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Browsing Research Articles (Haematology) by Issue Date
Now showing items 1-20 of 31
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(Society of Medical Laboratory Technologists of South Africa, 2010-06)INTRODUCTION: Pre-analytical variability currently represents the most important source of errors that can lead to inaccurate patient results in monitoring of patients being treated with oral anticoagulant therapy. The ...
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(Health and Medical Publishing Group, 2011-09)A 5-month-old South African girl presented to a casualty department with a short history of fever. General examination did not reveal organomegaly or neck stiffness. In keeping with local guidelines, malaria was excluded ...
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(Public Library of Science, 2013-12-20)BACKGROUND: Point of Care testing (POCT) provides on-site, rapid, accessible results. With current South African anti-retroviral treatment guidelines, up to 4 fingersticks /patient/clinic visit could be required if utilizing ...
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(Wiley, 2015-02)Haemophilia A severity is closely correlated to the factor VIII (FVIII) activity, which can be measured in different ways. The original one-stage clotting assay is still the most widely used. The two-stage coagulation ...
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(In House Publications, 2016)Haematological abnormalities are frequently encountered in the obstetric patient. Cytopenias are common, with anaemia and thrombocytopenia predominating. Many other haematological conditions are seen during pregnancy, ...
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(Lippincott Williams and Wilkins, 2016-02)BACKGROUND : A plethora of point-of-care (POC) tests exist in the HIV and tuberculosis diagnostic pipeline which require rigorous evaluation to ensure performance in the field. The accuracy and feasibility of nurse-operated ...
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(Public Library of Science, 2016-08-24)INTRODUCTION HIV-infected patients require antiretroviral treatment for life. To improve access to care, CD4 enumeration and viral load tests have been redesigned to be used as point-of-care techniques using finger-stick ...
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(Elsevier, 2016-09)Chronic infection with hepatitis B virus (HBV) remains an important global health problem. Currently licensed therapies have modest curative efficacy, which is as a result of their transient effects and limited action ...
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(Spandidos Publications, 2017)Micro‑ribonucleic acids (miRNAs) are small functional non‑coding RNAs that downregulate gene expression at the post‑transcriptional level. Abnormal expression of specific miRNAs has been recorded in chronic lymphocytic ...
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Acute megakaryoblastic leukaemia: light microscopy and scanning electron microscopy of blast cells (Wiley, 2017-03)A 60-year-old human immunodeficiency virus-positive woman presented with splenomegaly.
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(Society of Medical Laboratory Technologists of South Africa, 2017-06)This study aimed to examine the number and type of cancer diagnoses made based on bone marrow aspirates (BMA) using morphology and/or histology, over a three year period. All the data collected (2012-2015) was obtained ...
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(Society of Medical Laboratory Technologists of South Africa, 2017-06)Flow cytometry is a globally accepted diagnostic tool used for the rapid identification of cells based on their surface and intracellular antigens, especially for the diagnosis of haematological malignancies. The aim of ...
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(Health and Medical Publishing Group, 2017-09)BACKGROUND. The number of peripheral blood and endometrial natural killer cells varies greatly during implantation and the first trimester of pregnancy and is thought to play a role in the maintenance of a healthy pregnancy. ...
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(BioMed Central, 2017-10-10)Amongst males, leukaemia is the most common cause of cancer-related death in individuals younger than 40 years of age whereas in female children and adolescents, leukaemia is the most common cause of cancer-related ...
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(Hindawi Publishing Corporation, 2017-11-07)Acute myeloid leukemia (AML) is characterized by proliferation of the myeloid lineage and accumulation of immature hematopoietic cells in the bone marrow and is typified by marked heterogeneity both in response to treatment ...
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(AOSIS Open Journals, 2018-01-31)The purpose of this study was to develop a real time polymerase chain reaction (PCR) assay for the detection of the JAK2 V617F mutation that could be used in diagnostic laboratories. Sanger sequencing and a newly developed ...
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(MDPI Publishing, 2018-04-11)Pneumolysin (PLY), a member of the family of Gram-positive bacterial, cholesterol-dependent, -barrel pore-forming cytolysins, is the major protein virulence factor of the dangerous respiratory pathogen, Streptococcus ...
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(Wiley, 2018-08)INTRODUCTION : To determine whether the current set of evaluation criteria used for dilute Russel Viper Venom Time (dRVVT) investigations in the routine laboratory meet expectation and identify possible shortcomings. METHODS ...
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(Frontiers Media, 2018-11-20)Although the inclusion of the cationic amphiphilic, anti-mycobacterial agent, clofazimine, in the chemotherapeutic regimens of patients with multidrug-resistant tuberculosis (TB) has contributed to improved outcomes, ...
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(Health and Medical Publishing Group, 2019-09)Human immunodeficiency virus (HIV) infection not only leads to a compromised immune system, but also disrupts normal haematopoiesis, resulting in the frequent manifestation of cytopenias (anaemia, thrombocytopenia and ...
Now showing items 1-20 of 31