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Browsing by UP Author "Laurens, Johannes B."
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Joubert, Annie M.; Van Zyl, Hermia; Laurens, Johannes B.; Lottering, Mona-Liza
(Centro Regional de Investigaciones Cientificas Y Tecnologicas / Universidad Nacional de Cuyo, 2009)
C2- and C4-position 17β-estradiol metabolites play an important role in breast carcinogenesis. 2-Hydroxyestradiol and 4-hydroxyestradiol are implicated in tumorigenesis via two pathways. These pathways entail increased ...
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Laurens, Johannes B.; Carstens, Pieter Albert, 1960-
(Health and Medical Publishing Group, 2020-10)
The legalisation of cannabis by the High Court of South Africa, which was confirmed by the Constitutional Court, imposes challenges to
occupational medical practitioners acting as medical review officers in compliance ...
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Oosthuizen, Nicholette M.; Laurens, Johannes B.
(Royal Society of Medicine Press, 2012-03)
BACKGROUND: It has been known for some time that the antiretroviral drug, efavirenz (EFV), cross-reacts in urine immunoassays for tetrahydrocannabinol (THC). Because published studies investigating this phenomenon are ...
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Bipath, Priyesh; Laurens, Johannes B.; Viljoen, Margaretha; Creative Studios, Dept of Education Innovation, University of Pretoria
(2008-11-12)
Tryptophan, an essential amino acid, follows important metabolic pathways for protein, niacin and serotonin synthesis. The kynurenine pathway is a major pathway for tryptophan degradation. Indications are that tryptophan ...
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Laurens, Johannes B.; Carstens, Pieter Albert, 1960-
(Health and Medical Publishing Group, 2020-12)
BACKGROUND. Prohibited substance regulation and compliance-testing programmes are required to minimise risks to health and safety in
the workplace due to inappropriate use of legal (alcohol, cannabis) and illegal substances. ...
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Marais, Adriaan Albertyn Scheepers; Laurens, Johannes B.
(Elsevier, 2008)
Amphetamine and related derivatives are widely abused central- and psychostimulants. Detection of certain derivatives, such as methcathinone, by commonly available immunoassay screening techniques is insufficient. Multi-analyte ...
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Sharma, Kamlesh; Laurens, Johannes B.; Pilcher, Lynne A.
(Routledge, 2009)
On exposure to the potential carcinogen 1,3-butadiene, the major
urinary metabolite in humans is N-acetyl-S-(3,4-dihydroxybutyl)cysteine. A
novel, stereoselective synthesis of this cysteine–butadiene metabolite has ...
