Recently added

Medical Virology: Recent submissions

  • Changes in prevalence and seasonality of pathogens identified in acute respiratory tract infections in hospitalised individuals in rural and urban settings in South Africa; 2018–2022 
    Davids, Michaela; Johnstone, Siobhan; Mendes, Adriano; Brecht, Gadean; Avenant, Theunis Johannes; Du Plessis, Nicolette Marie; De Villiers, Maryke; Page, N.A. (Nicola); Venter, Marietjie (MDPI, 2024-03)
    Severe acute respiratory tract infections (SARIs) has been well described in South Africa with seasonal patterns described for influenza and respiratory syncytial virus (RSV), while others occur year-round (rhinovirus and ...
  • West Nile virus, an underdiagnosed cause of acute fever of unknown origin and neurological disease among hospitalized patients in South Africa 
    MacIntyre, Caitlin; Lourens, Carla; Mendes, Adriano; De Villiers, Maryke; Avenant, Theunis Johannes; Du Plessis, Nicolette Marie; Leendertz, Fabian; Venter, Marietjie (MDPI, 2023-11-02)
    West Nile virus (WNV), a mosquito-borne flavivirus, is endemic to South Africa. However, its contribution to acute febrile and neurological disease in hospitalized patients in South Africa is unknown. This study examined ...
  • Robust evidence for bats as reservoir hosts is lacking in most African virus studies : a review and call to optimize sampling and conserve bats 
    Weber, Natalie; Nagy, Martina; Markotter, Wanda; Schaer, Juliane; Puechmaille, Sebastien J.; Sutton, Jack; Davalos, Liliana M.; Dusabe, Marie-Claire; Ejotre, Imran; Fenton, M. Brock; Knornschild, Mirjam; Lopez-Baucells, Adria; Medellin, Rodrigo A.; Mubareka, Samira; Nsengimana, Olivier; O’Mara, M. Teague; Racey, Paul A.; Tuttle, Merlin; Twizeyimana, Innocent; Vicente-Santos, Amanda; Tschapka, Marco; Voigt, Christian C.; Wikelski, Martin; Dechmann, Dina K.N.; Reeder, DeeAnn M. (Royal Society, 2023-11)
    Africa experiences frequent emerging disease outbreaks among humans, with bats often proposed as zoonotic pathogen hosts. We comprehensively reviewed virus–bat findings from papers published between 1978 and 2020 to ...
  • Viral maintenance and excretion dynamics of coronaviruses within an Egyptian rousette fruit bat maternal colony : considerations for spillover 
    Geldenhuys, Marike; Ross, Noam; Dietrich, Muriel; De Vries, J. Low; Mortlock, Marinda; Epstein, Jonathan H.; Weyer, Jacqueline; Paweska, Janusz Tadeusz; Markotter, Wanda (Nature Reseach, 2023-09)
    Novel coronavirus species of public health and veterinary importance have emerged in the first two decades of the twenty-first century, with bats identified as natural hosts for progenitors of many coronaviruses. Targeted ...
  • Stem cell transplant in immune-deficiency-associated vaccine-derived poliovirus 
    Ranchod, Heena; Howard, Wayne; Roux, Adele; Van Zyl, Walda B.; Ekermans, Pieter; Van den Berg, Sylvia; Seakamela, Lerato; Makua, Koketso; Yousif, Mukhlid; Sibiya, Rosinah; Du Plessis, Heleen; Phalane, Emmanuel; McCarthy, Kerrigan; Moonsamy, Shelina; Reynders, David; Hincks, Jeffrey; Suchard, Melinda S.; Du Plessis, Nicolette Marie (Oxford University Press, 2024-01)
    Patients with severe primary immunodeficiency are at risk for complications from live-attenuated vaccines. Here, we report a case of a vaccine-associated paralytic polio and Bacille Calmette-Guérin disease in a 6-month-old ...
  • Vector-borne protozoan and bacterial pathogen occurrence and diversity in ectoparasites of the Egyptian Rousette bat 
    Szentivanyi, Tamara; Heintz, Anne-Caroline; Markotter, Wanda; Wassef, Jerome; Christe, Philippe; Glaizot, Olivier (Wiley, 2023-06)
    Bats are known reservoir hosts for a wide variety of parasites and pathogens, including bacteria and protozoans. Some of these pathogens are vector-borne, and although their role is poorly studied, ectoparasites may ...
  • Race in health research : considerations for researchers and research ethics committees 
    Van Staden, Werdie; Nienaber, A.; Rossouw, T.; Turner, A.C. (Astrid); Filmalter, Cecilia Jacoba; Nel, Jan Gert; Bapela, S.; Beetge, Mia-Michaela; Blumenthal, Ryan; Castelyn, Camille De Villebois; De Witt-Jordaan, T.W. (Wilma); Dlagnekova, Antonia; Kotze, Carla; Mangwane, S.; Napoles, Lizeka; Somers, R.; Sykes, Leanne M.; Van Zyl, W.B.; Venter, Marietjie; Uys, Andre; Warren, Nichola (South African Medical Association, 2023-04)
    This article provides ethical guidance on using race in health research as a variable or in defining the study population. To this end, a plain, non-exhaustive checklist is provided for researchers and research ethics ...
  • The One Health high-level expert panel (OHHLEP) 
    Mettenleiter, Thomas C.; Markotter, Wanda; Charron, Dominique F.; Adisasmito, Wiku B.; Almuhairi, Salama; Behravesh, Casey Barton; Bilivogui, Pepe; Bukachi, Salome A.; Casas, Natalia; Becerra, Natalia Cediel; Chaudhary, Abhishek; Ciacci Zanella, Janice R.; Cunningham, Andrew A.; Dar, Osman; Debnath, Nitish; Dungu, Baptiste; Farag, Elmoubasher; Gao, George F.; Hayman, David T.S.; Khaitsa, Margaret; Koopmans, Marion P.G.; Machalaba, Catherine; Mackenzie, John S.; Morand, Serge; Smolenskiy, Vyacheslav; Zhou, Lei (BMC, 2023-12)
    No abstract available.
  • Developing One Health surveillance systems 
    Hayman, David T.S.; Adisasmito, Wiku B.; Almuhairi, Salama; Behravesh, Casey Barton; Bilivogui, Pépé; Bukachi, Salome A.; Casas, Natalia; Becerra, Natalia Cediel; Charron, Dominique F.; Chaudhary, Abhishek; Ciacci Zanella, Janice R.; Cunningham, Andrew A.; Dar, Osman; Debnath, Nitish; Dungu, Baptiste; Farag, Elmoubasher; Gao, George F.; Khaitsa, Margaret; Machalaba, Catherine; Mackenzie, John S.; Markotter, Wanda; Mettenleiter, Thomas C.; Morand, Serge; Smolenskiy, Vyacheslav; Zhou, Lei; Koopmans, Marion (Elsevier, 2023-12)
    The health of humans, domestic and wild animals, plants, and the environment are inter-dependent. Global anthropogenic change is a key driver of disease emergence and spread and leads to biodiversity loss and ecosystem ...
  • Microorganisms detected in intussusception cases and controls in children <3 years in South Africa from 2013 to 2017 
    Page, N.A. (Nicola); Netshikweta, Rembuluwani; Tate, Jacqueline E.; Madhi, Shabir A.; Parashar, Umesh D.; Groome, Michelle J. (Oxford University Press, 2023-09)
    A matched case-control evaluated infectious etiologies in children <3 years in post-rotavirus vaccine intussusception surveillance. Adenovirus and adenovirus types C, A, and B were detected more frequently in cases versus ...
  • Why the world needs more transparency on the origins of novel pathogens 
    Venter, Marietjie (Nature Research, 2023-06)
    Collaboration and openness are essential to minimize the risks of future pandemics, says the World Health Organization’s scientific advisory group, SAGO.
  • Multicountry study of SARS-CoV-2 and associated risk factors among healthcare workers in Cote d’Ivoire, Burkina Faso and South Africa 
    Kribi, Sarah; Toure, Fidele; Mendes, Adriano; Sanou, Soufiane; Some, Arsene; Aminou, Abdoul M.; Belarbi, Essia; Griessel, Rosemary; Hema, Arsene; Kabore, Firmin; Pitzinger, Paul; Strydom, Amy; Vietor, Ann Christin; Traore, Korotimi; Zongo, Arsene; Anoh, Etile A.; Grossegesse, Marica; Hofmann, Natalie; Ouangraoua, Soumeya; Poda, Armel; Kagone, Therese; Schubert, Grit; Eckmanns, Tim; Venter, Marietjie; Leendertz, Fabian; Akoua-Koffi, Chantal; Tomczyk, Sara (Oxford University Press, 2023-03)
    BACKGROUND : Reports on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread across Africa have varied, including among healthcare workers (HCWs). This study assessed the comparative SARS-CoV-2 burden and ...
  • Comparative neutralization activity of commercial rabies immunoglobulin against diverse lyssaviruses 
    Coertse, Jessica; Viljoen, Natalie; Weyer, Jacqueline; Markotter, Wanda (MDPI, 2023-07-18)
    Novel lyssaviruses, the causative agents of rabies, continue to be described mostly due to increased surveillance in bat hosts. Biologicals for the prevention of rabies in humans have, however, remained largely unchanged ...
  • Cytology compared with Hybrid Capture 2 human papilloma virus cervical cancer screening in HIV positive and HIV negative South African women 
    Snyman, Leon Cornelius; Richter, Karin Louise; widowi; Dreyer, Gerrit; Botha, Matthys Hendrik; Van der Merwe, F. Haynes; Visser, Cathy; Dreyer, Greta (BMJ Publishing, 2023-05)
    OBJECTIVES : Cervical cancer is preventable and caused by persistent infection with oncogenic human papilloma virus (HPV) types. HPV screening is more sensitive and is the preferred screening test. HPV screening data are ...
  • One Health action for health security and equity 
    Machalaba, Catherine; Adisasmito, Wiku B.; Almuhairi, Salama; Behravesh, Casey Barton; Bilivogui, Pepe; Bukachi, Salome A.; Becerra, Natalia Cediel; Charron, Dominique F.; Chaudhary, Abhishek; Zanella, Janice R. Ciacci; Cunningham, Andrew A.; Dar, Osman; Debnath, Nitish; Dungu, Baptiste; Farag, Elmoubasher; Gao, George F.; Hayman, David T.S.; Khaitsa, Margaret; Koopmans, Marion P.G.; Mackenzie, John S.; Markotter, Wanda; Mettenleiter, Thomas C.; Morand, Serge; Smolenskiy, Vyacheslav; Zhou, Lei (Elsevier, 2023-02)
    The importance of integrated One Health approaches to reduce the likelihood and impacts of emerging infectious disease outbreaks has been widely accepted, as the Lancet series on One Health emphasises.1–4 However, ...
  • Transmission dynamics of Crimean–Congo haemorrhagic fever virus (CCHFV) : evidence of circulation in humans, livestock, and rodents in diverse ecologies in Kenya 
    Omoga, Dorcus Caroline Achieng; Tchouassi, David P.; Venter, Marietjie; Ogola, Edwin O.; Osalla, Josephine; Kopp, Anne; Slothouwer, Inga; Torto, Baldwyn; Junglen, Sandra; Sang, Rosemary (MDPI, 2023-09-03)
    Crimean–Congo haemorrhagic fever virus (CCHFV) is the causative agent of CCHF, a fatal viral haemorrhagic fever disease in humans. The maintenance of CCHFV in the ecosystem remains poorly understood. Certain tick species ...
  • Evaluation of taxonomic characteristics of Matlo and Phala bat rabies-related lyssaviruses identified in South Africa 
    Viljoen, Natalie; Weyer, Jacqueline; Coertse, Jessica; Markotter, Wanda (MDPI, 2023-10-04)
    We report the genetic characterization of two potentially novel rabies-related lyssaviruses identified from bats in Limpopo province, South Africa. Matlo bat lyssavirus (MBLV) was identified in two Miniopterus natalensis ...
  • Association between immunogenicity of a monovalent parenteral P2-VP8 subunit rotavirus vaccine and fecal shedding of rotavirus following Rotarix challenge during a randomized, double-blind, placebo-controlled trial 
    Fellows, Tamika; Page, Nicola Anne; Fix, Alan; Flores, Jorge; Cryz, Stanley; McNeal, Monica; Iturriza-Gomara, Miren; Groome, Michelle J. (MDPI, 2023-08-25)
    A correlate of protection for rotavirus (RV) has not been consistently identified. Shedding of RV following an oral rotavirus vaccine (ORV) challenge has been investigated as a potential model to assess protection of ...
  • Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa 
    Viana, Raquel; Moyo, Sikhulile; Amoako, Daniel G.; Tegally, Houriiyah; Scheepers, Cathrine; Althaus, Christian L.; Anyaneji, Ugochukwu J.; Bester, Phillip A.; Boni, Maciej F.; Chand, Mohammed; Choga, Wonderful T.; Colquhoun, Rachel; Davids, Michaela; Deforche, Koen; Doolabh, Deelan; Du Plessis, Louis; Engelbrecht, Susan; Everatt, Josie; Giandhari, Jennifer; Giovanetti, Marta; Hardie, Diana; Hill, Verity; Hsiao, Nei-Yuan; Iranzadeh, Arash; Ismail, Arshad; Joseph, Charity; Joseph, Rageema; Koopile, Legodile; Pond, Sergei L. Kosakovsky; Kraemer, Moritz U.G.; Kuate-Lere, Lesego; Laguda-Akingba, Oluwakemi; Lesetedi-Mafoko, Onalethatha; Lessells, Richard; Lockman, Shahin; Lucaci, Alexander G.; Maharaj, Arisha; Mahlangu, Boitshoko; Maponga, Tongai; Mahlakwane, Kamela; Makatini, Zinhle; Marais, Gert; Maruapula, Dorcas; Masupu, Kereng; Matshaba, Mogomotsi; Mayaphi, Simnikiwe; Mbhele, Nokuzola; Mbulawa, Mpaphi B.; Mendes, Adriano; Mlisana, Koleka; Mnguni, Anele; Mohale, Thabo; Moir, Monika; Moruisi, Kgomotso; Mosepele, Mosepele; Motsatsi, Gerald; Motswaledi, Modisa S.; Mphoyakgosi, Thongbotho; Msomi, Nokukhanya; Mwangi, Peter N.; Naidoo, Yeshnee; Ntuli, Noxolo; Nyaga, Martin; Olubayo, Lucier; Pillay, Sureshnee; Radibe, Botshelo; Ramphal, Yajna; Ramphal, Upasana; San, James E.; Scott, Lesley; Shapiro, Roger; Smith-Lawrence, Pamela; Stevens, Wendy; Strydom, Amy; Subramoney, Kathleen; Tebeila, Naume; Tshiabuila, Derek; Tsui, Joseph; Van Wyk, Stephanie; Weaver, Steven; Wibmer, Constantinos K.; Wilkinson, Eduan; Wolter, Nicole; Zarebski, Alexander E.; Zuze, Boitumelo; Goedhals, Dominique; Preise, Wolfgang; Treurnicht, Florette; Venter, Marietjie; Williamson, Carolyn; Pybus, Oliver G.; Bhiman, Jinal; Glass, Allison; Martin, Darren P.; Rambaut, Andrew; Gaseitsiwe, Simani; Von Gottberg, Anne; De Oliveira, Tulio (Nature Research, 2022-03-24)
    The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, while the second and third waves were driven by the Beta (B.1.351) ...
  • Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa 
    Tegally, Houriiyah; Moir, Monika; Everatt, Josie; Giovanetti, Marta; Scheepers, Cathrine; Wilkinson, Eduan; Subramoney, Kathleen; Makatini, Zinhle; Moyo, Sikhulile; Amoako, Daniel G.; Baxter, Cheryl; Althaus, Christian L.; Anyaneji, Ugochukwu J.; Kekana, Dikeledi; Viana, Raquel; Giandhari, Jennifer; Lessells, Richard; Maponga, Tongai; Maruapula, Dorcas; Choga, Wonderful; Matshaba, Mogomotsi; Mbulawa, Mpaphi B.; Msomi, Nokukhanya; NGS-SA consortium; Naidoo, Yeshnee; Pillay, Sureshnee; Sanko, Tomasz Janusz; San, James E.; Scott, Lesley; Singh, Lavanya; Magini, Nonkululeko A.; Smith-Lawrence, Pamela; Stevens, Wendy; Dor, Graeme; Tshiabuila, Derek; Wolter, Nicole; Preiser, Wolfgang; Treurnicht, Florette K.; Venter, Marietjie; Chiloane, Georginah; McIntyre, Caitlyn; O’Toole, Aine; Ruis, Christopher; Peacock, Thomas P.; Roemer, Cornelius; Pond, Sergei L. Kosakovsky; Williamson, Carolyn; Pybus, Oliver G.; Bhiman, Jinal N.; Glass, Allison; Martin, Darren P.; Jackson, Ben; Rambaut, Andrew; Laguda-Akingba, Oluwakemi; Gaseitsiwe, Simani; Von Gottberg, Anne; De Oliveira, Tulio; Bester, Armand Phillip; Claassen, Mathilda; Doolabh, Deelan; Mudau, Innocent; Mbhele, Nokuzola; Engelbrecht, Susan; Goedhals, Dominique; Hardie, Diana; Hsiao, Nei-Yuan; Iranzadeh, Arash; Ismail, Arshad; Joseph, Rageema; Maharaj, Arisha; Mahlangu, Boitshoko; Mahlakwane, Kamela; Davis, Ashlyn; Marais, Gert; Mlisana, Koleka; Mnguni, Anele; Mohale, Thabo; Motsatsi, Gerald; Mwangi, Peter; Ntuli, Noxolo; Nyaga, Martin; Olubayo, Luicer; Radibe, Botshelo; Ramphal, Yajna; Ramphal, Upasana; Strasheim, Wilhelmina; Tebeila, Naume; Van Wyk, Stephanie; Wilson, Shannon; Lucaci, Alexander G.; Weaver, Steven; Maharaj, Akhil; Pillay, Yusasha; Davids, Michaela; Mendes, Adriano; Mayaphi, Simnikiwe (Nature Research, 2022-09)
    Three lineages (BA.1, BA.2 and BA.3) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa’s fourth Coronavirus Disease 2019 (COVID-19) wave. We ...