1907 Report of the Government Veterinary Bacteriologist of the Transvaal 1907 - 1908http://hdl.handle.net/2263/95942024-03-29T14:21:57Z2024-03-29T14:21:57ZOn the variability of a particular strain of horsesickness virusTheiler, Arnold, Sir, 1867-1936http://hdl.handle.net/2263/121672022-04-08T22:50:35Z1909-01-01T00:00:00ZOn the variability of a particular strain of horsesickness virus
Theiler, Arnold, Sir, 1867-1936
Transvaal Department of Agriculture
Conclusions:
1. The virus Tzaneen has in no instance been virulent for all mules injected; this virulency differs, so to say, from animal to animal; one particular animal seems to influence the virus in such a way that this virulency is either decreased or increased.
2. This reduction of virulency is by no means the result of the dose of virus or of method of injection; small and large doses, injected subcutaneously or intra-jugularly, equally fail to produce reactions.
3. This difference in virulency is either due to the virus itself or to the injected animal, but considering that animals which resisted quantities of virus of one particular type, subcutaneously or intra-jugularly, contract horse-sickness from a subsequent subcutaneous injection of a smaller quantity, it shows that it is not so much the resistance of the animal but the virulency of the virus of the given animal.
4. It is probably correct to conclude that both animal and virus must be in a certain relation to each other before a reaction can ensue.
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1909-01-01T00:00:00ZThe loss of virulency of horsesickness virus in practiceTheiler, Arnold, Sir, 1867-1936http://hdl.handle.net/2263/121662022-04-08T22:50:33Z1909-01-01T00:00:00ZThe loss of virulency of horsesickness virus in practice
Theiler, Arnold, Sir, 1867-1936
Transvaal Department of Agriculture
Resume:
The experiments prove that a virus may become inert in practice; this avirulency is due to some foreign matter, inasmuch as inert virus added to virulent sterile virus promptly produces avirulency. It is probable that this avirulency is due to the presence of some germ, but the experiments have not been carried out to the extent necessary to determine the nature of this micro-organism.
Conclusions:
1. The avirulency of a virus takes place a certain time after mixing sterile to inert virus.
2. The avirulency takes place more rapidly when the mixture is kept in the incubator than when it is kept at room temperature.
3. The mixture of virulent and inert virus produces different results in injected animals according' 1"0 the method of inoculation. The same virus which proves inert after a subcutaneous injection may be virulent for an intrajugular injection.
4. The intrajugular injection of large doses of inert virus does not produce immunity.
5. It is clear that a certain virus may become inert, and therefore this fact influences the preparation and preservation of virus to be used in practice.
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1909-01-01T00:00:00ZElectric conductivityFrei, Walterhttp://hdl.handle.net/2263/121652022-04-08T22:45:53Z1909-01-01T00:00:00ZElectric conductivity
Frei, Walter
Transvaal Department of Agriculture
Experiments were carried out to study quantitatively the influence of various organic colloids in different concentrations on the conductivity of the same electrolyte, that is to say, the influence of albumine, globuline, gelatine, and saponine on the ions Na and OH. Albumine and globuline are colloidal components of serum wherein also both ions are present.
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1909-01-01T00:00:00ZLetter of transmittalTheiler, Arnold, Sir, 1867-1936http://hdl.handle.net/2263/121642022-04-08T22:46:40Z1909-01-01T00:00:00ZLetter of transmittal
Theiler, Arnold, Sir, 1867-1936
Transvaal Department of Agriculture
1909-01-01T00:00:00Z