Significant differences as well as similarities between Islam and Christianity in the areas of the transcendence of God is the main discussion of the thesis. The investigation of the transcendence of God in the Bible and the Qur’an is within the limits of corresponding relationship accounts of God with Adam, Abraham, and Moses. Selected passages are used as examples to fulfil the aim of the study. Through this study an attempt is also made to determine what constitutes different aspects of theologies and practices of Christianity and Islam. The preliminary preparation of the study and the orientation of the readers into the transcendence of God are dealt with in the first three chapters: Chapter 1 presents an overview of the research as well as the various aspects of research methodology, chapter 2 describes the similarities and differences of the Qur’an and the Bible in order to present an appropriate approach to the exegesis of the selected passages, and chapter 3 establishes the theological issues of the transcendence of God from the views of both Christian and Muslim scholars. The main discussion of the transcendence of God unfolds in chapters 4 and 5. Chapter 4 investigates how God reveals his will in respect to the Qur’an and the Bible, particularly the Old Testament, and describes and analyses the transcendence of God revealed in the Old Testament and the Qur’an within the limits of the parallel passages dealing with Adam, Abraham, and Moses. Chapter 5 carries over the results of chapter 4 to find the cause of the differences between the corresponding episodes of the Old Testament and the Qur’an with regard to the transcendence of God, and analyses the implications of the transcendence of God with regard to the differences in Christianity and Islam theology. Finally, chapter 6 concludes the study as well as presents implications and solutions for the Christian-Muslim conflicts and the necessity for further studies. In conclusion, the exegesis of identical passages concerning God’s relationship with man found in both the Qur’an and the Bible establishes that the Qur’an presupposes that God, maintaining absolute transcendence from creation, will not allow his immanent state with man. Thus, Muslims can only have a transcendent relationship with God, which diminishes their ability to know God, and closes the door to personal relationships between God and man. The lack of God’s personal relationship with man has been a key factor in shaping the theology of Islam. In the Bible, on the other hand, God’s relationship with man is expressed in both his transcendence and immanence. God first wanted his immanent state with man, but due to man’s sinful state the ontological transcendent relationship has been established. God, in turn, uses his transcendence as a method of immanence with man. This transcendence-immanence of God is evident through Christian theology which can be expressed as God’s horizontal-vertical relationship compared to the vertical relationship of God in Islam.