Cardiac glycoside poisoning in sheep caused by Urginea physodes (Jacq.) Bak. and the isolated physodine A

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dc.contributor.author Nel, P.W.
dc.contributor.author Jordaan, P.
dc.contributor.author Anderson, L.A.P.
dc.contributor.author Kellerman, T. Stephanus
dc.contributor.author Reid, Clare
dc.contributor.author Schultz, R.A. (Rowena Anitra)
dc.contributor.editor Bigalke, R.D.
dc.date.accessioned 2014-11-17T08:34:31Z
dc.date.available 2014-11-17T08:34:31Z
dc.date.created 2014
dc.date.issued 1987
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en_US
dc.description.abstract Urginea physodes (Jacq.) Bak., a species closely related to or possibly synonymous with U. pusilla, is described and its distribution given. Four bufadienolides were isolated from U. physodes and the approximated LD₅₀ and cumulative effect of some of them determined in guinea pigs. The most toxic one proved to be mildly cumulative. Typical signs of acute cardiac glycoside poisoning, involving the locomotory, gastro-intestinal, respiratory and cardiac systems, were seen in the field cases and/or were experimentally induced by the plant. Similar signs could also be induced by injecting the isolated bufadienolide, physodine A, to a sheep. en_US
dc.description.librarian lmchunu2014 en_US
dc.description.librarian mn2014
dc.identifier.citation Nel, PW, Schultz, RA, Jordaan, P, Anderson, LAP, Kellerman, TS & Reid, C 1987, 'Cardiac glycoside poisoning in sheep caused by Urginea physodes (Jacq.) Bak. and the isolated physodine A’, Onderstepoort Journal of Veterinary Research, vol. 54, no. 4, pp. 641-644. en_US
dc.identifier.issn 0330-2465
dc.identifier.uri http://hdl.handle.net/2263/42588
dc.language.iso en en_US
dc.publisher Published by the Government Printer, Pretoria. en_US
dc.rights ©ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Dept. of Library Services (digital). en_US
dc.subject Veterinary medicine en_US
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title Cardiac glycoside poisoning in sheep caused by Urginea physodes (Jacq.) Bak. and the isolated physodine A en_US
dc.type Article en_US


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