dc.contributor.author |
Janse van Rensburg, Estrelita
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dc.contributor.author |
Engelbrecht, Susan
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dc.contributor.author |
Van Heerden, Willem Francois Petrus
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dc.contributor.author |
Raubenheimer, E.J.
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dc.contributor.author |
Schoub, Barry D.
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dc.date.accessioned |
2007-07-03T13:52:12Z |
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dc.date.available |
2007-07-03T13:52:12Z |
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dc.date.issued |
1996-03 |
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dc.description |
This article was co-written by Prof Janse van Rensburg and Prof Van Heerden before they joined the University of Pretoria. |
en |
dc.description.abstract |
BACKGROUND: The incidence of oral squamous cell carcinoma (OSCC) is on the increase in developing countries. MATERIALS AND METHODS: Formalin fixed paraffin embedded blocks of OSCCs from a black South African population sample of peri-urban and rural origin were selected as follows: Group 1 - 57 OSCCs with a mean age of 59 years; Group 2 - 43 OSCCs all cases younger than 40 years; Group 3 - 46 OSCCs with blocks containing only tumour tissue without any normal epithelium and Group 4, a control group of 38 non-neoplastic epithelial lesions. Type specific primers were used in a standard PCR to amplify a segment of the E6 region of HPV 6, 11, 16 and 18. RESULTS: HPV 11 and 16 DNA were found in one sample each from groups 1 and 2 respectively. CONCLUSION: HPV is not an etiologic factor in the development of OSCC in the population studied. |
en |
dc.format.extent |
8503 bytes |
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dc.format.mimetype |
application/pdf |
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dc.identifier.citation |
Van Rensburg, EJ, Engelbrecht, S, Van Heerden, WFP, Raubenheimer, EJ & Schoub, BD 1996, 'Human papillomavirus DNA in oral squamous cell carcinomas from an African population sample', Anticancer Research, vol. 16, no. 2, pp. 969-973. [http://www.iiar-anticancer.org/research/research_index.htm] |
en |
dc.identifier.issn |
0250-7005 |
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dc.identifier.uri |
http://hdl.handle.net/2263/2867 |
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dc.language.iso |
en |
en |
dc.publisher |
International Institute of Anticancer Research |
en |
dc.rights |
International Institute of Anticancer Research.
The publisher prohibits open access to the full text of this article. |
en |
dc.subject |
Oral squamous cell carcinoma |
en |
dc.subject |
Developing countries |
en |
dc.subject.lcsh |
Mouth -- Cancer -- Blacks -- South Africa |
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dc.subject.lcsh |
Papillomaviruses -- South Africa |
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dc.title |
Human papillomavirus DNA in oral squamous cell carcinomas from an African population sample |
en |
dc.type |
Article |
en |