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Browsing Research Articles (University of Pretoria) by Author "Oberholzer, Hester Magdalena"
Now showing items 1-20 of 30
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Arbi, Sandra; Bester, Megan Jean; Pretorius, Liselle; Oberholzer, Hester Magdalena (Taylor and Francis, 2021)The aim of this study was to identify cardiovascular effects of relevant concentrations of Cd and Hg alone and in combination as a mixture in water. This was achieved by administering to male Sprague–Dawley rats via gavage ...
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Janse van Rensburg, Maxine; Bester, Megan; Van Rooy, Mia-Jeanne; Oberholzer, Hester Magdalena (Sage, 2023-08)Cardiovascular diseases (CVD) are a common global cause of death and are therefore a major health concern. Inhaled or ingested environmental heavy metals contribute to the development of CVD. The aim of this study was to ...
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Draper, Maxine; Bester, Megan; Van Rooy, Mia-Jeanne; Oberholzer, Hester Magdalena (Taylor and Francis, 2023)Exposure to environmental metal pollutants is linked to oxidative stress and the subsequent development of neurological disease. In this study, the effects of copper, manganese, and mercury, were evaluated at X100 the World ...
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Pretorius, Etheresia; Oberholzer, Hester Magdalena; Van der Spuy, Wendy Jeannette; Meiring, Johannes H. (Springer, 2010-01)During aging, changes in vasculature, haemostasis and endothelium, including alterations of platelets, coagulation and fibrinolytic factors, occur. Research has also reported that healthy, aged individuals have heightened ...
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Pretorius, Etheresia; Vieira, Warren Antonio; Oberholzer, Hester Magdalena; Auer, Roland E.J. (Sociedad Chilena de Anatomía, 2009-03)The purpose of the present study was to compare the platelet and fibrin network ultrastructure of humans to eight different animal species in order to determine the differences between human and animal platelet and fibrin ...
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Pretorius, Etheresia; Windberger, Ursula B.; Oberholzer, Hester Magdalena; Auer, Roland E.J. (Agricultural Research Council, ARC-OVI and the University of Pretoria, 2010-11)A cerebrovascular accident or stroke is a rare condition in dogs, but previous studies suggest that it is now increasingly being recognised. Platelets and fibrin networks are involved in haemostasis, which is disrupted ...
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Pretorius, Etheresia; Oberholzer, Hester Magdalena; Becker, Piet J. (African Networks on Ethnomedicines, 2009)The plant Withania somnifera (Linn.) (Solanacea) is a well-known herbal medicine used in many parts of the world. It has anti-inflammatory, antioxidant, and antitumor as well as neural protective properties. It seems as ...
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Pretorius, Etheresia; Swanepoel, A.C. (Albe Carina); Oberholzer, Hester Magdalena; Van der Spuy, Wendy Jeannette; Duim, Wiebren; Wessels, Pieter Frederik (Springer, 2011-05)Stroke is one of the leading causes of death worldwide. Formation of a fibrin clot is controlled by a group of tightly regulated plasma proteases and cofactors and a change in the fibrin fiber formation causes an alteration ...
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Oberholzer, Hester Magdalena; Van der Schoor, Ciska; Taute, Helena; Bester, Megan Jean (Wiley, 2015-08)Exposure to drugs during pregnancy is a major concern, as some teratogenic compounds can influence normal foetal development. Although the use of drugs during pregnancy should generally be avoided, exposure of the ...
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Karusseit, V.O.L. (Otto); Oberholzer, Hester Magdalena; Irsigler, N.G.; Olorunju, Steve A.S. (Elsevier, 2014)BACKGROUND : Resectional breast surgery has become less extensive. Dissection on plane of the superficial fascia covering the breast (juxtacapsular) is used during various procedures for retention of the appearance of ...
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Van der Schoor, Ciska; Oberholzer, Hester Magdalena; Bester, Megan Jean; Van Rooy, Mia-Jeanne (Informa Healthcare, 2014-12)Sibutramine is used in the treatment of obesity due to its ability to influence feelings of hunger and satiety by inhibiting the re-uptake of serotonin and noradrenalin in the central nervous system (CNS). Sibutramine ...
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Venter, Chantelle; Oberholzer, Hester Magdalena; Cummings, Franscious Riccardo; Bester, Megan Jean (Wiley, 2017-08)Heavy metal pollution has increased in the last decades. Water sources are contaminated and human exposure is often long term exposure to variable amounts of different metals. In this study, male Sprague-Dawley rats were ...
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Venter, Chantelle; Van der Merwe, Christiaan F.; Oberholzer, Hester Magdalena; Bester, Megan Jean; Taute, Helena (Wiley, 2013)Fixation of biological samples is an important process especially related to histological and ultrastructural studies. Chemical fixation was the primary method of fixing tissue for transmission electron microscopy for ...
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Venter, Chantelle; Olivier, Anel; Taute, Helena; Oberholzer, Hester Magdalena (Taylor and Francis, 2020)The mining sector in South Africa is expected to be the fifth largest in the world. Both mining and transport are the most common reasons for an increased risk of human exposure to heavy metal contamination in South Africa. ...
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Rabie, E.; Serem, June Cheptoo; Oberholzer, Hester Magdalena; Gaspar, Anabella Regina Marques; Bester, Megan Jean (Taylor and Francis, 2016-03)Antibacterial activity of honey is due to the presence of methylglyoxal (MGO), H2O2, bee defensin as well as polyphenols. High MGO levels in manuka honey are the main source of antibacterial activity. Manuka honey has ...
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Venter, Chantelle; Oberholzer, Hester Magdalena; Taute, Helena; Cummings, Franscious R.; Bester, Megan Jean (Taylor & Francis, 2015-06)Excessive agriculture, transport and mining often lead to the contamination of valuable water resources. Communities using this water for drinking, washing, bathing and the irrigation of crops are continuously being exposed ...
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Dhanraj, Priyanka; Venter, Chantelle; Bester, Megan Jean; Oberholzer, Hester Magdalena (Taylor and Francis, 2020)Increased anthropogenic activity and subsequent environmental exposure to heavy metals induce the production of reactive oxygen species (ROS), which increases oxidative stress and the risk of associated diseases. The aim ...
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Pretorius, Etheresia; Crookes, R.; Oberholzer, Hester Magdalena; Van der Spuy, Wendy Jeannette (Elsevier, 2010-12)In thrombotic events and diseases such as cancer, HIV/AIDS, dysfibrinogenaemia, as well as acute incidents (e.g. burn wounds), ultrastructure of platelets and fibrin networks change. In the current study, we compare the ...
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Oberholzer, Hester Magdalena; Vieira, Warren Antonio; Pretorius, Etheresia (Sociedad Chilena de Anatomía, 2009-09)Modul8® is a composite mixture of natural products that are known to be an immunomodulator. In the current study the effect of this immunomodulator is tested on an experimental asthmatic BALB/c mouse model to investigate ...
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Koopsamy Naidoo, Sirasha Venketsamy; Bester, Megan Jean; Arbi, Sandra; Venter, Chantelle; Dhanraj, Priyanka; Oberholzer, Hester Magdalena (Elsevier, 2019-07)Environmental presence and human exposure to heavy metals in air and cigarette smoke has led to a worldwide increase in respiratory disease. The effects of oral exposure to heavy metals in liver and kidney structure and ...
Now showing items 1-20 of 30