dc.contributor.author |
Tchouassi, David Poumo
|
|
dc.contributor.author |
Sang, Rosemary
|
|
dc.contributor.author |
Sole, Catherine L.
|
|
dc.contributor.author |
Bastos, Armanda D.S.
|
|
dc.contributor.author |
Teal, Peter E.A.
|
|
dc.contributor.author |
Borgemeister, Christian
|
|
dc.contributor.author |
Torto, Baldwyn
|
|
dc.date.accessioned |
2013-03-20T07:51:25Z |
|
dc.date.available |
2013-03-20T07:51:25Z |
|
dc.date.issued |
2013-01-10 |
|
dc.description.abstract |
Rift Valley fever (RVF), a mosquito-borne zoonosis, is a major public health and veterinary problem in sub-Saharan Africa.
Surveillance to monitor mosquito populations during the inter-epidemic period (IEP) and viral activity in these vectors is
critical to informing public health decisions for early warning and control of the disease. Using a combination of field
bioassays, electrophysiological and chemical analyses we demonstrated that skin-derived aldehydes (heptanal, octanal,
nonanal, decanal) common to RVF virus (RVFV) hosts including sheep, cow, donkey, goat and human serve as potent
attractants for RVFV mosquito vectors. Furthermore, a blend formulated from the four aldehydes and combined with CO2-
baited CDC trap without a light bulb doubled to tripled trap captures compared to control traps baited with CO2 alone. Our
results reveal that (a) because of the commonality of the host chemical signature required for attraction, the host-vector
interaction appears to favor the mosquito vector allowing it to find and opportunistically feed on a wide range of
mammalian hosts of the disease, and (b) the sensitivity, specificity and superiority of this trapping system offers the
potential for its wider use in surveillance programs for RVFV mosquito vectors especially during the IEP. |
en |
dc.description.librarian |
am2013 |
en |
dc.description.librarian |
ab2013 |
|
dc.description.sponsorship |
The support through a scholarship to DPT by the German Academic Exchange Service (DAAD) is greatly acknowledged. This research was funded by
Google.org, the philanthropic arm of Google. We are grateful to Francis Mulwa and James Wauna for assistance in field
experiments and other individuals at the communities who helped in the
same capacity. We acknowledge the technical assistance of Dunston Betti,
John Gachoya and Joel Lutomiah, Kenya Medical Research Institute
(KEMRI) and James Mutysia of Walter Reed Project (WRP), Nairobi. Our
sincere gratitude to Dr. Salifu Daisy, Mrs Caroline Tigoi, and Mr. Benedict
Orindi, International Centre of Insect Physiology and Ecology (icipe),
Nairobi. We appreciate the services of the chiefs at the trapping
communities both at Marigat and Ijara districts. The Arbovirus Incidence
and Diversity Project consortium-icipe, International Livestock Research
Institute (ILRI), Kenya Agricultural Research Institute (KARI), Kenya
Ministry of Livestock-Department of Veterinary Services (DVS), KEMRI,
Kenya Ministry of Public Health and Sanitation and Kenya Wildlife
Service (KWS). |
en |
dc.description.uri |
www.plosntds.org |
en |
dc.identifier.citation |
Tchouassi DP, Sang R, Sole CL, Bastos ADS, Teal PEA, et al. (2013) Common Host-Derived Chemicals Increase Catches of Disease-Transmitting Mosquitoes and Can Improve Early Warning Systems for Rift Valley Fever Virus. PLoS Negl Trop Dis 7(1): e2007. DOI: 10.1371/journal.pntd.0002007 |
en |
dc.identifier.issn |
1935-2727 |
|
dc.identifier.other |
10.1371/journal.pntd.0002007 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/21186 |
|
dc.language.iso |
en |
en |
dc.publisher |
Public Library of Science |
en |
dc.rights |
This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for
any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. |
en |
dc.subject |
Chemicals |
en |
dc.subject |
RVF (Disease) |
en |
dc.subject.lcsh |
Rift Valley fever |
en |
dc.subject.lcsh |
Mosquitoes |
en |
dc.subject.lcsh |
Zoonosis |
en |
dc.title |
Common host-derived chemicals increase catches of disease-transmitting mosquitoes and can improve early warning systems for rift valley fever virus |
en |
dc.type |
Article |
en |