Reconciliation is usually seen in connection with the relationships between God and his people, and the mutual relationships between people, especially believers in Christ. In Col 1, however, Paul relates reconciliation to all things in heaven and on earth. The implications of this statement for the life and work of the church and her members need further reflection. In this article, attention is given to the dysfunctional interactions between socio-cultural, ecological, economical, political and other systems in the Southern African context. These dysfunctional interactions cause widespread poverty, ecological degradation and social disruption. Church members can see it as their calling to work for the functional integration of these systems, in their own lifestyles as well as in society in general, in order to promote the wellbeing of society.