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Browsing by UP Author "Bipath, Priyesh"
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Viljoen, Margaretha; Bipath, Priyesh; Roos, J.L. (Johannes Louw)
(AOSIS, 2018-09-11)
Pellagra is characterised by dermatological, gastrointestinal and neuropsychiatric manifestations.
Millions contracted the disease and hundreds of thousands died between the time it was first recorded
until pellagra was ...
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Basson, Charlise; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Y.
(Wiley, 2023-07)
BACKGROUND : Cutaneous melanoma is a relentless form of cancer which continues to rise in incidence. Currently, cutaneous melanoma is the leading cause of skin cancer-related mortality, which can mainly be attributed to ...
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Thomas, Bianca; Bipath, Priyesh; Viljoen, Margaretha
(Makerere University Medical School, 2019-09)
BACKGROUND : Neopterin, a product of cell-mediated immunity, is a non-specific biomarker of inflammation. Plasma/serum is
generally the body fluid of choice for neopterin assessment, but urine is often used as it does ...
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Bekker, Melissa; Balt, Karlien; Bipath, Priyesh; Jordaan, J.C. (Joyce); Du Toit, Peet J.
(International Society for Neurofeedback & Research, 2021-09-30)
Neurofeedback has gained great interest as a noninvasive treatment for various disorders. However, there is still a lack in literature regarding the effects of infra-slow fluctuation (ISF) neurofeedback training. ISF ...
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Nkandeu, D.S. (Danielle Sandra); Joubert, Anna Margaretha; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Yvette Nkondo
(Wiley, 2024-06)
Cancer is the second leading cause of mortality worldwide. The development of anticancer therapy plays a crucial role in mitigating tumour progression and metastasis. Epithelioid hemangioendothelioma is a very rare cancer, ...
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Basson, Charlise; Phiri, Avulundiah Edwin; Gandhi, Manjunath; Anguelov, Roumen; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Yvette Nkondo
(Wiley, 2024-06)
CTCE-9908, a CXC chemokine receptor 4 (CXCR4) antagonist, prevents CXCR4 phosphorylation and inhibits the interaction with chemokine ligand 12 (CXCL12) and downstream signalling pathways associated with metastasis. This ...
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Basson, Charlise; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Y.
(Elsevier, 2024-12)
INTRODUCTION :
The inhibition of melanoma adhesion through adhesion molecules, such as integrins and E-cadherin, may represent a promising strategy for managing melanoma metastasis. Compounds, namely l-kynurenine (L-kyn) ...
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Basson, Charlise; Serem, June Cheptoo; Hlophe, Yvette Nkondo; Bipath, Priyesh
(Wiley, 2023-10)
The metastatic behavior of melanoma has accentuated the need for specific therapy
targets. Compounds, namely L‐kynurenine (L‐kyn), quinolinic acid (Quin), and kynurenic
acid (KA) previously displayed antiproliferative ...
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Cronje, Rouxzan; Beukes, Johanni; Masenge, Andries; Du Toit, P.J.; Bipath, Priyesh
(International Society for Neurofeedback & Research, 2024-03-29)
The aim of this study was to investigate whether the inflammatory marker neopterin and certain neurophysiological measurements could be used as complementary markers for stress and anxiety symptoms as determined by the ...
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Nkandeu, Danielle Sandra; Basson, Charlise; Joubert, Anna Margaretha; Serem, June Cheptoo; Bipath, Priyesh; Nyakudya, Trevor Tapiwa; Hlophe, Yvette Nkondo
(Wiley, 2022-08)
Cancer is the second leading cause of mortality worldwide. Skin cancer is the most
common cancer in South Africa with nearly 20,000 reported cases every year and
700 deaths. If diagnosed early, the 5‐year survival rate ...
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Basson, Charlise; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Yvette Nkondo
(Wiley, 2024-07)
Melanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L-kynurenine and quinolinic acid induce cytotoxicity ...
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Bipath, Priyesh; Laurens, Johannes B.; Viljoen, Margaretha; Creative Studios, Dept of Education Innovation, University of Pretoria
(2008-11-12)
Tryptophan, an essential amino acid, follows important metabolic pathways for protein, niacin and serotonin synthesis. The kynurenine pathway is a major pathway for tryptophan degradation. Indications are that tryptophan ...
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Bipath, Priyesh; Levay, Peter Ferenc; Olorunju, Steve; Viljoen, Margaretha
(Makerere University Medical School, 2015-06)
BACKGROUND : A general non-specific marker of disease activity that could alert the clinician and prompt further investigation
would be of value in patients with HIV/AIDS, especially in resource limited environments.
OBJECTIVE ...
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Viljoen, Margaretha; Bipath, Priyesh; Tosh, Cheryl A.
(Cambridge University Press, 2021-06)
OBJECTIVE : Pellagra is a nutritional deficiency disease associated with niacin (vitamin B3) deficiency. The history of pellagra is well documented for Europe and the USA, but less is known about the prevalence in sub-Saharan ...
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Anguelov, Roumen; Manjunath, Gandhi; Phiri, Avulundiah Edwin; Nyakudya, Trevor Tapiwa; Bipath, Priyesh; Serem, June Cheptoo; Hlophe, Yvette Nkondo
(Oxford University Press, 2023-09)
Please read abstract in the article.
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Bipath, Priyesh; Levay, Peter Ferenc; Viljoen, Margaretha
(BioMed Central, 2016-02-17)
BACKGROUND : The essential amino acid tryptophan cannot be synthesised in the body and must be acquired
through dietary intake. Oxidation of tryptophan, due to immune induction of the enzyme indoleamine 2,3-
dioxygenase ...
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Basson, Charlise; Serem, June Cheptoo; Hlophe, Yvette Nkondo; Bipath, Priyesh
(Wiley, 2023-09)
INTRODUCTION : The activation of the kynurenine pathway in cancer progression and metastasis through immunomodulatory pathways has drawn attention to the potential for kynurenine pathway inhibition. The activation of the ...