citation Mlingo, T.A.M., Beeton-Kempen, N., Nthangeni, M.B. et al. 2024, 'Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine', Microbiology Resource Announcements, vol. 13, no. 6, pp. 1-4. DOI: 10.1128/mra.00223-24. en_US
dc.identifier.issn 2576-098X
dc.identifier.other 10.1128/mra.00223-24
dc.identifier.uri http://hdl.handle.net/2263/100789
dc.language.iso en en_US
dc.publisher American Society for Microbiology en_US
dc.rights © 2024 Mlingo et al. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license. en_US
dc.subject Vaccines en_US
dc.subject Live-attenuated en_US
dc.subject Bluetongue virus en_US
dc.subject Bluetongue virus (BTV) en_US
dc.subject SDG-03: Good health and well-being en_US
dc.title Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine en_US
dc.type Article en_US


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