dc.contributor.author |
Wichmann, Janine
|
|
dc.contributor.author |
Sjoberg, Karin
|
|
dc.contributor.author |
Tang, Lin
|
|
dc.contributor.author |
Haeger-Eugensson, Marie
|
|
dc.contributor.author |
Rosengren, Annika
|
|
dc.contributor.author |
Andersson, Eva M.
|
|
dc.contributor.author |
Barregard, Lars
|
|
dc.contributor.author |
Sallsten, Gerd
|
|
dc.date.accessioned |
2015-06-05T09:08:13Z |
|
dc.date.available |
2015-06-05T09:08:13Z |
|
dc.date.issued |
2014-07-29 |
|
dc.description.abstract |
BACKGROUND: The relative importance of different sources of air pollution for cardiovascular disease is unclear. The
aims were to compare the associations between acute myocardial infarction (AMI) hospitalisations in Gothenburg,
Sweden and 1) the long-range transported (LRT) particle fraction, 2) the remaining particle fraction, 3) geographical
air mass origin, and 4) influence of local dispersion during 1985–2010.
METHODS : A case-crossover design was applied using lag0 (the exposure the same day as hospitalisation), lag1
(exposure one day prior hospitalisation) and 2-day cumulative average exposure (CA2) (mean of lag0 and lag1). The
LRT fractions included PMion (sum of sulphate, nitrate and ammonium) and soot measured at a rural site. The
difference between urban PM10 (particulate matter with an aerodynamic diameter smaller than 10 μm) and rural
PMion was a proxy for locally generated PM10 (PMrest). The daily geographical origin of air mass was estimated as
well as days with limited or effective local dispersion. The entire year was considered, as well as warm and cold
periods, and different time periods.
RESULTS : In total 28 215 AMI hospitalisations occurred during 26 years. PM10, PMion, PMrest and soot did not influence
AMI for the entire year. In the cold period, the association was somewhat stronger for PMrest than for urban PM10; the
strongest associations were observed during 1990–2000 between AMI and CA2 of PMrest (6.6% per inter-quartile range
(IQR), 95% confidence interval 2.1 to 11.4%) and PM10 (4.1%, 95% CI 0.2% − 8.2%). Regarding the geographical air mass
origins there were few associations. Days with limited local dispersion showed an association with AMI in the cold
period of 2001–2010 (6.7%, 95% CI 0.0% − 13.0%).
CONCLUSIONS : In the cold period, locally generated PM and days with limited local dispersion affected AMI
hospitalisations, indicating importance of local emissions from e.g. traffic. |
en_ZA |
dc.description.librarian |
am2015 |
en_ZA |
dc.description.sponsorship |
The Swedish Research Council Formas funded the study. |
en_ZA |
dc.description.uri |
http://www.ehjournal.net |
en_ZA |
dc.identifier.citation |
Wichmann, J, Sjoberg, K, Tang, L, Haeger-Eugensson, M, Rosengren, A, Andersson, EM, Barregard, L & Sallsten, G 2014, 'The effect of secondary inorganic aerosols, soot and the geographical origin of air mass on acute myocardial infarction hospitalisations in Gothenburg, Sweden during 1985–2010 : a case-crossover study', Environmental Health, vol. 13, art. no. 61, pp. 1-16. |
en_ZA |
dc.identifier.issn |
1476-069X |
|
dc.identifier.other |
10.1186/1476-069X-13-61 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/45428 |
|
dc.language.iso |
en |
en_ZA |
dc.publisher |
BioMed Central |
en_ZA |
dc.rights |
© 2014 Wichmann et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the
Creative Commons Attribution License. |
en_ZA |
dc.subject |
Air pollution |
en_ZA |
dc.subject |
Secondary inorganic aerosols |
en_ZA |
dc.subject |
Soot |
en_ZA |
dc.subject |
Geographical air mass origin |
en_ZA |
dc.subject |
Hospitalisations |
en_ZA |
dc.subject |
Gothenburg |
en_ZA |
dc.subject |
Case-crossover |
en_ZA |
dc.subject |
Acute myocardial infarction (AMI) |
en_ZA |
dc.title |
The effect of secondary inorganic aerosols, soot and the geographical origin of air mass on acute myocardial infarction hospitalisations in Gothenburg, Sweden during 1985 - 2010 : a case-crossover study |
en_ZA |
dc.type |
Article |
en_ZA |