Additional file 1: Overview of the Diffany framework. Overview of the
Diffany framework and its typical usage in a specific experiment involving
the perturbation of an interactome under one or more conditions. (DOCX
183 KB)
Additional file 2: List of differentially expressed genes. Dataset of
differentially expressed genes, as originally published by [24]. Here, those
genes are listed that are differentially expressed in at least one of the 4 time
points and in either the more (FDR < 0.05) or less (FDR < 0.1) stringent
dataset. This file also depicts the overlap of genes at the different time
points. (XLSX 514 KB)
Additional file 3: Experimental methodology. Methodological details
of the experiments performed on the putative HY5 regulator. (DOCX 22 KB)
Additional file 4: Figure showing the experimental validation of the
putative HY5 regulator. Detailed analysis of hy5 mutants and WT lines
when exposed to mannitol-induced stress, comparing both leaf area as
well as expression levels of putative HY5-target genes such as TCH3 and
MYB51. (DOCX 472 KB)