Currently, the Lyssavirus genus is composed of four serotypes and the ungrouped European bat lyssaviruses (EBL). Using previously described PCR amplification and direct sequencing methods, the N
genes of 70 representative lyssaviruses collected from 40 different countries were examined. From the
results, a phylogenetic tree with six branches (genotypes) was constructed: genotypes 1-4 correlated
with the classification of serotypes 1-4 and in addition EBL 1 and EBL 2 were identified as two further
genotypes (5 and 6). Analysis of the 51 rabies (genotype 1) viruses in the study identified nine distinct
groups which could be correlated with their geographical origins.
A comparison of the six genotypes with four principal Vesiculovirus serotypes showed that their relationship
was closer than that of even the two most closely related Vesiculovirus serotypes.
Antigenic site sequences of isolates from vaccine/treatment failures were similar to vaccine and field
strains, suggesting that failures were not due to genetic variation at the N protein level.
The articles have been scanned in colour with a HP Scanjet 5590; 600dpi.
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Cilliers, Jakkie; Schunemann, Julia; Moyer, Jonathan D.(Institute for Security Studies, 2015-03)
This paper explores the changing power capabilities of Algeria, Egypt, Ethiopia,
Nigeria, and South Africa (the ‘Big Five’) over the next 25 years. Of these countries,
Ethiopia and Nigeria are forecast to increase their ...
Bungane, Mbulelo Shadrack(University of Pretoria, 2014)
The study examines SA‟s human rights diplomacy in Africa and the selected countries, namely Libya, Nigeria, the Sudan and Zimbabwe during the presidencies of Presidents Mandela and Mbeki. When SA decided to follow an ethics ...
Venkatraman, Kubashnee(University of Pretoria, 2014)
Shockwaves from the 2007–2010 financial crises caused a huge economic downturn and impacted countries and market centres globally. This blemished the reputation of the banks with many blaming the global financial crisis ...