Children with limited speech using graphic symbols for communication often express themselves predominantly through single symbols rather than symbol combinations. This study aimed to investigate the effect of an intervention strategy that was incorporated into shared storybook reading on the production of graphic symbol combinations. Three children between the ages of 7;9 (years;months) and 10;8 with limited speech and physical impairments participated in the study. A multiple probe design across behaviours (3 different types of semantic symbol combinations) was used, replicated across the 3 participants. Intervention entailed prompting the production of strategic symbol combinations (generated from a matrix) during shared storybook reading by using a prompting hierarchy. The participants’ production of combinations targeted during intervention as well as their ability to generalize to nontarget combinations from the matrix was monitored using a probe test (picture description task). All 3 participants showed some gains in acquiring the combinations and generalizing to nontarget combinations, as measured by the probe test. While 1 participant showed convincing effects, the other 2 showed lower effects. Lower effects may be partly ascribed to participant characteristics as well as to the discrepancies between the intervention and probe contexts. All participants performed better within the shared storybook reading context. Results suggest that the production of symbol combinations can be facilitated during shared storybook reading and that the matrix strategy promotes generalization to untrained semantic combinations. However, participant gains may not reflect immediately in formal testing situations.