Research Articles (Pharmacology)

Research Articles (Pharmacology)

 

Recent Submissions

  • Outhoff, Kim (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2016)
    Intermittent or acute insomnia is common and may sometimes require short term treatment with approved hypnotic agents. A diagnosis of insomnia disorder, however, indicates that poor night-time sleep is chronic and is ...
  • Outhoff, Kim (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2016-05)
    Bipolar Disorder (BD) is characterised by alternating discrete episodes of depression and mania. Rational pharmacotherapy necessitates an appreciation of these different phases and of the possible underlying pathophysiology. ...
  • Ahmed, Marwan Awad; Muntingh, George L.; Rheeder, Paul (BioMed Central, 2016-10-07)
    BACKGROUND : The association between long-term metformin use and low vitamin B12 levels has been proven. However, the prevalence estimates of metformin-induced vitamin B12 deficiency showed considerable variation among ...
  • Ahmed, Marwan Awad (Canadian Society for Pharmaceutical Sciences, 2016-10-25)
    The association between metformin use and low vitamin B12 levels in type 2 diabetes mellitus patients is well-established. However, many aspects of the topic remain to be elucidated. There is still controversy on the ...
  • Muntingh, George L. (Medpharm Publications, NISC (Pty) Ltd, Taylor & Francis, and Informa business, 2016)
    Vitamin D is a fat-soluble vitamin that plays an important role in bone metabolism and seems to have some anti-inflammatory and immune-modulating properties. For most people sunlight is the most important source of vitamin ...
  • Steenkamp, Vanessa; Mohamed, Khaled M. (Wiley, 2016-12)
    Cases of poisoning by p-phenylenediamine (PPD) are detected sporadically. Recently an article on the development and validation of a LC-MS/MS method for the detection of PPD and its metabolites, N-acetyl-p-phenylenediamine ...
  • Snyman, Jacques Rene; Van Rensburg, Elizabeth J.; Laurens, Ilze; Mer, Mervyn; Van Tonder, Jacob John (Dove Medical Press, 2016-11-17)
    INTRODUCTION : Clinicians’ skepticism, fueled by evidence of inferiority of some multisource generic antimicrobial products, results in the underutilization of more cost-effective generics, especially in critically ill ...
  • Outhoff, Kim (MedPharm Publications, 2016)
    The gastrointestinal tract is exquisitely sensitive to different physical and psychological stressors. Irritable bowel syndrome (IBS) may be viewed as a disorder caused by stress-induced dysregulation of the complex ...
  • Muntingh, George L. (MedPharm Publications, 2016)
    In the past 10 years or so, many alternatives to warfarin have been developed the first being the novel oral anticoagulants (NOAC) or better referred to as direct oral anticoagulants (DOAC) or target-specific oral ...
  • Liebenberg, J.; Du Toit-Prinsloo, Lorraine; Steenkamp, Vanessa; Saayman, Gert (Health and Medical Publishing Group, 2016-10)
    Background. Globally, illicit drugs are responsible for many fatalities annually, yet accurate data on the nature and extent of these deaths in South Africa (SA) are lacking. Objectives. To investigate the presence and ...
  • Marais, Andre (MedPharm Publications, 2016)
    Obesity is a growing phenomenon and a global concern. It is well-known that it plays a significant role in the development of several preventable diseases. The physiological mechanisms in regulating energy intake and ...
  • Marais, Andre (MedPharm Publications, 2016)
    Erectile dysfunction (ED) is a trivial condition with a prevailing incidence worldwide. Phosphodiesterase-5 inhibitors (PDE-5) have revolutionised the treatment of ED and are regarded as one of the most successful drug ...
  • Marais, Andre (Plus 50 Media (Pty) Ltd., 2016-08)
    Current life expectancy, as determined by the World Health Organization in 2015, estimates males to live for about 71 years and females for approximately 73 years. On average, South Africa has lower life expectancy, with ...
  • Outhoff, Kim (MedPharm Publications, 2016)
    The anxiety disorders, obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD) are common and debilitating, often coexist with medical and psychiatric conditions, and usually require long-term ...
  • Greeff, O.B.W. (Oppel Bernhardt Wilhelm), 1948- (MedPharm Publications, 2016)
    About 60-80% of patients visiting a pharmacy have at some stage in their lives suffered from low back pain. The annual incidence in adults aged 35-55 years in developed countries is up to 45%. The differential diagnosis ...
  • Marais, Andre (Plus 50 Media (Pty) Ltd, 2016-06)
    To wake up every day with some kind of body pain or stiff muscles is a common occurrence as one grows older. This can be attributed to a variety of conditions; some are related to an increase in age, while others may have ...
  • Outhoff, Kim (MedPharm Publications, 2016)
    Intermittent or acute insomnia is common, and may sometimes require short-term treatment with an approved hypnotic agent. A diagnosis of insomnia disorder, however, indicates that night-time sleep is of poor quality and ...
  • Marais, Andre (MedPharm Publications, 2016)
    Hypercholesterolaemia is a chronic disease that affects up to 53% of the global population.1 Lifestyle modification and early diagnosis plays an important role in the management of this condition. Various cholesterol ...
  • Outhoff, Kim (MedPharm Publications, 2016)
    Magnesium is a chemical element used by every organ in the body, especially the brain, skeletal muscles and the heart. It functions as a cofactor in approximately 600 enzyme systems that regulate many different biochemical ...
  • Marais, Andre (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2016)
    Allergic conjunctivitis is a common condition encountered by the healthcare professional. Several factors have been implicated as possible causes and almost all involve an IgE mediated immune response. Symptoms may vary ...

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