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Browsing by UP Author "Soma, Prashilla"
Now showing items 1-20 of 30
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Soma, Prashilla; Ueckermann, Veronica; Sasikumar, S.S. (Sunayana); Mashoeshoe, K.S. (Sam) (Elsevier, 2016-01)The diagnosis of porphyria remains challenging as the condition is characterized by a myriad of clinical and biochemical features. More importantly, an acute attack is associated with increased morbidity and mortality. ...
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Soma, Prashilla; Ellemdin, Shiraz (Clinics Cardiv, 2012-09)It is now clear that hepatopulmonary syndrome (HPS) may occur and contribute significantly to gas exchange abnormalities in the setting of other cardiopulmonary abnormalities. Since there is no gold-standard diagnostic ...
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Buys, A.V. (Antonia Vergina); Van Rooy, Mia-Jeanne; Soma, Prashilla; Van Papendorp, D.H. (Dirk Hermanus), 1949-; Lipinski, Boguslaw; Pretorius, Etheresia (BioMed Central, 2013-01-28)Red blood cells (RBCs) are highly deformable and possess a robust membrane that can withstand shear force. Previous research showed that in diabetic patients, there is a changed RBC ultrastructure, where these cells ...
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Olumuyiwa-Akeredolu, Oore-ofe O.; Soma, Prashilla; Buys, A.V. (Antonia Vergina); Debusho, Legesse Kassa; Pretorius, Etheresia (Elsevier, 2017-12)The inflammatory burden of the complex rheumatoid arthritis (RA) disease affects several organ-systems, including rheological properties of blood and its formed elements. Red blood cells (RBCs) are constantly exposed to ...
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Soma, Prashilla; Ellemdin, Shiraz (Medpharm Publications, 2009-05)Disseminated histoplasmosis can be the initial clue to the presence of AIDS. In HIV infected patients, histoplasmosis can present with unusual manifestations, without a positive exposure history or outside the typical ...
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Du Toit, Peet J.; Kruger, P.E. (Pieter Ernst); Tsotetsi, A.; Soma, Prashilla; Govender, Catherine; Henning, E.; Naicker, Lee-Anne; Grant, C.C. (Catharina Cornelia); Wood, Paola Silvia; Terblanche, E. (Africa Association for Health, Physical Education, Recreation, Sport and Dance, 2012-03)Research has shown that a strong correlation exists between vision and performance. In the sporting environment, it is believed that athletes perform better than non-athletes and males perform better than females. In this ...
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Soma, Prashilla; Ellemdin, Shiraz; Roche, Natalie J. (Elsevier, 2014-08)In March, 2013, a 37-year-old woman presented to the emergency department with a 6 month history of worsening dyspnoea, fatigue, insomnia, and generalised body pains. She had no cough or haemoptysis, was a non-smoker, and ...
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Soma, Prashilla; Kara, S. (Health and Medical Publishing Group, 2014-09)HIV is not indicated in the aetiology of Castleman’s disease. However, it impacts on the prevalence and natural history of this disease and signi cantly on the disease progression. Castleman’s disease is a uni- or ...
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Soma, Prashilla; Ellemdin, Shiraz; Mashoeshoe, K.S. (Sam) (Elsevier, 2013)Hematologic abnormalities feature commonly in patients with human immunodeficiency virus (HIV) infection. This includes anaemia and it occurs in 70 – 80% of patients. The causes of HIV-related anaemia are multifactorial. ...
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Adam, Lyla; Phulukdaree, Alisa; Soma, Prashilla (Elsevier, 2018-04)Azathioprine (AZA) is a well-known immunosuppressant used for many years for its ability to ensure long term disease remission in inflammatory bowel diseases (IBD) at an affordable cost to the public. However, the side ...
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Phasha, Marry-Ann Ntanyane; Soma, Prashilla; Bester, Janette; Pretorius, E.; Phulukdaree, Alisa (Elsevier, 2022-08)Factor XIII, a transglutaminase that plays a crucial role in clot formation, consists of subunits A and B. Single nucleotide polymorphisms in Factor XIII-A have been linked to thrombotic risk. In Type 2 Diabetes mellitus ...
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Soma, Prashilla; Swanepoel, A.C. (Albe Carina); Du Plooy, Jeanette Noel; Mqoco, T.V. (Thandi Vuyelwa); Pretorius, Etheresia (BioMed Central, 2016-03-31)BACKGROUND : The function of platelets have extended way beyond the horizon of haemostasis and thrombosis, and are recognised as active participants in vascular inflammation, as well as in prothrombotic complications of ...
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Soma, Prashilla; Van Marle-Koster, Este; Frylinck, L. (South African Society for Animal Science, 2014)Porcine stress syndrome (PSS) is a genetic disorder caused by a recessive mutation in the halothane (HAL) gene and results in sudden death of pigs when placed under stress during transport and pre-slaughtering conditions. ...
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Ellemdin, Shiraz; Soma, Prashilla; Hassen, M.I.E. (South African Academy of Family Practice/Primary Care, 2013)Coarctation of the aorta is a congenital condition generally, and may vary from mild to severe. Symptomatology depends on early or late presentation. Young patients may present within the first few weeks of life with poor ...
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Soma, Prashilla; Pretorius, Etheresia (BioMed Central, 2015-07)Accelerated atherosclerosis is the main underlying factor contributing to the high risk of atherothrombotic events in patients with diabetes mellitus and atherothrombotic complications are the main cause of mortality. ...
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Blom, Dirk J.; Breedt, Johannes; Burgess, Lesley J.; Ebrahim, Iftikhar O.; Soma, Prashilla; Van der Walt, Eugene; Naidoo, Poobalan; Van Tonder, Alet; Raal, Frederick J. (Clinics Cardive, 2019-09-21)BACKGROUND : Alirocumab reduces low-density lipoprotein cholesterol (LDL-C) levels by up to 61%. The ODYSSEY Open-Label Extension study investigated the effect of alirocumab in patients with heterozygous familial ...
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Pretorius, Etheresia; Akeredolu, Oore-Ofe; Soma, Prashilla; Kell, Douglas B. (Sage, 2017-02)We review the evidence that infectious agents, including those that become dormant within the host, have a major role to play in much of the etiology of rheumatoid arthritis and the inflammation that is its hallmark. This ...
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Phasha, Marry-Ann Ntanyane; Soma, Prashilla; Van Rooy, Mia-Jeanne; Phulukdaree, Alisa (Bentham Science Publishers, 2023-07)There is a rise in the number of individuals diagnosed with type 2 diabetes mellitus (T2DM) in South Africa. Cardiovascular disease is among the macrovascular complication of type 2 diabetes mellitus and accounts for the ...
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Soma, Prashilla; Bester, Janette (Frontiers Media S.A., 2022-06-15)Higher thrombotic burden in the acute phase of COVID-19 relies on a complex interplay between pro-inflammatory cytokine/chemokine release, increased endothelial dysfunction/ damage, and potential sepsis-induced coagulopathy ...
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Pretorius, Etheresia; Bester, Janette; Vermeulen, Natasha; Alummoottil, Sajee; Soma, Prashilla; Buys, A.V. (Antonia Vergina); Kell, Douglas B. (BioMed Central, 2015-03)We have noted in previous work, in a variety of inflammatory diseases, where iron dysregulation occurs, a strong tendency for erythrocytes to lose their normal discoid shape and to adopt a skewed morphology (as judged ...
Now showing items 1-20 of 30