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Browsing by UP Author "Bipath, Priyesh"
Now showing items 1-16 of 16
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Viljoen, Margaretha; Bipath, Priyesh; Roos, J.L. (Johannes Louw) (AOSIS, 2018-09-11)Pellagra is characterised by dermatological, gastrointestinal and neuropsychiatric manifestations. Millions contracted the disease and hundreds of thousands died between the time it was first recorded until pellagra was ...
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Basson, Charlise; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Y. (Wiley, 2023-07)BACKGROUND : Cutaneous melanoma is a relentless form of cancer which continues to rise in incidence. Currently, cutaneous melanoma is the leading cause of skin cancer-related mortality, which can mainly be attributed to ...
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Thomas, Bianca; Bipath, Priyesh; Viljoen, Margaretha (Makerere University Medical School, 2019-09)BACKGROUND : Neopterin, a product of cell-mediated immunity, is a non-specific biomarker of inflammation. Plasma/serum is generally the body fluid of choice for neopterin assessment, but urine is often used as it does ...
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Bekker, Melissa; Balt, Karlien; Bipath, Priyesh; Jordaan, J.C. (Joyce); Du Toit, Peet J. (International Society for Neurofeedback & Research, 2021-09-30)Neurofeedback has gained great interest as a noninvasive treatment for various disorders. However, there is still a lack in literature regarding the effects of infra-slow fluctuation (ISF) neurofeedback training. ISF ...
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Nkandeu, D.S. (Danielle Sandra); Joubert, Anna Margaretha; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Yvette Nkondo (Wiley, 2024-06)Cancer is the second leading cause of mortality worldwide. The development of anticancer therapy plays a crucial role in mitigating tumour progression and metastasis. Epithelioid hemangioendothelioma is a very rare cancer, ...
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Basson, Charlise; Phiri, Avulundiah Edwin; Gandhi, Manjunath; Anguelov, Roumen; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Yvette Nkondo (Wiley, 2024-06)CTCE-9908, a CXC chemokine receptor 4 (CXCR4) antagonist, prevents CXCR4 phosphorylation and inhibits the interaction with chemokine ligand 12 (CXCL12) and downstream signalling pathways associated with metastasis. This ...
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Basson, Charlise; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Y. (Elsevier, 2024-12)INTRODUCTION : The inhibition of melanoma adhesion through adhesion molecules, such as integrins and E-cadherin, may represent a promising strategy for managing melanoma metastasis. Compounds, namely l-kynurenine (L-kyn) ...
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Basson, Charlise; Serem, June Cheptoo; Hlophe, Yvette Nkondo; Bipath, Priyesh (Wiley, 2023-10)The metastatic behavior of melanoma has accentuated the need for specific therapy targets. Compounds, namely L‐kynurenine (L‐kyn), quinolinic acid (Quin), and kynurenic acid (KA) previously displayed antiproliferative ...
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Nkandeu, Danielle Sandra; Basson, Charlise; Joubert, Anna Margaretha; Serem, June Cheptoo; Bipath, Priyesh; Nyakudya, Trevor Tapiwa; Hlophe, Yvette Nkondo (Wiley, 2022-08)Cancer is the second leading cause of mortality worldwide. Skin cancer is the most common cancer in South Africa with nearly 20,000 reported cases every year and 700 deaths. If diagnosed early, the 5‐year survival rate ...
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Basson, Charlise; Serem, June Cheptoo; Bipath, Priyesh; Hlophe, Yvette Nkondo (Wiley, 2024-07)Melanoma is an aggressive malignancy and remains a major cause of skin cancer mortality, highlighting the need for new treatment strategies. Recent findings revealed that L-kynurenine and quinolinic acid induce cytotoxicity ...
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Newly developed method for quantification of tryptophan and its metabolites : clinical application Bipath, Priyesh; Laurens, Johannes B.; Viljoen, Margaretha; Creative Studios, Dept of Education Innovation, University of Pretoria (2008-11-12)Tryptophan, an essential amino acid, follows important metabolic pathways for protein, niacin and serotonin synthesis. The kynurenine pathway is a major pathway for tryptophan degradation. Indications are that tryptophan ...
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A non-specific biomarker of disease activity in HIV/AIDS patients from resource-limited environments Bipath, Priyesh; Levay, Peter Ferenc; Olorunju, Steve; Viljoen, Margaretha (Makerere University Medical School, 2015-06)BACKGROUND : A general non-specific marker of disease activity that could alert the clinician and prompt further investigation would be of value in patients with HIV/AIDS, especially in resource limited environments. OBJECTIVE ...
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Viljoen, Margaretha; Bipath, Priyesh; Tosh, Cheryl A. (Cambridge University Press, 2021-06)OBJECTIVE : Pellagra is a nutritional deficiency disease associated with niacin (vitamin B3) deficiency. The history of pellagra is well documented for Europe and the USA, but less is known about the prevalence in sub-Saharan ...
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Anguelov, Roumen; Manjunath, Gandhi; Phiri, Avulundiah Edwin; Nyakudya, Trevor Tapiwa; Bipath, Priyesh; Serem, June Cheptoo; Hlophe, Yvette Nkondo (Oxford University Press, 2023-09)Please read abstract in the article.
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Bipath, Priyesh; Levay, Peter Ferenc; Viljoen, Margaretha (BioMed Central, 2016-02-17)BACKGROUND : The essential amino acid tryptophan cannot be synthesised in the body and must be acquired through dietary intake. Oxidation of tryptophan, due to immune induction of the enzyme indoleamine 2,3- dioxygenase ...
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Basson, Charlise; Serem, June Cheptoo; Hlophe, Yvette Nkondo; Bipath, Priyesh (Wiley, 2023-09)INTRODUCTION : The activation of the kynurenine pathway in cancer progression and metastasis through immunomodulatory pathways has drawn attention to the potential for kynurenine pathway inhibition. The activation of the ...
Now showing items 1-16 of 16